These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

391 related articles for article (PubMed ID: 20400508)

  • 1. Enhancing antibody Fc heterodimer formation through electrostatic steering effects: applications to bispecific molecules and monovalent IgG.
    Gunasekaran K; Pentony M; Shen M; Garrett L; Forte C; Woodward A; Ng SB; Born T; Retter M; Manchulenko K; Sweet H; Foltz IN; Wittekind M; Yan W
    J Biol Chem; 2010 Jun; 285(25):19637-46. PubMed ID: 20400508
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel antibody engineering strategy for making monovalent bispecific heterodimeric IgG antibodies by electrostatic steering mechanism.
    Liu Z; Leng EC; Gunasekaran K; Pentony M; Shen M; Howard M; Stoops J; Manchulenko K; Razinkov V; Liu H; Fanslow W; Hu Z; Sun N; Hasegawa H; Clark R; Foltz IN; Yan W
    J Biol Chem; 2015 Mar; 290(12):7535-62. PubMed ID: 25583986
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A heterodimeric Fc-based bispecific antibody simultaneously targeting VEGFR-2 and Met exhibits potent antitumor activity.
    Choi HJ; Kim YJ; Lee S; Kim YS
    Mol Cancer Ther; 2013 Dec; 12(12):2748-59. PubMed ID: 24132142
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Immunoglobulin domain interface exchange as a platform technology for the generation of Fc heterodimers and bispecific antibodies.
    Skegro D; Stutz C; Ollier R; Svensson E; Wassmann P; Bourquin F; Monney T; Gn S; Blein S
    J Biol Chem; 2017 Jun; 292(23):9745-9759. PubMed ID: 28450393
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A new approach for generating bispecific antibodies based on a common light chain format and the stable architecture of human immunoglobulin G
    De Nardis C; Hendriks LJA; Poirier E; Arvinte T; Gros P; Bakker ABH; de Kruif J
    J Biol Chem; 2017 Sep; 292(35):14706-14717. PubMed ID: 28655766
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A rational approach to enhancing antibody Fc homodimer formation for robust production of antibody mixture in a single cell line.
    Yu J; Wang X; Xu T; Jin Q; Duan J; Wu J; Wu H; Xu T; Ye S
    J Biol Chem; 2017 Oct; 292(43):17885-17896. PubMed ID: 28878018
    [TBL] [Abstract][Full Text] [Related]  

  • 7. "BIClonals": Production of Bispecific Antibodies in IgG Format in Transiently Transfected Mammalian Cells.
    Litvak-Greenfeld D; Vaks L; Dror S; Nahary L; Benhar I
    Methods Mol Biol; 2019; 1904():431-454. PubMed ID: 30539485
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antiparallel conformation of knob and hole aglycosylated half-antibody homodimers is mediated by a CH2-CH3 hydrophobic interaction.
    Elliott JM; Ultsch M; Lee J; Tong R; Takeda K; Spiess C; Eigenbrot C; Scheer JM
    J Mol Biol; 2014 May; 426(9):1947-57. PubMed ID: 24576605
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Immunoglobulin Fc Heterodimer Platform Technology: From Design to Applications in Therapeutic Antibodies and Proteins.
    Ha JH; Kim JE; Kim YS
    Front Immunol; 2016; 7():394. PubMed ID: 27766096
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SEEDbodies: fusion proteins based on strand-exchange engineered domain (SEED) CH3 heterodimers in an Fc analogue platform for asymmetric binders or immunofusions and bispecific antibodies.
    Davis JH; Aperlo C; Li Y; Kurosawa E; Lan Y; Lo KM; Huston JS
    Protein Eng Des Sel; 2010 Apr; 23(4):195-202. PubMed ID: 20299542
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural differences between glycosylated, disulfide-linked heterodimeric Knob-into-Hole Fc fragment and its homodimeric Knob-Knob and Hole-Hole side products.
    Kuglstatter A; Stihle M; Neumann C; Müller C; Schaefer W; Klein C; Benz J;
    Protein Eng Des Sel; 2017 Sep; 30(9):649-656. PubMed ID: 28985438
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis of a novel heterodimeric Fc for bispecific antibody production.
    Wei H; Cai H; Jin Y; Wang P; Zhang Q; Lin Y; Wang W; Cheng J; Zeng N; Xu T; Zhou A
    Oncotarget; 2017 Aug; 8(31):51037-51049. PubMed ID: 28881627
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Single variable domain-IgG fusion. A novel recombinant approach to Fc domain-containing bispecific antibodies.
    Shen J; Vil MD; Jimenez X; Iacolina M; Zhang H; Zhu Z
    J Biol Chem; 2006 Apr; 281(16):10706-14. PubMed ID: 16481314
    [TBL] [Abstract][Full Text] [Related]  

  • 14. LC-MS characterization and purity assessment of a prototype bispecific antibody.
    Woods RJ; Xie MH; Von Kreudenstein TS; Ng GY; Dixit SB
    MAbs; 2013; 5(5):711-22. PubMed ID: 23884083
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
    Lewis SM; Wu X; Pustilnik A; Sereno A; Huang F; Rick HL; Guntas G; Leaver-Fay A; Smith EM; Ho C; Hansen-Estruch C; Chamberlain AK; Truhlar SM; Conner EM; Atwell S; Kuhlman B; Demarest SJ
    Nat Biotechnol; 2014 Feb; 32(2):191-8. PubMed ID: 24463572
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A single mutation increases heavy-chain heterodimer assembly of bispecific antibodies by inducing structural disorder in one homodimer species.
    Stutz C; Blein S
    J Biol Chem; 2020 Jul; 295(28):9392-9408. PubMed ID: 32404368
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Improving target cell specificity using a novel monovalent bispecific IgG design.
    Mazor Y; Oganesyan V; Yang C; Hansen A; Wang J; Liu H; Sachsenmeier K; Carlson M; Gadre DV; Borrok MJ; Yu XQ; Dall'Acqua W; Wu H; Chowdhury PS
    MAbs; 2015; 7(2):377-89. PubMed ID: 25621507
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C
    Bagert JD; Oganesyan V; Chiang CI; Iannotti M; Lin J; Yang C; Payne S; McMahon W; Edwards S; Dippel A; Hutchinson M; Huang F; Aleti V; Niu C; Qian C; Denham J; Ferreira S; Pradhan P; Penney M; Wang C; Liu W; Walseng E; Mazor Y
    MAbs; 2023; 15(1):2273449. PubMed ID: 37930310
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Computationally Designed Bispecific Antibodies using Negative State Repertoires.
    Leaver-Fay A; Froning KJ; Atwell S; Aldaz H; Pustilnik A; Lu F; Huang F; Yuan R; Hassanali S; Chamberlain AK; Fitchett JR; Demarest SJ; Kuhlman B
    Structure; 2016 Apr; 24(4):641-651. PubMed ID: 26996964
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bispecific human IgG by design.
    Carter P
    J Immunol Methods; 2001 Feb; 248(1-2):7-15. PubMed ID: 11223065
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.