BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

376 related articles for article (PubMed ID: 20424113)

  • 1. Disulfiram treatment facilitates phosphoinositide 3-kinase inhibition in human breast cancer cells in vitro and in vivo.
    Zhang H; Chen D; Ringler J; Chen W; Cui QC; Ethier SP; Dou QP; Wu G
    Cancer Res; 2010 May; 70(10):3996-4004. PubMed ID: 20424113
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biomarkers of response to Akt inhibitor MK-2206 in breast cancer.
    Sangai T; Akcakanat A; Chen H; Tarco E; Wu Y; Do KA; Miller TW; Arteaga CL; Mills GB; Gonzalez-Angulo AM; Meric-Bernstam F
    Clin Cancer Res; 2012 Oct; 18(20):5816-28. PubMed ID: 22932669
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Simultaneous inhibition of EGFR and PI3K enhances radiosensitivity in human breast cancer.
    Li P; Zhang Q; Torossian A; Li ZB; Xu WC; Lu B; Fu S
    Int J Radiat Oncol Biol Phys; 2012 Jul; 83(3):e391-7. PubMed ID: 22414288
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting the PI3K/Akt/mTOR pathway with the pan-Akt inhibitor GDC-0068 in PIK3CA-mutant breast cancer brain metastases.
    Ippen FM; Grosch JK; Subramanian M; Kuter BM; Liederer BM; Plise EG; Mora JL; Nayyar N; Schmidt SP; Giobbie-Hurder A; Martinez-Lage M; Carter SL; Cahill DP; Wakimoto H; Brastianos PK
    Neuro Oncol; 2019 Nov; 21(11):1401-1411. PubMed ID: 31173106
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Response of non-small cell lung cancer cells to the inhibitors of phosphatidylinositol 3-kinase/Akt- and MAPK kinase 4/c-Jun NH2-terminal kinase pathways: an effective therapeutic strategy for lung cancer.
    Lee HY; Oh SH; Suh YA; Baek JH; Papadimitrakopoulou V; Huang S; Hong WK
    Clin Cancer Res; 2005 Aug; 11(16):6065-74. PubMed ID: 16115952
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PTEN activation sensitizes breast cancer to PI3-kinase inhibitor through the β-catenin signaling pathway.
    Ren Y; Zhou X; Qi Y; Li G; Mei M; Yao Z
    Oncol Rep; 2012 Sep; 28(3):943-8. PubMed ID: 22710837
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Disulfiram targets cancer stem-like properties and the HER2/Akt signaling pathway in HER2-positive breast cancer.
    Kim JY; Cho Y; Oh E; Lee N; An H; Sung D; Cho TM; Seo JH
    Cancer Lett; 2016 Aug; 379(1):39-48. PubMed ID: 27238567
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer.
    She QB; Gruvberger-Saal SK; Maurer M; Chen Y; Jumppanen M; Su T; Dendy M; Lau YK; Memeo L; Horlings HM; van de Vijver MJ; Isola J; Hibshoosh H; Rosen N; Parsons R; Saal LH
    BMC Cancer; 2016 Aug; 16():587. PubMed ID: 27484095
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combinatorial therapy with adenoviral-mediated PTEN and a PI3K inhibitor suppresses malignant glioma cell growth in vitro and in vivo by regulating the PI3K/AKT signaling pathway.
    Nan Y; Guo L; Song Y; Wang L; Yu K; Huang Q; Zhong Y
    J Cancer Res Clin Oncol; 2017 Aug; 143(8):1477-1487. PubMed ID: 28401302
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disulfiram/Cu Kills and Sensitizes
    Xie J; Liu J; Zhao M; Li X; Wang Y; Zhao Y; Cao H; Ji M; Chen M; Hou P
    Int J Mol Sci; 2023 Feb; 24(4):. PubMed ID: 36834830
    [No Abstract]   [Full Text] [Related]  

  • 11. Disulfiram/copper shows potent cytotoxic effects on myelodysplastic syndromes via inducing Bip-mediated apoptosis and suppressing autophagy.
    Zha J; Bi S; Deng M; Chen K; Shi P; Feng L; He J; Pu X; Guo C; Zhao H; Li Z; Jiang Y; Song H; Xu B
    Eur J Pharmacol; 2021 Jul; 902():174107. PubMed ID: 33865831
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dietary restriction-resistant human tumors harboring the PIK3CA-activating mutation H1047R are sensitive to metformin.
    Cufí S; Corominas-Faja B; Lopez-Bonet E; Bonavia R; Pernas S; López IÁ; Dorca J; Martínez S; López NB; Fernández SD; Cuyàs E; Visa J; Rodríguez-Gallego E; Quirantes-Piné R; Segura-Carretero A; Joven J; Martin-Castillo B; Menendez JA
    Oncotarget; 2013 Sep; 4(9):1484-95. PubMed ID: 23986086
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combination of the 6-thioguanine and disulfiram/Cu synergistically inhibits proliferation of triple-negative breast cancer cells by enhancing DNA damage and disrupting DNA damage checkpoint.
    Chu M; An X; Zhang D; Li Q; Dai X; Yu H; Li Z
    Biochim Biophys Acta Mol Cell Res; 2022 Feb; 1869(2):119169. PubMed ID: 34763028
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The disulfiram/copper complex induces apoptosis and inhibits tumour growth in human osteosarcoma by activating the ROS/JNK signalling pathway.
    Guo W; Zhang X; Lin L; Wang H; He E; Wang G; Zhao Q
    J Biochem; 2021 Oct; 170(2):275-287. PubMed ID: 33792698
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Association between gain-of-function mutations in PIK3CA and resistance to HER2-targeted agents in HER2-amplified breast cancer cell lines.
    Kataoka Y; Mukohara T; Shimada H; Saijo N; Hirai M; Minami H
    Ann Oncol; 2010 Feb; 21(2):255-262. PubMed ID: 19633047
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 1,25-dihydroxyvitamin D(3) and PI3K/AKT inhibitors synergistically inhibit growth and induce senescence in prostate cancer cells.
    Axanova LS; Chen YQ; McCoy T; Sui G; Cramer SD
    Prostate; 2010 Nov; 70(15):1658-71. PubMed ID: 20583132
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dual inhibition of PI3K and mTOR mitigates compensatory AKT activation and improves tamoxifen response in breast cancer.
    Chen X; Zhao M; Hao M; Sun X; Wang J; Mao Y; Zu L; Liu J; Shen Y; Wang J; Shen K
    Mol Cancer Res; 2013 Oct; 11(10):1269-78. PubMed ID: 23814023
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PI3K/PTEN/AKT signaling regulates prostate tumor angiogenesis.
    Fang J; Ding M; Yang L; Liu LZ; Jiang BH
    Cell Signal; 2007 Dec; 19(12):2487-97. PubMed ID: 17826033
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway.
    DeGraffenried LA; Fulcher L; Friedrichs WE; Grünwald V; Ray RB; Hidalgo M
    Ann Oncol; 2004 Oct; 15(10):1510-6. PubMed ID: 15367412
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Disulfiram/copper induces antitumor activity against gastric cancer cells in vitro and in vivo by inhibiting S6K1 and c-Myc.
    Du C; Guan X; Liu Y; Xu Z; Du X; Li B; Wang M; Zheng Z
    Cancer Chemother Pharmacol; 2022 Apr; 89(4):451-458. PubMed ID: 35201421
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.