These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 20421934)

  • 1. Deletion of the WD40 domain of LRRK2 in Zebrafish causes Parkinsonism-like loss of neurons and locomotive defect.
    Sheng D; Qu D; Kwok KH; Ng SS; Lim AY; Aw SS; Lee CW; Sung WK; Tan EK; Lufkin T; Jesuthasan S; Sinnakaruppan M; Liu J
    PLoS Genet; 2010 Apr; 6(4):e1000914. PubMed ID: 20421934
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disruption of LRRK2 does not cause specific loss of dopaminergic neurons in zebrafish.
    Ren G; Xin S; Li S; Zhong H; Lin S
    PLoS One; 2011; 6(6):e20630. PubMed ID: 21698186
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LRRK2 knockdown in zebrafish causes developmental defects, neuronal loss, and synuclein aggregation.
    Prabhudesai S; Bensabeur FZ; Abdullah R; Basak I; Baez S; Alves G; Holtzman NG; Larsen JP; Møller SG
    J Neurosci Res; 2016 Aug; 94(8):717-35. PubMed ID: 27265751
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Drosophila model for LRRK2-linked parkinsonism.
    Liu Z; Wang X; Yu Y; Li X; Wang T; Jiang H; Ren Q; Jiao Y; Sawa A; Moran T; Ross CA; Montell C; Smith WW
    Proc Natl Acad Sci U S A; 2008 Feb; 105(7):2693-8. PubMed ID: 18258746
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Homozygous mutation of the LRRK2 ROC domain as a novel genetic model of parkinsonism.
    Chen ML; Wu RM
    J Biomed Sci; 2022 Aug; 29(1):60. PubMed ID: 35965315
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lovastatin protects neurite degeneration in LRRK2-G2019S parkinsonism through activating the Akt/Nrf pathway and inhibiting GSK3β activity.
    Lin CH; Lin HI; Chen ML; Lai TT; Cao LP; Farrer MJ; Wu RM; Chien CT
    Hum Mol Genet; 2016 May; 25(10):1965-1978. PubMed ID: 26931464
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The familial Parkinsonism gene LRRK2 regulates neurite process morphology.
    MacLeod D; Dowman J; Hammond R; Leete T; Inoue K; Abeliovich A
    Neuron; 2006 Nov; 52(4):587-93. PubMed ID: 17114044
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A dual inhibitor targeting HMG-CoA reductase and histone deacetylase mitigates neurite degeneration in
    Lin CH; Lin HY; Fang JM; Chen CC
    Aging (Albany NY); 2020 Nov; 12(24):25581-25598. PubMed ID: 33231564
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Loss of LRRK2/PARK8 induces degeneration of dopaminergic neurons in Drosophila.
    Lee SB; Kim W; Lee S; Chung J
    Biochem Biophys Res Commun; 2007 Jun; 358(2):534-9. PubMed ID: 17498648
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Drosophila hep pathway mediates Lrrk2-induced neurodegeneration.
    Yang D; Thomas JM; Li T; Lee Y; Liu Z; Smith WW
    Biochem Cell Biol; 2018 Aug; 96(4):441-449. PubMed ID: 29268033
    [TBL] [Abstract][Full Text] [Related]  

  • 11. LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease.
    Yao C; El Khoury R; Wang W; Byrd TA; Pehek EA; Thacker C; Zhu X; Smith MA; Wilson-Delfosse AL; Chen SG
    Neurobiol Dis; 2010 Oct; 40(1):73-81. PubMed ID: 20382224
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dopaminergic neuronal loss and dopamine-dependent locomotor defects in Fbxo7-deficient zebrafish.
    Zhao T; Zondervan-van der Linde H; Severijnen LA; Oostra BA; Willemsen R; Bonifati V
    PLoS One; 2012; 7(11):e48911. PubMed ID: 23133663
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lrrk2 modulation of Wnt signaling during zebrafish development.
    Wint JM; Sirotkin HI
    J Neurosci Res; 2020 Oct; 98(10):1831-1842. PubMed ID: 32623786
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Deletion of lrrk2 causes early developmental abnormalities and age-dependent increase of monoamine catabolism in the zebrafish brain.
    Suzzi S; Ahrendt R; Hans S; Semenova SA; Chekuru A; Wirsching P; Kroehne V; Bilican S; Sayed S; Winkler S; Spieß S; Machate A; Kaslin J; Panula P; Brand M
    PLoS Genet; 2021 Sep; 17(9):e1009794. PubMed ID: 34516550
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional and Morphological Correlates in the Drosophila LRRK2 loss-of-function Model of Parkinson's Disease: Drug Effects of Withania somnifera (Dunal) Administration.
    De Rose F; Marotta R; Poddighe S; Talani G; Catelani T; Setzu MD; Solla P; Marrosu F; Sanna E; Kasture S; Acquas E; Liscia A
    PLoS One; 2016; 11(1):e0146140. PubMed ID: 26727265
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Localization of Parkinson's disease-associated LRRK2 in normal and pathological human brain.
    Higashi S; Biskup S; West AB; Trinkaus D; Dawson VL; Faull RL; Waldvogel HJ; Arai H; Dawson TM; Moore DJ; Emson PC
    Brain Res; 2007 Jun; 1155():208-19. PubMed ID: 17512502
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Novel LRRK2 Variant p.G2294R in the WD40 Domain Identified in Familial Parkinson's Disease Affects LRRK2 Protein Levels.
    Ogata J; Hirao K; Nishioka K; Hayashida A; Li Y; Yoshino H; Shimizu S; Hattori N; Imai Y
    Int J Mol Sci; 2021 Apr; 22(7):. PubMed ID: 33918221
    [No Abstract]   [Full Text] [Related]  

  • 18. The role of the LRRK2 gene in Parkinsonism.
    Li JQ; Tan L; Yu JT
    Mol Neurodegener; 2014 Nov; 9():47. PubMed ID: 25391693
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Up-regulation of autophagy-related gene 5 (
    Hu ZY; Chen B; Zhang JP; Ma YY
    J Biol Chem; 2017 Nov; 292(44):18062-18074. PubMed ID: 28928221
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein.
    Niu J; Yu M; Wang C; Xu Z
    J Neurochem; 2012 Aug; 122(3):650-8. PubMed ID: 22639965
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.