These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

68 related articles for article (PubMed ID: 2039582)

  • 1. Structure activity analysis of the formation of DNA damage induced in human tumor cells by the cyclodisone class of anti-tumor agent.
    Berardini MD; Pacheco DY; Gibson NW
    Anticancer Drug Des; 1991 May; 6(2):119-27. PubMed ID: 2039582
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of DNA damage and cytotoxicity induced in two human colon carcinoma cell lines by cyclodisone.
    Gibson NW
    Cancer Res; 1989 Jan; 49(1):154-7. PubMed ID: 2908842
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA reactivity and in vitro cytotoxicity of the novel antitumor agent 1,5,2,4-dioxadithiepane-2,2,4,4-tetraoxide (NSC-348948) in human embryo cells.
    Gibson NW; Hartley JA; Kohn KW
    Cancer Res; 1986 Apr; 46(4 Pt 1):1679-83. PubMed ID: 3509975
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparison of the in vitro cytotoxicity of cyclodisone with a series of structurally related analogues.
    Gibson NW
    Anticancer Drug Des; 1988 Dec; 3(3):199-204. PubMed ID: 3272138
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-activity study with bioreductive benzoquinone alkylating agents: effects on DT-diaphorase-mediated DNA crosslink and strand break formation in relation to mechanisms of cytotoxicity.
    Fourie J; Guziec F; Guziec L; Monterrosa C; Fiterman DJ; Begleiter A
    Cancer Chemother Pharmacol; 2004 Mar; 53(3):191-203. PubMed ID: 14614574
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparison of DNA interstrand cross-linking and strand breakage by 1,3-bis(2-chloroethyl)-1-nitrosourea in polyamine-depleted and control human adenocarcinoma cells.
    Seidenfeld J; Barnes D; Block AL; Erickson LC
    Cancer Res; 1987 Sep; 47(17):4538-43. PubMed ID: 3113720
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential cytotoxicity and DNA-damaging effects produced in human cells of the Mer+ and Mer- phenotypes by a series of 1-aryl-3-alkyltriazenes.
    Gibson NW; Hartley JA; LaFrance RJ; Vaughan K
    Cancer Res; 1986 Oct; 46(10):4999-5003. PubMed ID: 3756860
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytotoxic and DNA-damaging effects of 1,2-bis(sulfonyl)hydrazines on human cells of the Mer+ and Mer- phenotype.
    Pratviel G; Shyam K; Sartorelli AC
    Cancer Biochem Biophys; 1989 Oct; 10(4):365-75. PubMed ID: 2620294
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA damage and cytotoxicity of 2-chloroethyl (methylsulfonyl)methanesulfonate (NSC 338947) produced in human colon carcinoma cells with or without methylating agent pretreatment.
    Hartley JA; Gibson NW
    Cancer Res; 1986 Aug; 46(8):3871-5. PubMed ID: 3015378
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytotoxicity, DNA strand breakage and DNA-protein crosslinking by a novel transplatinum compound in human A2780 ovarian and MCF-7 breast carcinoma cells.
    Farrell N; Povirk LF; Dange Y; DeMasters G; Gupta MS; Kohlhagen G; Khan QA; Pommier Y; Gewirtz DA
    Biochem Pharmacol; 2004 Sep; 68(5):857-66. PubMed ID: 15294448
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 1: cellular pharmacology, in vitro and initial in vivo antitumor activity.
    Hartley JA; Spanswick VJ; Brooks N; Clingen PH; McHugh PJ; Hochhauser D; Pedley RB; Kelland LR; Alley MC; Schultz R; Hollingshead MG; Schweikart KM; Tomaszewski JE; Sausville EA; Gregson SJ; Howard PW; Thurston DE
    Cancer Res; 2004 Sep; 64(18):6693-9. PubMed ID: 15374986
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanisms of toxicity of hepsulfam in human tumor cell lines.
    Pacheco DY; Cook C; Hincks JR; Gibson NW
    Cancer Res; 1990 Dec; 50(23):7555-8. PubMed ID: 2253204
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Paradoxical increase in DNA cross-linking in a human ovarian carcinoma cell line resistant to cyanomorpholino doxorubicin.
    Lau DH; Ross KL; Sikic BI
    Cancer Res; 1990 Jul; 50(13):4056-60. PubMed ID: 2162251
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA damage induced by a new 2-chloroethyl nitrosourea on malignant melanoma cells.
    Godeneche D; Rapp M; Thierry A; Laval F; Madelmont JC; Chollet P; Veyre A
    Cancer Res; 1990 Sep; 50(18):5898-903. PubMed ID: 2393861
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cross-sensitivity to topoisomerase II inhibitors in cytotoxic drug-hypersensitive Chinese hamster ovary cell lines.
    Robson CN; Hoban PR; Harris AL; Hickson ID
    Cancer Res; 1987 Mar; 47(6):1560-5. PubMed ID: 2434220
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Relationships among cell survival, O6-alkylguanine-DNA alkyltransferase activity, and reactivation of methylated adenovirus 5 and herpes simplex virus type 1 in human melanoma cell lines.
    Maynard K; Parsons PG; Cerny T; Margison GP
    Cancer Res; 1989 Sep; 49(17):4813-7. PubMed ID: 2547518
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Application of DNA interstrand cross-link assay to estimate the sensitivity of tumor cells to alkylating agents].
    He T; Xia SX; Zhang YP
    Zhongguo Yao Li Xue Bao; 1990 Nov; 11(6):553-5. PubMed ID: 2130621
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytotoxicity and DNA damaging effects of a new nitrosourea, fotemustine, diethyl- 1-(3-(2-chloroethyl)-3-nitrosoureido) ethylphosphonate-S10036.
    Tapiero H; Yin MB; Catalin J; Paraire M; Deloffre P; Rustum Y; Bizzari JP; Tew KD
    Anticancer Res; 1989; 9(6):1617-22. PubMed ID: 2627116
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Linker length in podophyllotoxin-acridine conjugates determines potency in vivo and in vitro as well as specificity against MDR cell lines.
    Rothenborg-Jensen L; Hansen HF; Wessel I; Nitiss JL; Schmidt G; Jensen PB; Sehested M; Jensen LH
    Anticancer Drug Des; 2001 Dec; 16(6):305-15. PubMed ID: 12375883
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Topoisomerase II inhibition and altered kinetics of formation and repair of nitrosourea and cisplatin-induced DNA interstrand cross-links and cytotoxicity in human glioblastoma cells.
    Ali-Osman F; Berger MS; Rajagopal S; Spence A; Livingston RB
    Cancer Res; 1993 Dec; 53(23):5663-8. PubMed ID: 8242621
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.