BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1049 related articles for article (PubMed ID: 20395008)

  • 21. Polycomb repressive complex 2 is required for MLL-AF9 leukemia.
    Neff T; Sinha AU; Kluk MJ; Zhu N; Khattab MH; Stein L; Xie H; Orkin SH; Armstrong SA
    Proc Natl Acad Sci U S A; 2012 Mar; 109(13):5028-33. PubMed ID: 22396593
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Bmi1 cooperates with Dnmt1-associated protein 1 in gene silencing.
    Negishi M; Saraya A; Miyagi S; Nagao K; Inagaki Y; Nishikawa M; Tajima S; Koseki H; Tsuda H; Takasaki Y; Nakauchi H; Iwama A
    Biochem Biophys Res Commun; 2007 Feb; 353(4):992-8. PubMed ID: 17214966
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells.
    Ezhkova E; Pasolli HA; Parker JS; Stokes N; Su IH; Hannon G; Tarakhovsky A; Fuchs E
    Cell; 2009 Mar; 136(6):1122-35. PubMed ID: 19303854
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Polycomb-group oncogenes EZH2, BMI1, and RING1 are overexpressed in prostate cancer with adverse pathologic and clinical features.
    van Leenders GJ; Dukers D; Hessels D; van den Kieboom SW; Hulsbergen CA; Witjes JA; Otte AP; Meijer CJ; Raaphorst FM
    Eur Urol; 2007 Aug; 52(2):455-63. PubMed ID: 17134822
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma.
    Bruggeman SW; Hulsman D; Tanger E; Buckle T; Blom M; Zevenhoven J; van Tellingen O; van Lohuizen M
    Cancer Cell; 2007 Oct; 12(4):328-41. PubMed ID: 17936558
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locus.
    Tzatsos A; Pfau R; Kampranis SC; Tsichlis PN
    Proc Natl Acad Sci U S A; 2009 Feb; 106(8):2641-6. PubMed ID: 19202064
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Distinct expression of polycomb group proteins EZH2 and BMI1 in hepatocellular carcinoma.
    Yonemitsu Y; Imazeki F; Chiba T; Fukai K; Nagai Y; Miyagi S; Arai M; Aoki R; Miyazaki M; Nakatani Y; Iwama A; Yokosuka O
    Hum Pathol; 2009 Sep; 40(9):1304-11. PubMed ID: 19386347
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation.
    Chiba T; Zheng YW; Kita K; Yokosuka O; Saisho H; Onodera M; Miyoshi H; Nakano M; Zen Y; Nakanuma Y; Nakauchi H; Iwama A; Taniguchi H
    Gastroenterology; 2007 Sep; 133(3):937-50. PubMed ID: 17673212
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells.
    Majewski IJ; Ritchie ME; Phipson B; Corbin J; Pakusch M; Ebert A; Busslinger M; Koseki H; Hu Y; Smyth GK; Alexander WS; Hilton DJ; Blewitt ME
    Blood; 2010 Aug; 116(5):731-9. PubMed ID: 20445021
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Essential role for activation of the Polycomb group (PcG) protein chromatin silencing pathway in metastatic prostate cancer.
    Berezovska OP; Glinskii AB; Yang Z; Li XM; Hoffman RM; Glinsky GV
    Cell Cycle; 2006 Aug; 5(16):1886-901. PubMed ID: 16963837
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The transcriptional repressor NIPP1 is an essential player in EZH2-mediated gene silencing.
    Nuytten M; Beke L; Van Eynde A; Ceulemans H; Beullens M; Van Hummelen P; Fuks F; Bollen M
    Oncogene; 2008 Feb; 27(10):1449-60. PubMed ID: 17724462
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27.
    Kirmizis A; Bartley SM; Kuzmichev A; Margueron R; Reinberg D; Green R; Farnham PJ
    Genes Dev; 2004 Jul; 18(13):1592-605. PubMed ID: 15231737
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Loss of BAP1 function leads to EZH2-dependent transformation.
    LaFave LM; Béguelin W; Koche R; Teater M; Spitzer B; Chramiec A; Papalexi E; Keller MD; Hricik T; Konstantinoff K; Micol JB; Durham B; Knutson SK; Campbell JE; Blum G; Shi X; Doud EH; Krivtsov AV; Chung YR; Khodos I; de Stanchina E; Ouerfelli O; Adusumilli PS; Thomas PM; Kelleher NL; Luo M; Keilhack H; Abdel-Wahab O; Melnick A; Armstrong SA; Levine RL
    Nat Med; 2015 Nov; 21(11):1344-9. PubMed ID: 26437366
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The polycomb group protein BMI1 is a transcriptional target of HDAC inhibitors.
    Bommi PV; Dimri M; Sahasrabuddhe AA; Khandekar J; Dimri GP
    Cell Cycle; 2010 Jul; 9(13):2663-73. PubMed ID: 20543557
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells.
    Fiskus W; Pranpat M; Balasis M; Herger B; Rao R; Chinnaiyan A; Atadja P; Bhalla K
    Mol Cancer Ther; 2006 Dec; 5(12):3096-104. PubMed ID: 17172412
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Conditional activation of Bmi1 expression regulates self-renewal, apoptosis, and differentiation of neural stem/progenitor cells in vitro and in vivo.
    Yadirgi G; Leinster V; Acquati S; Bhagat H; Shakhova O; Marino S
    Stem Cells; 2011 Apr; 29(4):700-12. PubMed ID: 21305672
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Polycomb repressive complex 2 regulates normal development of the mouse heart.
    He A; Ma Q; Cao J; von Gise A; Zhou P; Xie H; Zhang B; Hsing M; Christodoulou DC; Cahan P; Daley GQ; Kong SW; Orkin SH; Seidman CE; Seidman JG; Pu WT
    Circ Res; 2012 Feb; 110(3):406-15. PubMed ID: 22158708
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Targeting of EZH2 to a defined genomic site is sufficient for recruitment of Dnmt3a but not de novo DNA methylation.
    Rush M; Appanah R; Lee S; Lam LL; Goyal P; Lorincz MC
    Epigenetics; 2009 Aug; 4(6):404-14. PubMed ID: 19717977
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes.
    Oguro H; Yuan J; Tanaka S; Miyagi S; Mochizuki-Kashio M; Ichikawa H; Yamazaki S; Koseki H; Nakauchi H; Iwama A
    J Exp Med; 2012 Mar; 209(3):445-54. PubMed ID: 22351929
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing.
    Cao R; Tsukada Y; Zhang Y
    Mol Cell; 2005 Dec; 20(6):845-54. PubMed ID: 16359901
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 53.