BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

445 related articles for article (PubMed ID: 20406823)

  • 1. Oxazolomycin biosynthesis in Streptomyces albus JA3453 featuring an "acyltransferase-less" type I polyketide synthase that incorporates two distinct extender units.
    Zhao C; Coughlin JM; Ju J; Zhu D; Wendt-Pienkowski E; Zhou X; Wang Z; Shen B; Deng Z
    J Biol Chem; 2010 Jun; 285(26):20097-108. PubMed ID: 20406823
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning the oxazolomycin biosynthetic gene cluster from Streptomyces albus JA3453.
    Zhao C; Ju J; Christenson SD; Smith WC; Song D; Zhou X; Shen B; Deng Z
    J Bacteriol; 2006 Jun; 188(11):4142-7. PubMed ID: 16707707
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.
    Dunn BJ; Watts KR; Robbins T; Cane DE; Khosla C
    Biochemistry; 2014 Jun; 53(23):3796-806. PubMed ID: 24871074
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Supramolecular templating in kirromycin biosynthesis: the acyltransferase KirCII loads ethylmalonyl-CoA extender onto a specific ACP of the trans-AT PKS.
    Musiol EM; Härtner T; Kulik A; Moldenhauer J; Piel J; Wohlleben W; Weber T
    Chem Biol; 2011 Apr; 18(4):438-44. PubMed ID: 21513880
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural and Biochemical Insight into the Recruitment of Acyl Carrier Protein-Linked Extender Units in Ansamitocin Biosynthesis.
    Zhang F; Ji H; Ali I; Deng Z; Bai L; Zheng J
    Chembiochem; 2020 May; 21(9):1309-1314. PubMed ID: 31777147
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of biosynthetic gene cluster for the production of virginiamycin M, a streptogramin type A antibiotic, in Streptomyces virginiae.
    Pulsawat N; Kitani S; Nihira T
    Gene; 2007 May; 393(1-2):31-42. PubMed ID: 17350183
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alternative method for site-directed mutagenesis of complex polyketide synthase in Streptomyces albus JA3453.
    Song D; Coughlin J; Ju J; Zhou X; Shen B; Zhao C; Deng Z
    Acta Biochim Biophys Sin (Shanghai); 2008 Apr; 40(4):319-26. PubMed ID: 18401530
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification and characterization of the biosynthetic gene cluster of divergolides from Streptomyces sp. W112.
    Li SR; Zhao GS; Sun MW; He HG; Wang HX; Li YY; Lu CH; Shen YM
    Gene; 2014 Jul; 544(1):93-9. PubMed ID: 24768719
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insights into the pamamycin biosynthesis.
    Rebets Y; Brötz E; Manderscheid N; Tokovenko B; Myronovskyi M; Metz P; Petzke L; Luzhetskyy A
    Angew Chem Int Ed Engl; 2015 Feb; 54(7):2280-4. PubMed ID: 25537663
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Myxovirescin A biosynthesis is directed by hybrid polyketide synthases/nonribosomal peptide synthetase, 3-hydroxy-3-methylglutaryl-CoA synthases, and trans-acting acyltransferases.
    Simunovic V; Zapp J; Rachid S; Krug D; Meiser P; Müller R
    Chembiochem; 2006 Aug; 7(8):1206-20. PubMed ID: 16835859
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Type I polyketide synthases that require discrete acyltransferases.
    Cheng YQ; Coughlin JM; Lim SK; Shen B
    Methods Enzymol; 2009; 459():165-86. PubMed ID: 19362640
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel bioactive oxazolomycin isomers produced by Streptomyces albus JA3453.
    Kanzaki H; Wada K; Nitoda T; Kawazu K
    Biosci Biotechnol Biochem; 1998 Mar; 62(3):438-42. PubMed ID: 9571773
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.
    Li W; Ju J; Rajski SR; Osada H; Shen B
    J Biol Chem; 2008 Oct; 283(42):28607-17. PubMed ID: 18708355
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The methoxymalonyl-acyl carrier protein biosynthesis locus and the nearby gene with the beta-ketoacyl synthase domain are involved in the biosynthesis of galbonolides in Streptomyces galbus, but these loci are separate from the modular polyketide synthase gene cluster.
    Karki S; Kwon SY; Yoo HG; Suh JW; Park SH; Kwon HJ
    FEMS Microbiol Lett; 2010 Sep; 310(1):69-75. PubMed ID: 20662933
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Extender Unit Promiscuity and Orthogonal Protein Interactions of an Aminomalonyl-ACP Utilizing Trans-Acyltransferase from Zwittermicin Biosynthesis.
    Carpenter SM; Williams GJ
    ACS Chem Biol; 2018 Dec; 13(12):3361-3373. PubMed ID: 30484625
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase.
    Du L; Sánchez C; Chen M; Edwards DJ; Shen B
    Chem Biol; 2000 Aug; 7(8):623-42. PubMed ID: 11048953
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The AT₂ domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS.
    Musiol EM; Greule A; Härtner T; Kulik A; Wohlleben W; Weber T
    Chembiochem; 2013 Jul; 14(11):1343-52. PubMed ID: 23828654
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reconstitution of the FK228 biosynthetic pathway reveals cross talk between modular polyketide synthases and fatty acid synthase.
    Wesener SR; Potharla VY; Cheng YQ
    Appl Environ Microbiol; 2011 Feb; 77(4):1501-7. PubMed ID: 21183648
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biosynthetic pathway of peucemycin and identification of its derivative from Streptomyces peucetius.
    Magar RT; Pham VTT; Poudel PB; Nguyen HT; Bridget AF; Sohng JK
    Appl Microbiol Biotechnol; 2023 Feb; 107(4):1217-1231. PubMed ID: 36680588
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of phoslactomycin biosynthetic gene clusters from Streptomyces platensis SAM-0654 and characterization of PnR1 and PnR2 as positive transcriptional regulators.
    Chen YL; Zhao J; Liu W; Gao JF; Tao LM; Pan HX; Tang GL
    Gene; 2012 Nov; 509(2):195-200. PubMed ID: 22940146
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.