BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

241 related articles for article (PubMed ID: 20404329)

  • 1. Mutation-dependent polymorphism of Cu,Zn-superoxide dismutase aggregates in the familial form of amyotrophic lateral sclerosis.
    Furukawa Y; Kaneko K; Yamanaka K; Nukina N
    J Biol Chem; 2010 Jul; 285(29):22221-31. PubMed ID: 20404329
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Common dynamical signatures of familial amyotrophic lateral sclerosis-associated structurally diverse Cu, Zn superoxide dismutase mutants.
    Khare SD; Dokholyan NV
    Proc Natl Acad Sci U S A; 2006 Feb; 103(9):3147-52. PubMed ID: 16488975
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Wild-type Cu/Zn superoxide dismutase (SOD1) does not facilitate, but impedes the formation of protein aggregates of amyotrophic lateral sclerosis causing mutant SOD1.
    Witan H; Gorlovoy P; Kaya AM; Koziollek-Drechsler I; Neumann H; Behl C; Clement AM
    Neurobiol Dis; 2009 Nov; 36(2):331-42. PubMed ID: 19660548
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inducible superoxide dismutase 1 aggregation in transgenic amyotrophic lateral sclerosis mouse fibroblasts.
    Turner BJ; Lopes EC; Cheema SS
    J Cell Biochem; 2004 Apr; 91(5):1074-84. PubMed ID: 15034941
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural changes to monomeric CuZn superoxide dismutase caused by the familial amyotrophic lateral sclerosis-associated mutation A4V.
    Schmidlin T; Kennedy BK; Daggett V
    Biophys J; 2009 Sep; 97(6):1709-18. PubMed ID: 19751676
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural instability and Cu-dependent pro-oxidant activity acquired by the apo form of mutant SOD1 associated with amyotrophic lateral sclerosis.
    Kitamura F; Fujimaki N; Okita W; Hiramatsu H; Takeuchi H
    Biochemistry; 2011 May; 50(20):4242-50. PubMed ID: 21506602
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural similarity of wild-type and ALS-mutant superoxide dismutase-1 fibrils using limited proteolysis and atomic force microscopy.
    Chan PK; Chattopadhyay M; Sharma S; Souda P; Gralla EB; Borchelt DR; Whitelegge JP; Valentine JS
    Proc Natl Acad Sci U S A; 2013 Jul; 110(27):10934-9. PubMed ID: 23781106
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An examination of wild-type SOD1 in modulating the toxicity and aggregation of ALS-associated mutant SOD1.
    Prudencio M; Durazo A; Whitelegge JP; Borchelt DR
    Hum Mol Genet; 2010 Dec; 19(24):4774-89. PubMed ID: 20871097
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis.
    Auclair JR; Boggio KJ; Petsko GA; Ringe D; Agar JN
    Proc Natl Acad Sci U S A; 2010 Dec; 107(50):21394-9. PubMed ID: 21098299
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure, folding, and misfolding of Cu,Zn superoxide dismutase in amyotrophic lateral sclerosis.
    Rakhit R; Chakrabartty A
    Biochim Biophys Acta; 2006; 1762(11-12):1025-37. PubMed ID: 16814528
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Superoxide dismutase 1 encoding mutations linked to ALS adopts a spectrum of misfolded states.
    Prudencio M; Borchelt DR
    Mol Neurodegener; 2011 Nov; 6():77. PubMed ID: 22094223
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An intersubunit disulfide bond prevents in vitro aggregation of a superoxide dismutase-1 mutant linked to familial amytrophic lateral sclerosis.
    Ray SS; Nowak RJ; Strokovich K; Brown RH; Walz T; Lansbury PT
    Biochemistry; 2004 May; 43(17):4899-905. PubMed ID: 15109247
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Copper chaperone for superoxide dismutase co-aggregates with superoxide dismutase 1 (SOD1) in neuronal Lewy body-like hyaline inclusions: an immunohistochemical study on familial amyotrophic lateral sclerosis with SOD1 gene mutation.
    Kato S; Sumi-Akamaru H; Fujimura H; Sakoda S; Kato M; Hirano A; Takikawa M; Ohama E
    Acta Neuropathol; 2001 Sep; 102(3):233-8. PubMed ID: 11585247
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis.
    Furukawa Y; Kaneko K; Yamanaka K; O'Halloran TV; Nukina N
    J Biol Chem; 2008 Aug; 283(35):24167-76. PubMed ID: 18552350
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dimerization, oligomerization, and aggregation of human amyotrophic lateral sclerosis copper/zinc superoxide dismutase 1 protein mutant forms in live cells.
    Kim J; Lee H; Lee JH; Kwon DY; Genovesio A; Fenistein D; Ogier A; Brondani V; Grailhe R
    J Biol Chem; 2014 May; 289(21):15094-103. PubMed ID: 24692554
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Local unfolding of Cu, Zn superoxide dismutase monomer determines the morphology of fibrillar aggregates.
    Ding F; Furukawa Y; Nukina N; Dokholyan NV
    J Mol Biol; 2012 Aug; 421(4-5):548-60. PubMed ID: 22210350
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Small-molecule-mediated stabilization of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants against unfolding and aggregation.
    Ray SS; Nowak RJ; Brown RH; Lansbury PT
    Proc Natl Acad Sci U S A; 2005 Mar; 102(10):3639-44. PubMed ID: 15738401
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutant superoxide dismutase 1 forms aggregates in the brain mitochondrial matrix of amyotrophic lateral sclerosis mice.
    Vijayvergiya C; Beal MF; Buck J; Manfredi G
    J Neurosci; 2005 Mar; 25(10):2463-70. PubMed ID: 15758154
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of metal ions, disulfide reduction and mutations related to familial ALS promote formation of amyloid-like aggregates from superoxide dismutase.
    Oztug Durer ZA; Cohlberg JA; Dinh P; Padua S; Ehrenclou K; Downes S; Tan JK; Nakano Y; Bowman CJ; Hoskins JL; Kwon C; Mason AZ; Rodriguez JA; Doucette PA; Shaw BF; Valentine JS
    PLoS One; 2009; 4(3):e5004. PubMed ID: 19325915
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis.
    Valentine JS; Doucette PA; Zittin Potter S
    Annu Rev Biochem; 2005; 74():563-93. PubMed ID: 15952898
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.