112 related articles for article (PubMed ID: 20373302)
1. The identification of a novel natural activator of p300 histone acetyltranferase provides new insights into the modulation mechanism of this enzyme.
Dal Piaz F; Tosco A; Eletto D; Piccinelli AL; Moltedo O; Franceschelli S; Sbardella G; Remondelli P; Rastrelli L; Vesci L; Pisano C; De Tommasi N
Chembiochem; 2010 Apr; 11(6):818-27. PubMed ID: 20373302
[TBL] [Abstract][Full Text] [Related]
2. Comparison of the cytotoxic effects of enantiopure PPAPs, including nemorosone and clusianone.
Simpkins NS; Holtrup F; Rodeschini V; Taylor JD; Wolf R
Bioorg Med Chem Lett; 2012 Oct; 22(19):6144-7. PubMed ID: 22944119
[TBL] [Abstract][Full Text] [Related]
3. Structure-activity relationship and antitumor activity of 1,4-pyrazine-containing inhibitors of histone acetyltransferases P300/CBP.
Nie S; Wu F; Wu J; Li X; Zhou C; Yao Y; Song Y
Eur J Med Chem; 2022 Jul; 237():114407. PubMed ID: 35512565
[TBL] [Abstract][Full Text] [Related]
4. The structural basis of protein acetylation by the p300/CBP transcriptional coactivator.
Liu X; Wang L; Zhao K; Thompson PR; Hwang Y; Marmorstein R; Cole PA
Nature; 2008 Feb; 451(7180):846-50. PubMed ID: 18273021
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer.
Ding H; Pei Y; Li Y; Xu W; Mei L; Hou Z; Guang Y; Cao L; Li P; Cao H; Bian J; Chen K; Luo C; Zhou B; Zhang T; Li Z; Yang Y
Bioorg Med Chem; 2021 Dec; 52():116512. PubMed ID: 34801827
[TBL] [Abstract][Full Text] [Related]
6. Curcumin-induced histone hypoacetylation: the role of reactive oxygen species.
Kang J; Chen J; Shi Y; Jia J; Zhang Y
Biochem Pharmacol; 2005 Apr; 69(8):1205-13. PubMed ID: 15794941
[TBL] [Abstract][Full Text] [Related]
7. Identification of structural features of 2-alkylidene-1,3-dicarbonyl derivatives that induce inhibition and/or activation of histone acetyltransferases KAT3B/p300 and KAT2B/PCAF.
Castellano S; Milite C; Feoli A; Viviano M; Mai A; Novellino E; Tosco A; Sbardella G
ChemMedChem; 2015 Jan; 10(1):144-57. PubMed ID: 25333655
[TBL] [Abstract][Full Text] [Related]
8. 5-Fluorouracil targets histone acetyltransferases p300/CBP in the treatment of colorectal cancer.
Du C; Huang D; Peng Y; Yao Y; Zhao Y; Yang Y; Wang H; Cao L; Zhu WG; Gu J
Cancer Lett; 2017 Aug; 400():183-193. PubMed ID: 28465257
[TBL] [Abstract][Full Text] [Related]
9. Novel curcumin analog C66 prevents diabetic nephropathy via JNK pathway with the involvement of p300/CBP-mediated histone acetylation.
Wang Y; Wang Y; Luo M; Wu H; Kong L; Xin Y; Cui W; Zhao Y; Wang J; Liang G; Miao L; Cai L
Biochim Biophys Acta; 2015 Jan; 1852(1):34-46. PubMed ID: 25446993
[TBL] [Abstract][Full Text] [Related]
10. Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.
Lasko LM; Jakob CG; Edalji RP; Qiu W; Montgomery D; Digiammarino EL; Hansen TM; Risi RM; Frey R; Manaves V; Shaw B; Algire M; Hessler P; Lam LT; Uziel T; Faivre E; Ferguson D; Buchanan FG; Martin RL; Torrent M; Chiang GG; Karukurichi K; Langston JW; Weinert BT; Choudhary C; de Vries P; Van Drie JH; McElligott D; Kesicki E; Marmorstein R; Sun C; Cole PA; Rosenberg SH; Michaelides MR; Lai A; Bromberg KD
Nature; 2017 Oct; 550(7674):128-132. PubMed ID: 28953875
[TBL] [Abstract][Full Text] [Related]
11. Modulation of p300/CBP Acetylation of Nucleosomes by Bromodomain Ligand I-CBP112.
Zucconi BE; Luef B; Xu W; Henry RA; Nodelman IM; Bowman GD; Andrews AJ; Cole PA
Biochemistry; 2016 Jul; 55(27):3727-34. PubMed ID: 27332697
[TBL] [Abstract][Full Text] [Related]
12. Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors.
Lu W; Xiong H; Chen Y; Wang C; Zhang H; Xu P; Han J; Xiao S; Ding H; Chen Z; Lu T; Wang J; Zhang Y; Yue L; Liu YC; Zhang C; Yang Y; Jiang H; Chen K; Zhou B; Luo C
Bioorg Med Chem; 2018 Nov; 26(20):5397-5407. PubMed ID: 30297119
[TBL] [Abstract][Full Text] [Related]
13. Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome.
Weinert BT; Narita T; Satpathy S; Srinivasan B; Hansen BK; Schölz C; Hamilton WB; Zucconi BE; Wang WW; Liu WR; Brickman JM; Kesicki EA; Lai A; Bromberg KD; Cole PA; Choudhary C
Cell; 2018 Jun; 174(1):231-244.e12. PubMed ID: 29804834
[TBL] [Abstract][Full Text] [Related]
14. Small-molecule inhibitors of acetyltransferase p300 identified by high-throughput screening are potent anticancer agents.
Yang H; Pinello CE; Luo J; Li D; Wang Y; Zhao LY; Jahn SC; Saldanha SA; Chase P; Planck J; Geary KR; Ma H; Law BK; Roush WR; Hodder P; Liao D
Mol Cancer Ther; 2013 May; 12(5):610-20. PubMed ID: 23625935
[TBL] [Abstract][Full Text] [Related]
15. Discovery, Structure-Activity Relationship, and Biological Activity of Histone-Competitive Inhibitors of Histone Acetyltransferases P300/CBP.
Wu F; Hua Y; Kaochar S; Nie S; Lin YL; Yao Y; Wu J; Wu X; Fu X; Schiff R; Davis CM; Robertson M; Ehli EA; Coarfa C; Mitsiades N; Song Y
J Med Chem; 2020 May; 63(9):4716-4731. PubMed ID: 32314924
[TBL] [Abstract][Full Text] [Related]
16. Critical loss of CBP/p300 histone acetylase activity by caspase-6 during neurodegeneration.
Rouaux C; Jokic N; Mbebi C; Boutillier S; Loeffler JP; Boutillier AL
EMBO J; 2003 Dec; 22(24):6537-49. PubMed ID: 14657026
[TBL] [Abstract][Full Text] [Related]
17. E2A proteins enhance the histone acetyltransferase activity of the transcriptional co-activators CBP and p300.
Hyndman BD; Thompson P; Bayly R; Côté GP; LeBrun DP
Biochim Biophys Acta; 2012 May; 1819(5):446-53. PubMed ID: 22387215
[TBL] [Abstract][Full Text] [Related]
18. Autoacetylation induced specific structural changes in histone acetyltransferase domain of p300: probed by surface enhanced Raman spectroscopy.
Arif M; Kumar GV; Narayana C; Kundu TK
J Phys Chem B; 2007 Oct; 111(41):11877-9. PubMed ID: 17894486
[TBL] [Abstract][Full Text] [Related]
19. Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones.
Deng L; de la Fuente C; Fu P; Wang L; Donnelly R; Wade JD; Lambert P; Li H; Lee CG; Kashanchi F
Virology; 2000 Nov; 277(2):278-95. PubMed ID: 11080476
[TBL] [Abstract][Full Text] [Related]
20. Histone deacetylase inhibitors synergize p300 autoacetylation that regulates its transactivation activity and complex formation.
Stiehl DP; Fath DM; Liang D; Jiang Y; Sang N
Cancer Res; 2007 Mar; 67(5):2256-2264. PubMed ID: 17332356
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]