BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

316 related articles for article (PubMed ID: 20406211)

  • 1. Electrophysiological effects of the anti-cancer drug lapatinib on cardiac repolarization.
    Lee HA; Kim EJ; Hyun SA; Park SG; Kim KS
    Basic Clin Pharmacol Toxicol; 2010 Jul; 107(1):614-8. PubMed ID: 20406211
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cellular mechanism of the QT prolongation induced by sulpiride.
    Lee HA; Kim KS; Park SJ; Kim EJ
    Int J Toxicol; 2009; 28(3):207-12. PubMed ID: 19546258
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cardiac glycosides as novel inhibitors of human ether-a-go-go-related gene channel trafficking.
    Wang L; Wible BA; Wan X; Ficker E
    J Pharmacol Exp Ther; 2007 Feb; 320(2):525-34. PubMed ID: 17095614
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Electrophysiological mechanisms of vandetanib-induced cardiotoxicity: Comparison of action potentials in rabbit Purkinje fibers and pluripotent stem cell-derived cardiomyocytes.
    Lee HA; Hyun SA; Byun B; Chae JH; Kim KS
    PLoS One; 2018; 13(4):e0195577. PubMed ID: 29630634
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.
    Davie C; Pierre-Valentin J; Pollard C; Standen N; Mitcheson J; Alexander P; Thong B
    J Cardiovasc Electrophysiol; 2004 Nov; 15(11):1302-9. PubMed ID: 15574182
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD-307243) causes instantaneous current through human ether-a-go-go-related gene potassium channels.
    Gordon E; Lozinskaya IM; Lin Z; Semus SF; Blaney FE; Willette RN; Xu X
    Mol Pharmacol; 2008 Mar; 73(3):639-51. PubMed ID: 18042732
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transfection by eukaryotic expression vector pcDNA3-HERG inhibits the cultured neonatal rabbit ventricular myocyte hypertrophy induced by phenylephrine.
    Zhao Y; Xu Y; Cui C; Li Y; Zeng Y
    Cardiovasc Pathol; 2012; 21(4):339-45. PubMed ID: 22100990
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Electrophysiologic characterization of a novel hERG channel activator.
    Su Z; Limberis J; Souers A; Kym P; Mikhail A; Houseman K; Diaz G; Liu X; Martin RL; Cox BF; Gintant GA
    Biochem Pharmacol; 2009 Apr; 77(8):1383-90. PubMed ID: 19426677
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chronic probucol treatment decreases the slow component of the delayed-rectifier potassium current in CHO cells transfected with KCNQ1 and KCNE1: a novel mechanism of QT prolongation.
    Taniguchi T; Uesugi M; Arai T; Yoshinaga T; Miyamoto N; Sawada K
    J Cardiovasc Pharmacol; 2012 Apr; 59(4):377-86. PubMed ID: 22189896
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In-vitro experimental models for the risk assessment of antibiotic-induced QT prolongation.
    Lu HR; Vlaminckx E; Van de Water A; Rohrbacher J; Hermans A; Gallacher DJ
    Eur J Pharmacol; 2006 Dec; 553(1-3):229-39. PubMed ID: 17054943
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Diabetes mellitus attenuates the repolarization reserve in mammalian heart.
    Lengyel C; Virág L; Bíró T; Jost N; Magyar J; Biliczki P; Kocsis E; Skoumal R; Nánási PP; Tóth M; Kecskeméti V; Papp JG; Varró A
    Cardiovasc Res; 2007 Feb; 73(3):512-20. PubMed ID: 17182020
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Galantamine (Reminyl) delays cardiac ventricular repolarization and prolongs the QT interval by blocking the HERG current.
    Vigneault P; Bourgault S; Kaddar N; Caillier B; Pilote S; Patoine D; Simard C; Drolet B
    Eur J Pharmacol; 2012 Apr; 681(1-3):68-74. PubMed ID: 22366430
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The neuroprotective agent sipatrigine blocks multiple cardiac ion channels and causes triangulation of the ventricular action potential.
    Gao Z; Milnes JT; Choisy SC; Leach MJ; Hancox JC; James AF
    Clin Exp Pharmacol Physiol; 2005 Dec; 32(12):1088-96. PubMed ID: 16445575
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Apico-basal inhomogeneity in distribution of ion channels in canine and human ventricular myocardium.
    Szentadrassy N; Banyasz T; Biro T; Szabo G; Toth BI; Magyar J; Lazar J; Varro A; Kovacs L; Nanasi PP
    Cardiovasc Res; 2005 Mar; 65(4):851-60. PubMed ID: 15721865
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional effects of the late sodium current inhibition by AZD7009 and lidocaine in rabbit isolated atrial and ventricular tissue and Purkinje fibre.
    Persson F; Andersson B; Duker G; Jacobson I; Carlsson L
    Eur J Pharmacol; 2007 Mar; 558(1-3):133-43. PubMed ID: 17198698
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of antipsychotic drugs on I(to), I (Na), I (sus), I (K1), and hERG: QT prolongation, structure activity relationship, and network analysis.
    Crumb WJ; Ekins S; Sarazan RD; Wikel JH; Wrighton SA; Carlson C; Beasley CM
    Pharm Res; 2006 Jun; 23(6):1133-43. PubMed ID: 16715368
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of a neuroprotective drug, eliprodil on cardiac repolarisation: importance of the decreased repolarisation reserve in the development of proarrhythmic risk.
    Lengyel C; Dézsi L; Biliczki P; Horváth C; Virág L; Iost N; Németh M; Tálosi L; Papp JG; Varró A
    Br J Pharmacol; 2004 Sep; 143(1):152-8. PubMed ID: 15302678
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacology of cardiac potassium channels.
    Li GR; Dong MQ
    Adv Pharmacol; 2010; 59():93-134. PubMed ID: 20933200
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Additive effects of ziprasidone and D,L-sotalol on the action potential in rabbit Purkinje fibres and on the hERG potassium current.
    Ducroq J; Printemps R; Le Grand M
    J Pharmacol Toxicol Methods; 2005; 52(1):115-22. PubMed ID: 15922632
    [TBL] [Abstract][Full Text] [Related]  

  • 20. QTc shortening with a new investigational cancer drug: a brief case study.
    Himmel HM; Hoffmann M
    J Pharmacol Toxicol Methods; 2010; 62(1):72-81. PubMed ID: 20570746
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.