497 related articles for article (PubMed ID: 20391594)
21. Rapid detection and characterization of minor reactive metabolites using stable-isotope trapping in combination with tandem mass spectrometry.
Yan Z; Maher N; Torres R; Caldwell GW; Huebert N
Rapid Commun Mass Spectrom; 2005; 19(22):3322-30. PubMed ID: 16235238
[TBL] [Abstract][Full Text] [Related]
22. Rapid detection and characterization of in vitro and urinary N-acetyl-L-cysteine conjugates using quadrupole-linear ion trap mass spectrometry and polarity switching.
Jian W; Yao M; Zhang D; Zhu M
Chem Res Toxicol; 2009 Jul; 22(7):1246-55. PubMed ID: 19527004
[TBL] [Abstract][Full Text] [Related]
23. Identification and quantification of glutathione adducts of clozapine using ultra-high-performance liquid chromatography with orthogonal acceleration time-of-flight mass spectrometry and inductively coupled plasma mass spectrometry.
MacDonald C; Smith C; Michopoulos F; Weaver R; Wilson ID
Rapid Commun Mass Spectrom; 2011 Jul; 25(13):1787-93. PubMed ID: 21638353
[TBL] [Abstract][Full Text] [Related]
24. Evidence for the bioactivation of zomepirac and tolmetin by an oxidative pathway: identification of glutathione adducts in vitro in human liver microsomes and in vivo in rats.
Chen Q; Doss GA; Tung EC; Liu W; Tang YS; Braun MP; Didolkar V; Strauss JR; Wang RW; Stearns RA; Evans DC; Baillie TA; Tang W
Drug Metab Dispos; 2006 Jan; 34(1):145-51. PubMed ID: 16251255
[TBL] [Abstract][Full Text] [Related]
25. Prediction of in vivo potential for metabolic activation of drugs into chemically reactive intermediate: correlation of in vitro and in vivo generation of reactive intermediates and in vitro glutathione conjugate formation in rats and humans.
Masubuchi N; Makino C; Murayama N
Chem Res Toxicol; 2007 Mar; 20(3):455-64. PubMed ID: 17309281
[TBL] [Abstract][Full Text] [Related]
26. Rapid screening and characterization of drug metabolites using multiple ion monitoring dependent product ion scan and postacquisition data mining on a hybrid triple quadrupole-linear ion trap mass spectrometer.
Yao M; Ma L; Duchoslav E; Zhu M
Rapid Commun Mass Spectrom; 2009 Jun; 23(11):1683-93. PubMed ID: 19418486
[TBL] [Abstract][Full Text] [Related]
27. Atrazine metabolite screening in human microsomes: detection of novel reactive metabolites and glutathione adducts by LC-MS.
LeBlanc A; Sleno L
Chem Res Toxicol; 2011 Mar; 24(3):329-39. PubMed ID: 21361395
[TBL] [Abstract][Full Text] [Related]
28. Characterization of a highly sensitive and selective novel trapping reagent, stable isotope labeled glutathione ethyl ester, for the detection of reactive metabolites.
Yamaoka T; Kitamura Y
J Pharmacol Toxicol Methods; 2015; 76():83-95. PubMed ID: 26314789
[TBL] [Abstract][Full Text] [Related]
29. An algorithm for thorough background subtraction from high-resolution LC/MS data: application for detection of glutathione-trapped reactive metabolites.
Zhang H; Yang Y
J Mass Spectrom; 2008 Sep; 43(9):1181-90. PubMed ID: 18300330
[TBL] [Abstract][Full Text] [Related]
30. Detoxification of cytotoxic alpha,beta-unsaturated aldehydes by carnosine: characterization of conjugated adducts by electrospray ionization tandem mass spectrometry and detection by liquid chromatography/mass spectrometry in rat skeletal muscle.
Aldini G; Granata P; Carini M
J Mass Spectrom; 2002 Dec; 37(12):1219-28. PubMed ID: 12489081
[TBL] [Abstract][Full Text] [Related]
31. The development of a higher throughput reactive intermediate screening assay incorporating micro-bore liquid chromatography-micro-electrospray ionization-tandem mass spectrometry and glutathione ethyl ester as an in vitro conjugating agent.
Soglia JR; Harriman SP; Zhao S; Barberia J; Cole MJ; Boyd JG; Contillo LG
J Pharm Biomed Anal; 2004 Sep; 36(1):105-16. PubMed ID: 15351054
[TBL] [Abstract][Full Text] [Related]
32. Bioactivation of coumarin in rat olfactory mucosal microsomes: Detection of protein covalent binding and identification of reactive intermediates through analysis of glutathione adducts.
Zhuo X; Zhao W; Zheng J; Humphreys WG; Shu YZ; Zhu M
Chem Biol Interact; 2009 Oct; 181(2):227-35. PubMed ID: 19576871
[TBL] [Abstract][Full Text] [Related]
33. A fragmentation-based method for the differentiation of glutathione conjugates by high-resolution mass spectrometry with electrospray ionization.
Xie C; Zhong D; Chen X
Anal Chim Acta; 2013 Jul; 788():89-98. PubMed ID: 23845486
[TBL] [Abstract][Full Text] [Related]
34. A high-throughput liquid chromatography/tandem mass spectrometry method for screening glutathione conjugates using exact mass neutral loss acquisition.
Castro-Perez J; Plumb R; Liang L; Yang E
Rapid Commun Mass Spectrom; 2005; 19(6):798-804. PubMed ID: 15714601
[TBL] [Abstract][Full Text] [Related]
35. High-throughput screening and characterization of reactive metabolites using polarity switching of hybrid triple quadrupole linear ion trap mass spectrometry.
Wen B; Ma L; Nelson SD; Zhu M
Anal Chem; 2008 Mar; 80(5):1788-99. PubMed ID: 18251522
[TBL] [Abstract][Full Text] [Related]
36. Cyanide trapping of iminium ion reactive intermediates followed by detection and structure identification using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Argoti D; Liang L; Conteh A; Chen L; Bershas D; Yu CP; Vouros P; Yang E
Chem Res Toxicol; 2005 Oct; 18(10):1537-44. PubMed ID: 16533017
[TBL] [Abstract][Full Text] [Related]
37. 2,7-Disubstituted-pyrrolotriazine kinase inhibitors with an unusually high degree of reactive metabolite formation.
Wells-Knecht KJ; Ott GR; Cheng M; Wells GJ; Breslin HJ; Gingrich DE; Weinberg L; Mesaros EF; Huang Z; Yazdanian M; Ator MA; Aimone LD; Zeigler K; Dorsey BD
Chem Res Toxicol; 2011 Nov; 24(11):1994-2003. PubMed ID: 22023349
[TBL] [Abstract][Full Text] [Related]
38. Quantitation of glutathione by liquid chromatography/positive electrospray ionization tandem mass spectrometry.
Zhang F; Bartels MJ; Geter DR; Jeong YC; Schisler MR; Wood AJ; Kan L; Gollapudi BB
Rapid Commun Mass Spectrom; 2008 Nov; 22(22):3608-14. PubMed ID: 18937228
[TBL] [Abstract][Full Text] [Related]
39. A ferrocene-based reagent for the conjugation and quantification of reactive metabolites.
Jahn S; Lohmann W; Bomke S; Baumann A; Karst U
Anal Bioanal Chem; 2012 Jan; 402(1):461-71. PubMed ID: 21931954
[TBL] [Abstract][Full Text] [Related]
40. Determining protein adducts of fipexide: mass spectrometry based assay for confirming the involvement of its reactive metabolite in covalent binding.
Sleno L; Varesio E; Hopfgartner G
Rapid Commun Mass Spectrom; 2007; 21(24):4149-57. PubMed ID: 18022964
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
