94 related articles for article (PubMed ID: 20382159)
1. X-ray structures of the LXRalpha LBD in its homodimeric form and implications for heterodimer signaling.
Fradera X; Vu D; Nimz O; Skene R; Hosfield D; Wynands R; Cooke AJ; Haunsø A; King A; Bennett DJ; McGuire R; Uitdehaag JC
J Mol Biol; 2010 May; 399(1):120-32. PubMed ID: 20382159
[TBL] [Abstract][Full Text] [Related]
2. Design, structure activity relationships and X-Ray co-crystallography of non-steroidal LXR agonists.
Bennett DJ; Carswell EL; Cooke AJ; Edwards AS; Nimz O
Curr Med Chem; 2008; 15(2):195-209. PubMed ID: 18220775
[TBL] [Abstract][Full Text] [Related]
3. Crystal structure of the heterodimeric complex of LXRalpha and RXRbeta ligand-binding domains in a fully agonistic conformation.
Svensson S; Ostberg T; Jacobsson M; Norström C; Stefansson K; Hallén D; Johansson IC; Zachrisson K; Ogg D; Jendeberg L
EMBO J; 2003 Sep; 22(18):4625-33. PubMed ID: 12970175
[TBL] [Abstract][Full Text] [Related]
4. The medicinal chemistry of liver X receptor (LXR) modulators.
Tice CM; Noto PB; Fan KY; Zhuang L; Lala DS; Singh SB
J Med Chem; 2014 Sep; 57(17):7182-205. PubMed ID: 24832115
[TBL] [Abstract][Full Text] [Related]
5. Differential expression and function of alternative splicing variants of human liver X receptor α.
Endo-Umeda K; Uno S; Fujimori K; Naito Y; Saito K; Yamagishi K; Jeong Y; Miyachi H; Tokiwa H; Yamada S; Makishima M
Mol Pharmacol; 2012 Jun; 81(6):800-10. PubMed ID: 22399489
[TBL] [Abstract][Full Text] [Related]
6. Liver x receptors regulate the transcriptional activity of the glucocorticoid receptor: implications for the carbohydrate metabolism.
Nader N; Ng SS; Wang Y; Abel BS; Chrousos GP; Kino T
PLoS One; 2012; 7(3):e26751. PubMed ID: 22457708
[TBL] [Abstract][Full Text] [Related]
7. Liver × receptor ligands disrupt breast cancer cell proliferation through an E2F-mediated mechanism.
Nguyen-Vu T; Vedin LL; Liu K; Jonsson P; Lin JZ; Candelaria NR; Candelaria LP; Addanki S; Williams C; Gustafsson JÅ; Steffensen KR; Lin CY
Breast Cancer Res; 2013 Jun; 15(3):R51. PubMed ID: 23809258
[TBL] [Abstract][Full Text] [Related]
8. Effects of ligand binding on the association properties and conformation in solution of retinoic acid receptors RXR and RAR.
Egea PF; Rochel N; Birck C; Vachette P; Timmins PA; Moras D
J Mol Biol; 2001 Mar; 307(2):557-76. PubMed ID: 11254382
[TBL] [Abstract][Full Text] [Related]
9. Ligand specificity and evolution of liver X receptors.
Reschly EJ; Ai N; Welsh WJ; Ekins S; Hagey LR; Krasowski MD
J Steroid Biochem Mol Biol; 2008 May; 110(1-2):83-94. PubMed ID: 18395439
[TBL] [Abstract][Full Text] [Related]
10. Simultaneous activation of the liver X receptors (LXRα and LXRβ) drives murine collagen-induced arthritis disease pathology.
Asquith DL; Miller AM; Reilly J; Kerr S; Welsh P; Sattar N; McInnes IB
Ann Rheum Dis; 2011 Dec; 70(12):2225-8. PubMed ID: 21859686
[TBL] [Abstract][Full Text] [Related]
11. The N-terminal nuclear localization sequences of liver X receptors alpha and beta bind to importin alpha and are essential for both nuclear import and transactivating functions.
Miller A; Crumbley C; Prüfer K
Int J Biochem Cell Biol; 2009 Apr; 41(4):834-43. PubMed ID: 18773967
[TBL] [Abstract][Full Text] [Related]
12. Molecular determinants of LXRalpha agonism.
Wang M; Thomas J; Burris TP; Schkeryantz J; Michael LF
J Mol Graph Model; 2003 Nov; 22(2):173-81. PubMed ID: 12932788
[TBL] [Abstract][Full Text] [Related]
13. Liver X receptor-retinoid X receptor (LXR-RXR) heterodimer cistrome reveals coordination of LXR and AP1 signaling in keratinocytes.
Shen Q; Bai Y; Chang KC; Wang Y; Burris TP; Freedman LP; Thompson CC; Nagpal S
J Biol Chem; 2011 Apr; 286(16):14554-63. PubMed ID: 21349840
[TBL] [Abstract][Full Text] [Related]
14. A novel liver X receptor agonist establishes species differences in the regulation of cholesterol 7alpha-hydroxylase (CYP7a).
Menke JG; Macnaul KL; Hayes NS; Baffic J; Chao YS; Elbrecht A; Kelly LJ; Lam MH; Schmidt A; Sahoo S; Wang J; Wright SD; Xin P; Zhou G; Moller DE; Sparrow CP
Endocrinology; 2002 Jul; 143(7):2548-58. PubMed ID: 12072387
[TBL] [Abstract][Full Text] [Related]
15. Endocytosis of LXRs: Signaling in liver and disease.
Brahma M; Ghosal S; Maruthi M; Kalangi SK
Prog Mol Biol Transl Sci; 2023; 194():347-375. PubMed ID: 36631198
[TBL] [Abstract][Full Text] [Related]
16. Miniaturization of cell-based beta-lactamase-dependent FRET assays to ultra-high throughput formats to identify agonists of human liver X receptors.
Chin J; Adams AD; Bouffard A; Green A; Lacson RG; Smith T; Fischer PA; Menke JG; Sparrow CP; Mitnaul LJ
Assay Drug Dev Technol; 2003 Dec; 1(6):777-87. PubMed ID: 15090224
[TBL] [Abstract][Full Text] [Related]
17. Computational studies of LXR molecular interactions reveal an allosteric communication pathway.
Burendahl S; Nilsson L
Proteins; 2012 Jan; 80(1):294-306. PubMed ID: 22072626
[TBL] [Abstract][Full Text] [Related]
18. Differential interactions of antiretroviral agents with LXR, ER and GR nuclear receptors: potential contributing factors to adverse events.
Svärd J; Blanco F; Nevin D; Fayne D; Mulcahy F; Hennessy M; Spiers JP
Br J Pharmacol; 2014 Jan; 171(2):480-97. PubMed ID: 24372550
[TBL] [Abstract][Full Text] [Related]
19. Recent progress in liver X receptor-selective modulators.
Ratni H; Wright MB
Curr Opin Drug Discov Devel; 2010 Jul; 13(4):403-13. PubMed ID: 20597026
[TBL] [Abstract][Full Text] [Related]
20. Therapeutic opportunities for liver X receptor modulators.
Collins JL
Curr Opin Drug Discov Devel; 2004 Sep; 7(5):692-702. PubMed ID: 15503871
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]