253 related articles for article (PubMed ID: 20375271)
1. Lovastatin induces VSMC differentiation through inhibition of Rheb and mTOR.
Wagner RJ; Martin KA; Powell RJ; Rzucidlo EM
Am J Physiol Cell Physiol; 2010 Jul; 299(1):C119-27. PubMed ID: 20375271
[TBL] [Abstract][Full Text] [Related]
2. Tumorigenic activity and therapeutic inhibition of Rheb GTPase.
Mavrakis KJ; Zhu H; Silva RL; Mills JR; Teruya-Feldstein J; Lowe SW; Tam W; Pelletier J; Wendel HG
Genes Dev; 2008 Aug; 22(16):2178-88. PubMed ID: 18708578
[TBL] [Abstract][Full Text] [Related]
3. Specific activation of mTORC1 by Rheb G-protein in vitro involves enhanced recruitment of its substrate protein.
Sato T; Nakashima A; Guo L; Tamanoi F
J Biol Chem; 2009 May; 284(19):12783-91. PubMed ID: 19299511
[TBL] [Abstract][Full Text] [Related]
4. Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1.
Zheng M; Wang YH; Wu XN; Wu SQ; Lu BJ; Dong MQ; Zhang H; Sun P; Lin SC; Guan KL; Han J
Nat Cell Biol; 2011 Mar; 13(3):263-72. PubMed ID: 21336308
[TBL] [Abstract][Full Text] [Related]
5. The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity.
Basso AD; Mirza A; Liu G; Long BJ; Bishop WR; Kirschmeier P
J Biol Chem; 2005 Sep; 280(35):31101-8. PubMed ID: 16006564
[TBL] [Abstract][Full Text] [Related]
6. MCRS1 binds and couples Rheb to amino acid-dependent mTORC1 activation.
Fawal MA; Brandt M; Djouder N
Dev Cell; 2015 Apr; 33(1):67-81. PubMed ID: 25816988
[TBL] [Abstract][Full Text] [Related]
7. Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling.
Wang X; Fonseca BD; Tang H; Liu R; Elia A; Clemens MJ; Bommer UA; Proud CG
J Biol Chem; 2008 Nov; 283(45):30482-92. PubMed ID: 18676370
[TBL] [Abstract][Full Text] [Related]
8. Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb.
Lee MN; Ha SH; Kim J; Koh A; Lee CS; Kim JH; Jeon H; Kim DH; Suh PG; Ryu SH
Mol Cell Biol; 2009 Jul; 29(14):3991-4001. PubMed ID: 19451232
[TBL] [Abstract][Full Text] [Related]
9. PDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding protein (CREB)-Ras homolog enriched in brain (RHEB)-mTORC1 signaling cascade.
Liu Z; Chen X; Wang Y; Peng H; Wang Y; Jing Y; Zhang H
J Biol Chem; 2014 Oct; 289(43):29739-49. PubMed ID: 25164809
[TBL] [Abstract][Full Text] [Related]
10. Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity.
Carroll B; Maetzel D; Maddocks OD; Otten G; Ratcliff M; Smith GR; Dunlop EA; Passos JF; Davies OR; Jaenisch R; Tee AR; Sarkar S; Korolchuk VI
Elife; 2016 Jan; 5():. PubMed ID: 26742086
[TBL] [Abstract][Full Text] [Related]
11. Mammalian target of rapamycin activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial carcinogenesis.
Lu ZH; Shvartsman MB; Lee AY; Shao JM; Murray MM; Kladney RD; Fan D; Krajewski S; Chiang GG; Mills GB; Arbeit JM
Cancer Res; 2010 Apr; 70(8):3287-98. PubMed ID: 20388784
[TBL] [Abstract][Full Text] [Related]
12. Mammalian target of rapamycin complex I (mTORC1) activity in ras homologue enriched in brain (Rheb)-deficient mouse embryonic fibroblasts.
Groenewoud MJ; Goorden SM; Kassies J; Pellis-van Berkel W; Lamb RF; Elgersma Y; Zwartkruis FJ
PLoS One; 2013; 8(11):e81649. PubMed ID: 24303063
[TBL] [Abstract][Full Text] [Related]
13. The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signalling and leads to chronic heart failure.
Xu N; Guan S; Chen Z; Yu Y; Xie J; Pan FY; Zhao NW; Liu L; Yang ZZ; Gao X; Xu B; Li CJ
J Pathol; 2015 Apr; 235(5):672-85. PubMed ID: 25385233
[TBL] [Abstract][Full Text] [Related]
14. cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity.
Xie J; Ponuwei GA; Moore CE; Willars GB; Tee AR; Herbert TP
Cell Signal; 2011 Dec; 23(12):1927-35. PubMed ID: 21763421
[TBL] [Abstract][Full Text] [Related]
15. Cyclic AMP controls mTOR through regulation of the dynamic interaction between Rheb and phosphodiesterase 4D.
Kim HW; Ha SH; Lee MN; Huston E; Kim DH; Jang SK; Suh PG; Houslay MD; Ryu SH
Mol Cell Biol; 2010 Nov; 30(22):5406-20. PubMed ID: 20837708
[TBL] [Abstract][Full Text] [Related]
16. Ursolic acid inhibits leucine-stimulated mTORC1 signaling by suppressing mTOR localization to lysosome.
Ou X; Liu M; Luo H; Dong LQ; Liu F
PLoS One; 2014; 9(4):e95393. PubMed ID: 24740400
[TBL] [Abstract][Full Text] [Related]
17. Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.
Karbowniczek M; Cash T; Cheung M; Robertson GP; Astrinidis A; Henske EP
J Biol Chem; 2004 Jul; 279(29):29930-7. PubMed ID: 15150271
[TBL] [Abstract][Full Text] [Related]
18. Rheb regulates nuclear mTORC1 activity independent of farnesylation.
Zhong Y; Zhou X; Guan KL; Zhang J
Cell Chem Biol; 2022 Jun; 29(6):1037-1045.e4. PubMed ID: 35294906
[TBL] [Abstract][Full Text] [Related]
19. Weak membrane interactions allow Rheb to activate mTORC1 signaling without major lysosome enrichment.
Angarola B; Ferguson SM
Mol Biol Cell; 2019 Oct; 30(22):2750-2760. PubMed ID: 31532697
[TBL] [Abstract][Full Text] [Related]
20. Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling.
Hanker AB; Mitin N; Wilder RS; Henske EP; Tamanoi F; Cox AD; Der CJ
Oncogene; 2010 Jan; 29(3):380-91. PubMed ID: 19838215
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
