BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

512 related articles for article (PubMed ID: 20395365)

  • 1. Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6.
    Xu J; Sankaran VG; Ni M; Menne TF; Puram RV; Kim W; Orkin SH
    Genes Dev; 2010 Apr; 24(8):783-98. PubMed ID: 20395365
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Distinct Ldb1/NLI complexes orchestrate γ-globin repression and reactivation through ETO2 in human adult erythroid cells.
    Kiefer CM; Lee J; Hou C; Dale RK; Lee YT; Meier ER; Miller JL; Dean A
    Blood; 2011 Dec; 118(23):6200-8. PubMed ID: 22010104
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acyclovir induces fetal hemoglobin via downregulation of γ-globin repressors, BCL11A and SOX6 trans-acting factors.
    Ali H; Khan F; Ghulam Musharraf S
    Biochem Pharmacol; 2021 Aug; 190():114612. PubMed ID: 34010599
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Binding patterns of BCL11A in the globin and GATA1 loci and characterization of the BCL11A fetal hemoglobin locus.
    Jawaid K; Wahlberg K; Thein SL; Best S
    Blood Cells Mol Dis; 2010 Aug; 45(2):140-6. PubMed ID: 20542454
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mi2β-mediated silencing of the fetal γ-globin gene in adult erythroid cells.
    Amaya M; Desai M; Gnanapragasam MN; Wang SZ; Zu Zhu S; Williams DC; Ginder GD
    Blood; 2013 Apr; 121(17):3493-501. PubMed ID: 23444401
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NF-Y recruits both transcription activator and repressor to modulate tissue- and developmental stage-specific expression of human γ-globin gene.
    Zhu X; Wang Y; Pi W; Liu H; Wickrema A; Tuan D
    PLoS One; 2012; 7(10):e47175. PubMed ID: 23071749
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.
    Sankaran VG; Menne TF; Xu J; Akie TE; Lettre G; Van Handel B; Mikkola HK; Hirschhorn JN; Cantor AB; Orkin SH
    Science; 2008 Dec; 322(5909):1839-42. PubMed ID: 19056937
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Featured Article: Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs.
    Fornari TA; Lanaro C; Albuquerque DM; Ferreira R; Costa FF
    Exp Biol Med (Maywood); 2017 Feb; 242(3):267-274. PubMed ID: 27591578
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A.
    Xu J; Bauer DE; Kerenyi MA; Vo TD; Hou S; Hsu YJ; Yao H; Trowbridge JJ; Mandel G; Orkin SH
    Proc Natl Acad Sci U S A; 2013 Apr; 110(16):6518-23. PubMed ID: 23576758
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Intermediaries of branched chain amino acid metabolism induce fetal hemoglobin, and repress SOX6 and BCL11A, in definitive erythroid cells.
    Karkashon S; Raghupathy R; Bhatia H; Dutta A; Hess S; Higgs J; Tifft CJ; Little JA
    Blood Cells Mol Dis; 2015 Aug; 55(2):161-7. PubMed ID: 26142333
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Growth factor independence 1b (gfi1b) is important for the maturation of erythroid cells and the regulation of embryonic globin expression.
    Vassen L; Beauchemin H; Lemsaddek W; Krongold J; Trudel M; Möröy T
    PLoS One; 2014; 9(5):e96636. PubMed ID: 24800817
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
    Liu N; Hargreaves VV; Zhu Q; Kurland JV; Hong J; Kim W; Sher F; Macias-Trevino C; Rogers JM; Kurita R; Nakamura Y; Yuan GC; Bauer DE; Xu J; Bulyk ML; Orkin SH
    Cell; 2018 Apr; 173(2):430-442.e17. PubMed ID: 29606353
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.
    Roosjen M; McColl B; Kao B; Gearing LJ; Blewitt ME; Vadolas J
    FASEB J; 2014 Apr; 28(4):1610-20. PubMed ID: 24371119
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human globin knock-in mice complete fetal-to-adult hemoglobin switching in postnatal development.
    McConnell SC; Huo Y; Liu S; Ryan TM
    Mol Cell Biol; 2011 Feb; 31(4):876-83. PubMed ID: 21173165
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of adult levels of β-globin in human erythroid cells that intrinsically express embryonic or fetal globin by transduction with KLF1 and BCL11A-XL.
    Trakarnsanga K; Wilson MC; Lau W; Singleton BK; Parsons SF; Sakuntanaga P; Kurita R; Nakamura Y; Anstee DJ; Frayne J
    Haematologica; 2014 Nov; 99(11):1677-85. PubMed ID: 25107887
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multicolor staining of globin subtypes reveals impaired globin switching during erythropoiesis in human pluripotent stem cells.
    Ochi K; Takayama N; Hirose S; Nakahata T; Nakauchi H; Eto K
    Stem Cells Transl Med; 2014 Jul; 3(7):792-800. PubMed ID: 24873860
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice.
    Esteghamat F; Gillemans N; Bilic I; van den Akker E; Cantù I; van Gent T; Klingmüller U; van Lom K; von Lindern M; Grosveld F; Bryn van Dijk T; Busslinger M; Philipsen S
    Blood; 2013 Mar; 121(13):2553-62. PubMed ID: 23361909
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Developmental and species-divergent globin switching are driven by BCL11A.
    Sankaran VG; Xu J; Ragoczy T; Ippolito GC; Walkley CR; Maika SD; Fujiwara Y; Ito M; Groudine M; Bender MA; Tucker PW; Orkin SH
    Nature; 2009 Aug; 460(7259):1093-7. PubMed ID: 19657335
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element.
    Huang P; Keller CA; Giardine B; Grevet JD; Davies JOJ; Hughes JR; Kurita R; Nakamura Y; Hardison RC; Blobel GA
    Genes Dev; 2017 Aug; 31(16):1704-1713. PubMed ID: 28916711
    [TBL] [Abstract][Full Text] [Related]  

  • 20. KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching.
    Zhou D; Liu K; Sun CW; Pawlik KM; Townes TM
    Nat Genet; 2010 Sep; 42(9):742-4. PubMed ID: 20676097
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.