These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

103 related articles for article (PubMed ID: 20403428)

  • 1. Sphingosine and FTY720 directly bind pro-survival 14-3-3 proteins to regulate their function.
    Woodcock JM; Ma Y; Coolen C; Pham D; Jones C; Lopez AF; Pitson SM
    Cell Signal; 2010 Sep; 22(9):1291-9. PubMed ID: 20403428
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Essential requirement for sphingosine kinase 2 in a sphingolipid apoptosis pathway activated by FTY720 analogues.
    Don AS; Martinez-Lamenca C; Webb WR; Proia RL; Roberts E; Rosen H
    J Biol Chem; 2007 May; 282(21):15833-42. PubMed ID: 17400555
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular targets of FTY720 (fingolimod).
    Pitman MR; Woodcock JM; Lopez AF; Pitson SM
    Curr Mol Med; 2012 Dec; 12(10):1207-19. PubMed ID: 22834825
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of phosphorylation of immunomodulatory agent FTY720 (fingolimod) on antiproliferative activity against breast and colon cancer cells.
    Nagaoka Y; Otsuki K; Fujita T; Uesato S
    Biol Pharm Bull; 2008 Jun; 31(6):1177-81. PubMed ID: 18520051
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FTY720 (fingolimod) sensitizes prostate cancer cells to radiotherapy by inhibition of sphingosine kinase-1.
    Pchejetski D; Bohler T; Brizuela L; Sauer L; Doumerc N; Golzio M; Salunkhe V; Teissié J; Malavaud B; Waxman J; Cuvillier O
    Cancer Res; 2010 Nov; 70(21):8651-61. PubMed ID: 20959468
    [TBL] [Abstract][Full Text] [Related]  

  • 6. (R)-FTY720 methyl ether is a specific sphingosine kinase 2 inhibitor: Effect on sphingosine kinase 2 expression in HEK 293 cells and actin rearrangement and survival of MCF-7 breast cancer cells.
    Lim KG; Sun C; Bittman R; Pyne NJ; Pyne S
    Cell Signal; 2011 Oct; 23(10):1590-5. PubMed ID: 21620961
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2.
    Paugh SW; Payne SG; Barbour SE; Milstien S; Spiegel S
    FEBS Lett; 2003 Nov; 554(1-2):189-93. PubMed ID: 14596938
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells.
    Tonelli F; Lim KG; Loveridge C; Long J; Pitson SM; Tigyi G; Bittman R; Pyne S; Pyne NJ
    Cell Signal; 2010 Oct; 22(10):1536-42. PubMed ID: 20570726
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cis-4-methylsphingosine is a sphingosine-1-phosphate receptor modulator.
    Ter Braak M; Claas RF; Hegen B; Labocha S; Ferreirós N; Pfeilschifter J; Huwiler A; van Echten-Deckert G; Meyer Zu Heringdorf D
    Biochem Pharmacol; 2011 Mar; 81(5):617-25. PubMed ID: 21163254
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FTY720 inhibits tumor growth and enhances the tumor-suppressive effect of topotecan in neuroblastoma by interfering with the sphingolipid signaling pathway.
    Li MH; Hla T; Ferrer F
    Pediatr Blood Cancer; 2013 Sep; 60(9):1418-23. PubMed ID: 23704073
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FTY720 induces apoptosis in hepatocellular carcinoma cells through activation of protein kinase C delta signaling.
    Hung JH; Lu YS; Wang YC; Ma YH; Wang DS; Kulp SK; Muthusamy N; Byrd JC; Cheng AL; Chen CS
    Cancer Res; 2008 Feb; 68(4):1204-12. PubMed ID: 18281497
    [TBL] [Abstract][Full Text] [Related]  

  • 12. FTY720 analogues as sphingosine kinase 1 inhibitors: enzyme inhibition kinetics, allosterism, proteasomal degradation, and actin rearrangement in MCF-7 breast cancer cells.
    Lim KG; Tonelli F; Li Z; Lu X; Bittman R; Pyne S; Pyne NJ
    J Biol Chem; 2011 May; 286(21):18633-40. PubMed ID: 21464128
    [TBL] [Abstract][Full Text] [Related]  

  • 13. FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: a protective role of autophagy.
    Zhang N; Qi Y; Wadham C; Wang L; Warren A; Di W; Xia P
    Autophagy; 2010 Nov; 6(8):1157-67. PubMed ID: 20935520
    [TBL] [Abstract][Full Text] [Related]  

  • 14. FTY720 and cisplatin synergistically induce the death of cisplatin-resistant melanoma cells through the downregulation of the PI3K pathway and the decrease in epidermal growth factor receptor expression.
    Ishitsuka A; Fujine E; Mizutani Y; Tawada C; Kanoh H; Banno Y; Seishima M
    Int J Mol Med; 2014 Oct; 34(4):1169-74. PubMed ID: 25109763
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Involvement of vacuolar H(+)-ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720.
    Tay KH; Liu X; Chi M; Jin L; Jiang CC; Guo ST; Verrills NM; Tseng HY; Zhang XD
    Pigment Cell Melanoma Res; 2015 Mar; 28(2):171-83. PubMed ID: 25358761
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sphingosine mediates FTY720-induced apoptosis in LLC-PK1 cells.
    Lee WJ; Yoo HS; Suh PG; Oh S; Lim JS; Lee YM
    Exp Mol Med; 2004 Oct; 36(5):420-7. PubMed ID: 15557814
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sphingosine analog fingolimod (FTY720) increases radiation sensitivity of human breast cancer cells in vitro.
    Marvaso G; Barone A; Amodio N; Raimondi L; Agosti V; Altomare E; Scotti V; Lombardi A; Bianco R; Bianco C; Caraglia M; Tassone P; Tagliaferri P
    Cancer Biol Ther; 2014 Jun; 15(6):797-805. PubMed ID: 24657936
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Immunomodulator FTY720 induces myofibroblast differentiation via the lysophospholipid receptor S1P3 and Smad3 signaling.
    Keller CD; Rivera Gil P; Tölle M; van der Giet M; Chun J; Radeke HH; Schäfer-Korting M; Kleuser B
    Am J Pathol; 2007 Jan; 170(1):281-92. PubMed ID: 17200201
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The immune modulator FTY720 targets sphingosine 1-phosphate receptors.
    Brinkmann V; Davis MD; Heise CE; Albert R; Cottens S; Hof R; Bruns C; Prieschl E; Baumruker T; Hiestand P; Foster CA; Zollinger M; Lynch KR
    J Biol Chem; 2002 Jun; 277(24):21453-7. PubMed ID: 11967257
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The immune modulator FTY720 targets sphingosine-kinase-dependent migration of human monocytes in response to amyloid beta-protein and its precursor.
    Kaneider NC; Lindner J; Feistritzer C; Sturn DH; Mosheimer BA; Djanani AM; Wiedermann CJ
    FASEB J; 2004 Aug; 18(11):1309-11. PubMed ID: 15208267
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.