These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 20419112)

  • 21. An Evolutionarily Conserved Role of Presenilin in Neuronal Protection in the Aging
    Kang J; Shin S; Perrimon N; Shen J
    Genetics; 2017 Jul; 206(3):1479-1493. PubMed ID: 28495961
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The presenilin hypothesis of Alzheimer's disease: evidence for a loss-of-function pathogenic mechanism.
    Shen J; Kelleher RJ
    Proc Natl Acad Sci U S A; 2007 Jan; 104(2):403-9. PubMed ID: 17197420
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Mfn2 Ablation in the Adult Mouse Hippocampus and Cortex Causes Neuronal Death.
    Han S; Nandy P; Austria Q; Siedlak SL; Torres S; Fujioka H; Wang W; Zhu X
    Cells; 2020 Jan; 9(1):. PubMed ID: 31947766
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Presenilins are required for maintenance of neural stem cells in the developing brain.
    Kim WY; Shen J
    Mol Neurodegener; 2008 Jan; 3():2. PubMed ID: 18182109
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Hippocampal spatial memory impairments caused by the familial Alzheimer's disease-linked presenilin 1 M146V mutation.
    Sun X; Beglopoulos V; Mattson MP; Shen J
    Neurodegener Dis; 2005; 2(1):6-15. PubMed ID: 16908998
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Enhanced oxidative stress is an early event during development of Alzheimer-like pathologies in presenilin conditional knock-out mice.
    Gu F; Zhu M; Shi J; Hu Y; Zhao Z
    Neurosci Lett; 2008 Jul; 440(1):44-8. PubMed ID: 18539391
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Conditional forebrain inactivation of nicastrin causes progressive memory impairment and age-related neurodegeneration.
    Tabuchi K; Chen G; Südhof TC; Shen J
    J Neurosci; 2009 Jun; 29(22):7290-301. PubMed ID: 19494151
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Adult hippocampal neurogenesis occurs in the absence of Presenilin 1 and Presenilin 2.
    Dhaliwal J; Kannangara TS; Vaculik M; Xue Y; Kumar KL; Maione A; Béïque JC; Shen J; Lagace DC
    Sci Rep; 2018 Dec; 8(1):17931. PubMed ID: 30560948
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synaptic function of nicastrin in hippocampal neurons.
    Lee SH; Sharma M; Südhof TC; Shen J
    Proc Natl Acad Sci U S A; 2014 Jun; 111(24):8973-8. PubMed ID: 24889619
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Lipophorin receptors genetically modulate neurodegeneration caused by reduction of Psn expression in the aging Drosophila brain.
    Kang J; Zhang C; Wang Y; Peng J; Berger B; Perrimon N; Shen J
    Genetics; 2024 Jan; 226(1):. PubMed ID: 37996068
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Aberrant induction of Par-4 is involved in apoptosis of hippocampal neurons in presenilin-1 M146V mutant knock-in mice.
    Xie J; Chang X; Zhang X; Guo Q
    Brain Res; 2001 Oct; 915(1):1-10. PubMed ID: 11578614
    [TBL] [Abstract][Full Text] [Related]  

  • 32. ets-2 promotes the activation of a mitochondrial death pathway in Down's syndrome neurons.
    Helguera P; Pelsman A; Pigino G; Wolvetang E; Head E; Busciglio J
    J Neurosci; 2005 Mar; 25(9):2295-303. PubMed ID: 15745955
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis.
    Bursztajn S; DeSouza R; McPhie DL; Berman SA; Shioi J; Robakis NK; Neve RL
    J Neurosci; 1998 Dec; 18(23):9790-9. PubMed ID: 9822738
    [TBL] [Abstract][Full Text] [Related]  

  • 34. APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival.
    Lee SH; Kang J; Ho A; Watanabe H; Bolshakov VY; Shen J
    Neuron; 2020 Nov; 108(4):676-690.e8. PubMed ID: 32891188
    [TBL] [Abstract][Full Text] [Related]  

  • 35. CRTC1 Function During Memory Encoding Is Disrupted in Neurodegeneration.
    Parra-Damas A; Chen M; Enriquez-Barreto L; Ortega L; Acosta S; Perna JC; Fullana MN; Aguilera J; Rodríguez-Alvarez J; Saura CA
    Biol Psychiatry; 2017 Jan; 81(2):111-123. PubMed ID: 27587263
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Pik3c3 deletion in pyramidal neurons results in loss of synapses, extensive gliosis and progressive neurodegeneration.
    Wang L; Budolfson K; Wang F
    Neuroscience; 2011 Jan; 172():427-42. PubMed ID: 20955765
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Adult neurogenesis is functionally associated with AD-like neurodegeneration.
    Chen Q; Nakajima A; Choi SH; Xiong X; Sisodia SS; Tang YP
    Neurobiol Dis; 2008 Feb; 29(2):316-26. PubMed ID: 17980611
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Presenilin-1 mutations sensitize neurons to DNA damage-induced death by a mechanism involving perturbed calcium homeostasis and activation of calpains and caspase-12.
    Chan SL; Culmsee C; Haughey N; Klapper W; Mattson MP
    Neurobiol Dis; 2002 Oct; 11(1):2-19. PubMed ID: 12460542
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease.
    Xia D; Watanabe H; Wu B; Lee SH; Li Y; Tsvetkov E; Bolshakov VY; Shen J; Kelleher RJ
    Neuron; 2015 Mar; 85(5):967-81. PubMed ID: 25741723
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Increased oxidative stress and astrogliosis responses in conditional double-knockout mice of Alzheimer-like presenilin-1 and presenilin-2.
    Zhu M; Gu F; Shi J; Hu J; Hu Y; Zhao Z
    Free Radic Biol Med; 2008 Nov; 45(10):1493-9. PubMed ID: 18822370
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.