198 related articles for article (PubMed ID: 20405344)
1. Modulation of cholesterol, farnesylpyrophosphate, and geranylgeranylpyrophosphate in neuroblastoma SH-SY5Y-APP695 cells: impact on amyloid beta-protein production.
Hooff GP; Peters I; Wood WG; Müller WE; Eckert GP
Mol Neurobiol; 2010 Jun; 41(2-3):341-50. PubMed ID: 20405344
[TBL] [Abstract][Full Text] [Related]
2. Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients.
Eckert GP; Hooff GP; Strandjord DM; Igbavboa U; Volmer DA; Müller WE; Wood WG
Neurobiol Dis; 2009 Aug; 35(2):251-7. PubMed ID: 19464372
[TBL] [Abstract][Full Text] [Related]
3. Isoprenoids, small GTPases and Alzheimer's disease.
Hooff GP; Wood WG; Müller WE; Eckert GP
Biochim Biophys Acta; 2010 Aug; 1801(8):896-905. PubMed ID: 20382260
[TBL] [Abstract][Full Text] [Related]
4. Brain isoprenoids farnesyl pyrophosphate and geranylgeranyl pyrophosphate are increased in aged mice.
Hooff GP; Wood WG; Kim JH; Igbavboa U; Ong WY; Muller WE; Eckert GP
Mol Neurobiol; 2012 Aug; 46(1):179-85. PubMed ID: 22692983
[TBL] [Abstract][Full Text] [Related]
5. Effects of farnesyl pyrophosphate accumulation on calvarial osteoblast differentiation.
Weivoda MM; Hohl RJ
Endocrinology; 2011 Aug; 152(8):3113-22. PubMed ID: 21586555
[TBL] [Abstract][Full Text] [Related]
6. Key Enzymes for the Mevalonate Pathway in the Cardiovascular System.
Zhang C; Jin DD; Wang XY; Lou L; Yang J
J Cardiovasc Pharmacol; 2021 Feb; 77(2):142-152. PubMed ID: 33538531
[TBL] [Abstract][Full Text] [Related]
7. Statins inhibit blastocyst formation by preventing geranylgeranylation.
Alarcon VB; Marikawa Y
Mol Hum Reprod; 2016 May; 22(5):350-63. PubMed ID: 26908642
[TBL] [Abstract][Full Text] [Related]
8. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors attenuate beta-amyloid-induced microglial inflammatory responses.
Cordle A; Landreth G
J Neurosci; 2005 Jan; 25(2):299-307. PubMed ID: 15647473
[TBL] [Abstract][Full Text] [Related]
9. Mevalonate Cascade and its Regulation in Cholesterol Metabolism in Different Tissues in Health and Disease.
Hashemi M; Hoshyar R; Ande SR; Chen QM; Solomon C; Zuse A; Naderi M
Curr Mol Pharmacol; 2017; 10(1):13-26. PubMed ID: 26758949
[TBL] [Abstract][Full Text] [Related]
10. Isoprenoid pyrophosphate analogues regulate expression of Ras-related proteins.
Holstein SA; Wohlford-Lenane CL; Wiemer DF; Hohl RJ
Biochemistry; 2003 Apr; 42(15):4384-91. PubMed ID: 12693933
[TBL] [Abstract][Full Text] [Related]
11. Huperzine A regulates amyloid precursor protein processing via protein kinase C and mitogen-activated protein kinase pathways in neuroblastoma SK-N-SH cells over-expressing wild type human amyloid precursor protein 695.
Peng Y; Lee DY; Jiang L; Ma Z; Schachter SC; Lemere CA
Neuroscience; 2007 Dec; 150(2):386-95. PubMed ID: 17945434
[TBL] [Abstract][Full Text] [Related]
12. A rapid and sensitive assay for determining human brain levels of farnesyl-(FPP) and geranylgeranylpyrophosphate (GGPP) and transferase activities using UHPLC-MS/MS.
Hooff GP; Patel N; Wood WG; Müller WE; Eckert GP; Volmer DA
Anal Bioanal Chem; 2010 Oct; 398(4):1801-8. PubMed ID: 20730526
[TBL] [Abstract][Full Text] [Related]
13. Simvastatin inhibits the migration and adhesion of monocytic cells and disorganizes the cytoskeleton of activated endothelial cells.
Pozo M; de Nicolás R; Egido J; González-Cabrero J
Eur J Pharmacol; 2006 Oct; 548(1-3):53-63. PubMed ID: 16973154
[TBL] [Abstract][Full Text] [Related]
14. Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells.
Alizadeh J; Zeki AA; Mirzaei N; Tewary S; Rezaei Moghadam A; Glogowska A; Nagakannan P; Eftekharpour E; Wiechec E; Gordon JW; Xu FY; Field JT; Yoneda KY; Kenyon NJ; Hashemi M; Hatch GM; Hombach-Klonisch S; Klonisch T; Ghavami S
Sci Rep; 2017 Mar; 7():44841. PubMed ID: 28344327
[TBL] [Abstract][Full Text] [Related]
15. Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis.
Wood WG; Li L; Müller WE; Eckert GP
J Neurochem; 2014 May; 129(4):559-72. PubMed ID: 24329875
[TBL] [Abstract][Full Text] [Related]
16. Activated human microglia stimulate neuroblastoma cells to upregulate production of beta amyloid protein and tau: implications for Alzheimer's disease pathogenesis.
Lee M; McGeer E; McGeer PL
Neurobiol Aging; 2015 Jan; 36(1):42-52. PubMed ID: 25169677
[TBL] [Abstract][Full Text] [Related]
17. Effect of pravastatin on type IV collagen secretion and mesangial cell proliferation.
Nishimura M; Tanaka T; Yasuda T; Kurakata S; Kitagawa M; Yamada K; Saito Y; Hirai A
Kidney Int Suppl; 1999 Jul; 71():S97-100. PubMed ID: 10412748
[TBL] [Abstract][Full Text] [Related]
18. Aβ-Induced Insulin Resistance and the Effects of Insulin on the Cholesterol Synthesis Pathway and Aβ Secretion in Neural Cells.
Najem D; Bamji-Mirza M; Yang Z; Zhang W
Neurosci Bull; 2016 Jun; 32(3):227-38. PubMed ID: 27207326
[TBL] [Abstract][Full Text] [Related]
19. Isoprenoids and tau pathology in sporadic Alzheimer's disease.
Pelleieux S; Picard C; Lamarre-Théroux L; Dea D; Leduc V; Tsantrizos YS; Poirier J
Neurobiol Aging; 2018 May; 65():132-139. PubMed ID: 29476987
[TBL] [Abstract][Full Text] [Related]
20. Statins cause intracellular accumulation of amyloid precursor protein, beta-secretase-cleaved fragments, and amyloid beta-peptide via an isoprenoid-dependent mechanism.
Cole SL; Grudzien A; Manhart IO; Kelly BL; Oakley H; Vassar R
J Biol Chem; 2005 May; 280(19):18755-70. PubMed ID: 15718241
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]