BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

291 related articles for article (PubMed ID: 20406983)

  • 1. ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.
    Marx C; Held JM; Gibson BW; Benz CC
    Cancer Res; 2010 May; 70(9):3709-17. PubMed ID: 20406983
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of an HSP90 modulated multi-step process for ERBB2 degradation in breast cancer cells.
    Castagnola P; Bellese G; Birocchi F; Gagliani MC; Tacchetti C; Cortese K
    Oncotarget; 2016 Dec; 7(51):85411-85429. PubMed ID: 27863425
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The HSP90 inhibitor geldanamycin perturbs endosomal structure and drives recycling ErbB2 and transferrin to modified MVBs/lysosomal compartments.
    Cortese K; Howes MT; Lundmark R; Tagliatti E; Bagnato P; Petrelli A; Bono M; McMahon HT; Parton RG; Tacchetti C
    Mol Biol Cell; 2013 Jan; 24(2):129-44. PubMed ID: 23154999
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cbl and Itch binding sites in ERBB4 CYT-1 and CYT-2 mediate K48- and K63-polyubiquitination, respectively.
    Meijer IM; van Rotterdam W; van Zoelen EJ; van Leeuwen JE
    Cell Signal; 2013 Feb; 25(2):470-8. PubMed ID: 23153581
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ubiquitination and proteasomal degradation of nucleophosmin-anaplastic lymphoma kinase induced by 17-allylamino-demethoxygeldanamycin: role of the co-chaperone carboxyl heat shock protein 70-interacting protein.
    Bonvini P; Dalla Rosa H; Vignes N; Rosolen A
    Cancer Res; 2004 May; 64(9):3256-64. PubMed ID: 15126367
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Clathrin-independent endocytosis of ErbB2 in geldanamycin-treated human breast cancer cells.
    Barr DJ; Ostermeyer-Fay AG; Matundan RA; Brown DA
    J Cell Sci; 2008 Oct; 121(Pt 19):3155-66. PubMed ID: 18765569
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Endoplasmic reticulum vacuolization and valosin-containing protein relocalization result from simultaneous hsp90 inhibition by geldanamycin and proteasome inhibition by velcade.
    Mimnaugh EG; Xu W; Vos M; Yuan X; Neckers L
    Mol Cancer Res; 2006 Sep; 4(9):667-81. PubMed ID: 16966435
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Geldanamycin stimulates internalization of ErbB2 in a proteasome-dependent way.
    Lerdrup M; Hommelgaard AM; Grandal M; van Deurs B
    J Cell Sci; 2006 Jan; 119(Pt 1):85-95. PubMed ID: 16352662
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity.
    Mimnaugh EG; Xu W; Vos M; Yuan X; Isaacs JS; Bisht KS; Gius D; Neckers L
    Mol Cancer Ther; 2004 May; 3(5):551-66. PubMed ID: 15141013
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protein kinase C mediated internalization of ErbB2 is independent of clathrin, ubiquitination and Hsp90 dissociation.
    Dietrich M; Malik MS; Nikolaysen F; Skeie M; Stang E
    Exp Cell Res; 2018 Oct; 371(1):139-150. PubMed ID: 30098331
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The deubiquitylase USP2 maintains ErbB2 abundance via counteracting endocytic degradation and represents a therapeutic target in ErbB2-positive breast cancer.
    Zhang J; Liu S; Li Q; Shi Y; Wu Y; Liu F; Wang S; Zaky MY; Yousuf W; Sun Q; Guo D; Wang T; Zhang Y; Wang Y; Li M; Liu H
    Cell Death Differ; 2020 Sep; 27(9):2710-2725. PubMed ID: 32327714
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Recycling of EGFR and ErbB2 is associated with impaired Hrs tyrosine phosphorylation and decreased deubiquitination by AMSH.
    Meijer IM; van Rotterdam W; van Zoelen EJ; van Leeuwen JE
    Cell Signal; 2012 Nov; 24(11):1981-8. PubMed ID: 22800866
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ErbB2 degradation mediated by the co-chaperone protein CHIP.
    Zhou P; Fernandes N; Dodge IL; Reddi AL; Rao N; Safran H; DiPetrillo TA; Wazer DE; Band V; Band H
    J Biol Chem; 2003 Apr; 278(16):13829-37. PubMed ID: 12574167
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells.
    Raja SM; Clubb RJ; Bhattacharyya M; Dimri M; Cheng H; Pan W; Ortega-Cava C; Lakku-Reddi A; Naramura M; Band V; Band H
    Cancer Biol Ther; 2008 Oct; 7(10):1630-40. PubMed ID: 18769124
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Geldanamycin-induced down-regulation of ErbB2 from the plasma membrane is clathrin dependent but proteasomal activity independent.
    Pedersen NM; Madshus IH; Haslekås C; Stang E
    Mol Cancer Res; 2008 Mar; 6(3):491-500. PubMed ID: 18337455
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Proteasome-regulated ERBB2 and estrogen receptor pathways in breast cancer.
    Marx C; Yau C; Banwait S; Zhou Y; Scott GK; Hann B; Park JW; Benz CC
    Mol Pharmacol; 2007 Jun; 71(6):1525-34. PubMed ID: 17392524
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chaperone-mediated 26S proteasome remodeling facilitates free K63 ubiquitin chain production and aggresome clearance.
    Nanduri P; Hao R; Fitzpatrick T; Yao TP
    J Biol Chem; 2015 Apr; 290(15):9455-64. PubMed ID: 25713068
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lysine 63-linked polyubiquitination is required for EGF receptor degradation.
    Huang F; Zeng X; Kim W; Balasubramani M; Fortian A; Gygi SP; Yates NA; Sorkin A
    Proc Natl Acad Sci U S A; 2013 Sep; 110(39):15722-7. PubMed ID: 24019463
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Formaldehyde Is a Potent Proteotoxic Stressor Causing Rapid Heat Shock Transcription Factor 1 Activation and Lys48-Linked Polyubiquitination of Proteins.
    Ortega-Atienza S; Rubis B; McCarthy C; Zhitkovich A
    Am J Pathol; 2016 Nov; 186(11):2857-2868. PubMed ID: 27639166
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The E3 ubiquitin ligase CHIP mediates ubiquitination and proteasomal degradation of PRMT5.
    Zhang HT; Zeng LF; He QY; Tao WA; Zha ZG; Hu CD
    Biochim Biophys Acta; 2016 Feb; 1863(2):335-46. PubMed ID: 26658161
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.