These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 20378549)

  • 1. Molecular mechanism that induces activation of Spätzle, the ligand for the Drosophila Toll receptor.
    Arnot CJ; Gay NJ; Gangloff M
    J Biol Chem; 2010 Jun; 285(25):19502-9. PubMed ID: 20378549
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling.
    Weber AN; Tauszig-Delamasure S; Hoffmann JA; Lelièvre E; Gascan H; Ray KP; Morse MA; Imler JL; Gay NJ
    Nat Immunol; 2003 Aug; 4(8):794-800. PubMed ID: 12872120
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of the Spatzle Pro-domain in the generation of an active toll receptor ligand.
    Weber AN; Gangloff M; Moncrieffe MC; Hyvert Y; Imler JL; Gay NJ
    J Biol Chem; 2007 May; 282(18):13522-31. PubMed ID: 17324925
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity.
    Jang IH; Chosa N; Kim SH; Nam HJ; Lemaitre B; Ochiai M; Kambris Z; Brun S; Hashimoto C; Ashida M; Brey PT; Lee WJ
    Dev Cell; 2006 Jan; 10(1):45-55. PubMed ID: 16399077
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evolutionary and functional epitopes of the Spätzle protein: new insights into activation of the Toll receptor.
    Wang Y; Zhu S
    Cell Mol Life Sci; 2009 May; 66(9):1595-602. PubMed ID: 19308321
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ligand-receptor and receptor-receptor interactions act in concert to activate signaling in the Drosophila toll pathway.
    Weber AN; Moncrieffe MC; Gangloff M; Imler JL; Gay NJ
    J Biol Chem; 2005 Jun; 280(24):22793-9. PubMed ID: 15795223
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity.
    Parthier C; Stelter M; Ursel C; Fandrich U; Lilie H; Breithaupt C; Stubbs MT
    Proc Natl Acad Sci U S A; 2014 Apr; 111(17):6281-6. PubMed ID: 24733933
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A family of proteins related to Spätzle, the toll receptor ligand, are encoded in the Drosophila genome.
    Parker JS; Mizuguchi K; Gay NJ
    Proteins; 2001 Oct; 45(1):71-80. PubMed ID: 11536362
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Spätzle-Processing Enzyme-independent Activation of the Toll Pathway in Drosophila Innate Immunity.
    Yamamoto-Hino M; Goto S
    Cell Struct Funct; 2016 May; 41(1):55-60. PubMed ID: 26843333
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High level expression of the Drosophila Toll receptor ectodomain and crystallization of its complex with the morphogen Spätzle.
    Stelter M; Fandrich U; Franzke K; Schierhorn A; Breithaupt C; Parthier C; Stubbs MT
    Biol Chem; 2013 Aug; 394(8):1091-6. PubMed ID: 23729564
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Localization and activation of the Drosophila protease easter require the ER-resident saposin-like protein seele.
    Stein D; Charatsi I; Cho YS; Zhang Z; Nguyen J; DeLotto R; Luschnig S; Moussian B
    Curr Biol; 2010 Nov; 20(21):1953-8. PubMed ID: 20970335
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A three-step proteolytic cascade mediates the activation of the peptidoglycan-induced toll pathway in an insect.
    Kim CH; Kim SJ; Kan H; Kwon HM; Roh KB; Jiang R; Yang Y; Park JW; Lee HH; Ha NC; Kang HJ; Nonaka M; Söderhäll K; Lee BL
    J Biol Chem; 2008 Mar; 283(12):7599-607. PubMed ID: 18195005
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of translation and proteolysis during the development of embryonic dorso-ventral polarity in Drosophila. Homology of easter proteinase with Limulus proclotting enzyme and translational activation of Toll receptor synthesis.
    Gay NJ; Keith FJ
    Biochim Biophys Acta; 1992 Oct; 1132(3):290-6. PubMed ID: 1420309
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The spätzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo.
    Morisato D; Anderson KV
    Cell; 1994 Feb; 76(4):677-88. PubMed ID: 8124709
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural insight into the mechanism of activation of the Toll receptor by the dimeric ligand Spätzle.
    Gangloff M; Murali A; Xiong J; Arnot CJ; Weber AN; Sandercock AM; Robinson CV; Sarisky R; Holzenburg A; Kao C; Gay NJ
    J Biol Chem; 2008 May; 283(21):14629-35. PubMed ID: 18347020
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro maturation of Drosophila melanogaster Spätzle protein with refolded Easter reveals a novel cleavage site within the prodomain.
    Ursel C; Fandrich U; Hoffmann A; Sieg T; Ihling C; Stubbs MT
    Biol Chem; 2013 Aug; 394(8):1069-75. PubMed ID: 23729565
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cytokine Spatzle binds to the Drosophila immunoreceptor Toll with a neurotrophin-like specificity and couples receptor activation.
    Lewis M; Arnot CJ; Beeston H; McCoy A; Ashcroft AE; Gay NJ; Gangloff M
    Proc Natl Acad Sci U S A; 2013 Dec; 110(51):20461-6. PubMed ID: 24282309
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Proteolytic cascade for the activation of the insect toll pathway induced by the fungal cell wall component.
    Roh KB; Kim CH; Lee H; Kwon HM; Park JW; Ryu JH; Kurokawa K; Ha NC; Lee WJ; Lemaitre B; Söderhäll K; Lee BL
    J Biol Chem; 2009 Jul; 284(29):19474-81. PubMed ID: 19473968
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evolutionary relationships, but functional differences, between the Drosophila and human Toll-like receptor families.
    Gangloff M; Weber AN; Gibbard RJ; Gay NJ
    Biochem Soc Trans; 2003 Jun; 31(Pt 3):659-63. PubMed ID: 12773177
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Proteolytic activation and function of the cytokine Spätzle in the innate immune response of a lepidopteran insect, Manduca sexta.
    An C; Jiang H; Kanost MR
    FEBS J; 2010 Jan; 277(1):148-62. PubMed ID: 19968713
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.