These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

106 related articles for article (PubMed ID: 20375179)

  • 1. Use of the Øie-Tozer model in understanding mechanisms and determinants of drug distribution.
    Waters NJ; Lombardo F
    Drug Metab Dispos; 2010 Jul; 38(7):1159-65. PubMed ID: 20375179
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Øie-Tozer model of drug distribution and its suitability for drugs with different pharmacokinetic behavior.
    Stepensky D
    Expert Opin Drug Metab Toxicol; 2011 Oct; 7(10):1233-43. PubMed ID: 21919805
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Applicability of the Øie-Tozer model to predict three types of distribution volume (Vd) in humans: Vd in central compartment, Vd at steady state, and Vd at beta phase.
    Yahata M; Ishii Y; Nakagawa T; Watanabe T; Miyawaki I
    Biopharm Drug Dispos; 2020 Apr; 41(4-5):151-165. PubMed ID: 32187715
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Lombardo F; Obach RS; Shalaeva MY; Gao F
    J Med Chem; 2002 Jun; 45(13):2867-76. PubMed ID: 12061889
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    Sui X; Sun J; Li H; Wang Y; Liu J; Liu X; Zhang W; Chen L; He Z
    Eur J Med Chem; 2009 Nov; 44(11):4455-60. PubMed ID: 19586686
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prediction of volume of distribution at steady state in humans: comparison of different approaches.
    Zou P; Zheng N; Yang Y; Yu LX; Sun D
    Expert Opin Drug Metab Toxicol; 2012 Jul; 8(7):855-72. PubMed ID: 22591253
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Lombardo F; Obach RS; Shalaeva MY; Gao F
    J Med Chem; 2004 Feb; 47(5):1242-50. PubMed ID: 14971904
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Relative Performance of Volume of Distribution Prediction Methods for Lipophilic Drugs with Uncertainty in LogP Value.
    Coutinho AL; Cristofoletti R; Wu F; Al Shoyaib A; Dressman J; Polli JE
    Pharm Res; 2024 Jun; 41(6):1121-1138. PubMed ID: 38720034
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of a novel method for predicting human volume of distribution at steady-state of basic drugs and comparative assessment with existing methods.
    Poulin P; Theil FP
    J Pharm Sci; 2009 Dec; 98(12):4941-61. PubMed ID: 19455625
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An Accurate In Vitro Prediction of Human VD
    Berellini G; Lombardo F
    Drug Metab Dispos; 2019 Dec; 47(12):1380-1387. PubMed ID: 31578209
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Species differences in distribution and prediction of human V(ss) from preclinical data.
    Berry LM; Li C; Zhao Z
    Drug Metab Dispos; 2011 Nov; 39(11):2103-16. PubMed ID: 21852367
    [TBL] [Abstract][Full Text] [Related]  

  • 12. On the accuracy of estimation of basic pharmacokinetic parameters by the traditional noncompartmental equations and the prediction of the steady-state volume of distribution in obese patients based upon data derived from normal subjects.
    Berezhkovskiy LM
    J Pharm Sci; 2011 Jun; 100(6):2482-97. PubMed ID: 21254063
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ADME evaluation in drug discovery. 3. Modeling blood-brain barrier partitioning using simple molecular descriptors.
    Hou TJ; Xu XJ
    J Chem Inf Comput Sci; 2003; 43(6):2137-52. PubMed ID: 14632466
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 2: comparative assessment of prediction methods of human volume of distribution.
    Jones RD; Jones HM; Rowland M; Gibson CR; Yates JW; Chien JY; Ring BJ; Adkison KK; Ku MS; He H; Vuppugalla R; Marathe P; Fischer V; Dutta S; Sinha VK; Björnsson T; Lavé T; Poulin P
    J Pharm Sci; 2011 Oct; 100(10):4074-89. PubMed ID: 21452299
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prediction of drug terminal half-life and terminal volume of distribution after intravenous dosing based on drug clearance, steady-state volume of distribution, and physiological parameters of the body.
    Berezhkovskiy LM
    J Pharm Sci; 2013 Feb; 102(2):761-71. PubMed ID: 23233148
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comprehensive assessment of human pharmacokinetic prediction based on in vivo animal pharmacokinetic data, part 1: volume of distribution at steady state.
    Lombardo F; Waters NJ; Argikar UA; Dennehy MK; Zhan J; Gunduz M; Harriman SP; Berellini G; Rajlic IL; Obach RS
    J Clin Pharmacol; 2013 Feb; 53(2):167-77. PubMed ID: 23436262
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 4: prediction of plasma concentration-time profiles in human from in vivo preclinical data by using the Wajima approach.
    Vuppugalla R; Marathe P; He H; Jones RD; Yates JW; Jones HM; Gibson CR; Chien JY; Ring BJ; Adkison KK; Ku MS; Fischer V; Dutta S; Sinha VK; Björnsson T; Lavé T; Poulin P
    J Pharm Sci; 2011 Oct; 100(10):4111-26. PubMed ID: 21480234
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development and application of physiologically based pharmacokinetic-modeling tools to support drug discovery.
    Lüpfert C; Reichel A
    Chem Biodivers; 2005 Nov; 2(11):1462-86. PubMed ID: 17191947
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prediction of volume of distribution in humans: analysis of eight methods and their application in drug discovery.
    Petersson C; Papasouliotis O; Lecomte M; Badolo L; Dolgos H
    Xenobiotica; 2020 Mar; 50(3):270-279. PubMed ID: 31215316
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The impact of the concentration of drug binding plasma proteins on drug distribution according to Øie-Tozer's model.
    Svennebring AM
    Xenobiotica; 2016; 46(4):307-14. PubMed ID: 26259025
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.