These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

343 related articles for article (PubMed ID: 20442453)

  • 1. Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling".
    Pavlides S; Tsirigos A; Vera I; Flomenberg N; Frank PG; Casimiro MC; Wang C; Pestell RG; Martinez-Outschoorn UE; Howell A; Sotgia F; Lisanti MP
    Aging (Albany NY); 2010 Apr; 2(4):185-99. PubMed ID: 20442453
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": a transcriptional informatics analysis with validation.
    Pavlides S; Tsirigos A; Vera I; Flomenberg N; Frank PG; Casimiro MC; Wang C; Fortina P; Addya S; Pestell RG; Martinez-Outschoorn UE; Sotgia F; Lisanti MP
    Cell Cycle; 2010 Jun; 9(11):2201-19. PubMed ID: 20519932
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma.
    Pavlides S; Whitaker-Menezes D; Castello-Cros R; Flomenberg N; Witkiewicz AK; Frank PG; Casimiro MC; Wang C; Fortina P; Addya S; Pestell RG; Martinez-Outschoorn UE; Sotgia F; Lisanti MP
    Cell Cycle; 2009 Dec; 8(23):3984-4001. PubMed ID: 19923890
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular profiling of a lethal tumor microenvironment, as defined by stromal caveolin-1 status in breast cancers.
    Witkiewicz AK; Kline J; Queenan M; Brody JR; Tsirigos A; Bilal E; Pavlides S; Ertel A; Sotgia F; Lisanti MP
    Cell Cycle; 2011 Jun; 10(11):1794-809. PubMed ID: 21521946
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: evidence for stromal-epithelial metabolic coupling.
    Migneco G; Whitaker-Menezes D; Chiavarina B; Castello-Cros R; Pavlides S; Pestell RG; Fatatis A; Flomenberg N; Tsirigos A; Howell A; Martinez-Outschoorn UE; Sotgia F; Lisanti MP
    Cell Cycle; 2010 Jun; 9(12):2412-22. PubMed ID: 20562527
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism.
    Pavlides S; Tsirigos A; Migneco G; Whitaker-Menezes D; Chiavarina B; Flomenberg N; Frank PG; Casimiro MC; Wang C; Pestell RG; Martinez-Outschoorn UE; Howell A; Sotgia F; Lisanti MP
    Cell Cycle; 2010 Sep; 9(17):3485-505. PubMed ID: 20861672
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells.
    Martinez-Outschoorn UE; Balliet RM; Rivadeneira DB; Chiavarina B; Pavlides S; Wang C; Whitaker-Menezes D; Daumer KM; Lin Z; Witkiewicz AK; Flomenberg N; Howell A; Pestell RG; Knudsen ES; Sotgia F; Lisanti MP
    Cell Cycle; 2010 Aug; 9(16):3256-76. PubMed ID: 20814239
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Using the "reverse Warburg effect" to identify high-risk breast cancer patients: stromal MCT4 predicts poor clinical outcome in triple-negative breast cancers.
    Witkiewicz AK; Whitaker-Menezes D; Dasgupta A; Philp NJ; Lin Z; Gandara R; Sneddon S; Martinez-Outschoorn UE; Sotgia F; Lisanti MP
    Cell Cycle; 2012 Mar; 11(6):1108-17. PubMed ID: 22313602
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment.
    Martinez-Outschoorn UE; Trimmer C; Lin Z; Whitaker-Menezes D; Chiavarina B; Zhou J; Wang C; Pavlides S; Martinez-Cantarin MP; Capozza F; Witkiewicz AK; Flomenberg N; Howell A; Pestell RG; Caro J; Lisanti MP; Sotgia F
    Cell Cycle; 2010 Sep; 9(17):3515-33. PubMed ID: 20855962
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production.
    Guido C; Whitaker-Menezes D; Capparelli C; Balliet R; Lin Z; Pestell RG; Howell A; Aquila S; Andò S; Martinez-Outschoorn U; Sotgia F; Lisanti MP
    Cell Cycle; 2012 Aug; 11(16):3019-35. PubMed ID: 22874531
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function.
    Martinez-Outschoorn U; Sotgia F; Lisanti MP
    Semin Oncol; 2014 Apr; 41(2):195-216. PubMed ID: 24787293
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The reverse Warburg effect: glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts.
    Bonuccelli G; Whitaker-Menezes D; Castello-Cros R; Pavlides S; Pestell RG; Fatatis A; Witkiewicz AK; Vander Heiden MG; Migneco G; Chiavarina B; Frank PG; Capozza F; Flomenberg N; Martinez-Outschoorn UE; Sotgia F; Lisanti MP
    Cell Cycle; 2010 May; 9(10):1960-71. PubMed ID: 20495363
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.
    Chiavarina B; Whitaker-Menezes D; Martinez-Outschoorn UE; Witkiewicz AK; Birbe R; Howell A; Pestell RG; Smith J; Daniel R; Sotgia F; Lisanti MP
    Cancer Biol Ther; 2011 Dec; 12(12):1101-13. PubMed ID: 22236875
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts.
    Trimmer C; Sotgia F; Whitaker-Menezes D; Balliet RM; Eaton G; Martinez-Outschoorn UE; Pavlides S; Howell A; Iozzo RV; Pestell RG; Scherer PE; Capozza F; Lisanti MP
    Cancer Biol Ther; 2011 Feb; 11(4):383-94. PubMed ID: 21150282
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue.
    Sotgia F; Whitaker-Menezes D; Martinez-Outschoorn UE; Flomenberg N; Birbe RC; Witkiewicz AK; Howell A; Philp NJ; Pestell RG; Lisanti MP
    Cell Cycle; 2012 Apr; 11(7):1445-54. PubMed ID: 22395432
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment.
    Sotgia F; Martinez-Outschoorn UE; Pavlides S; Howell A; Pestell RG; Lisanti MP
    Breast Cancer Res; 2011 Jul; 13(4):213. PubMed ID: 21867571
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: understanding the aging and cancer connection.
    Balliet RM; Capparelli C; Guido C; Pestell TG; Martinez-Outschoorn UE; Lin Z; Whitaker-Menezes D; Chiavarina B; Pestell RG; Howell A; Sotgia F; Lisanti MP
    Cell Cycle; 2011 Dec; 10(23):4065-73. PubMed ID: 22129993
    [TBL] [Abstract][Full Text] [Related]  

  • 18. BRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: implications for breast cancer prevention with antioxidant therapies.
    Martinez-Outschoorn UE; Balliet R; Lin Z; Whitaker-Menezes D; Birbe RC; Bombonati A; Pavlides S; Lamb R; Sneddon S; Howell A; Sotgia F; Lisanti MP
    Cell Cycle; 2012 Dec; 11(23):4402-13. PubMed ID: 23172369
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolic phenotypes in triple-negative breast cancer.
    Kim S; Kim DH; Jung WH; Koo JS
    Tumour Biol; 2013 Jun; 34(3):1699-712. PubMed ID: 23443971
    [TBL] [Abstract][Full Text] [Related]  

  • 20. JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: connecting fibrosis, inflammation, and stemness for cancer prevention.
    Lisanti MP; Tsirigos A; Pavlides S; Reeves KJ; Peiris-Pagès M; Chadwick AL; Sanchez-Alvarez R; Lamb R; Howell A; Martinez-Outschoorn UE; Sotgia F
    Cell Cycle; 2014; 13(4):580-99. PubMed ID: 24434780
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.