These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 20444979)

  • 1. Fusel alcohols regulate translation initiation by inhibiting eIF2B to reduce ternary complex in a mechanism that may involve altering the integrity and dynamics of the eIF2B body.
    Taylor EJ; Campbell SG; Griffiths CD; Reid PJ; Slaven JW; Harrison RJ; Sims PF; Pavitt GD; Delneri D; Ashe MP
    Mol Biol Cell; 2010 Jul; 21(13):2202-16. PubMed ID: 20444979
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The beta/Gcd7 subunit of eukaryotic translation initiation factor 2B (eIF2B), a guanine nucleotide exchange factor, is crucial for binding eIF2 in vivo.
    Dev K; Qiu H; Dong J; Zhang F; Barthlme D; Hinnebusch AG
    Mol Cell Biol; 2010 Nov; 30(21):5218-33. PubMed ID: 20805354
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation.
    Gomez E; Pavitt GD
    Mol Cell Biol; 2000 Jun; 20(11):3965-76. PubMed ID: 10805739
    [TBL] [Abstract][Full Text] [Related]  

  • 4. eIF2B promotes eIF5 dissociation from eIF2*GDP to facilitate guanine nucleotide exchange for translation initiation.
    Jennings MD; Zhou Y; Mohammad-Qureshi SS; Bennett D; Pavitt GD
    Genes Dev; 2013 Dec; 27(24):2696-707. PubMed ID: 24352424
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation.
    Krishnamoorthy T; Pavitt GD; Zhang F; Dever TE; Hinnebusch AG
    Mol Cell Biol; 2001 Aug; 21(15):5018-30. PubMed ID: 11438658
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of eukaryotic translation initiation factor 2B.
    Kashiwagi K; Takahashi M; Nishimoto M; Hiyama TB; Higo T; Umehara T; Sakamoto K; Ito T; Yokoyama S
    Nature; 2016 Mar; 531(7592):122-5. PubMed ID: 26901872
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel eIF2B-dependent mechanism of translational control in yeast as a response to fusel alcohols.
    Ashe MP; Slaven JW; De Long SK; Ibrahimo S; Sachs AB
    EMBO J; 2001 Nov; 20(22):6464-74. PubMed ID: 11707417
    [TBL] [Abstract][Full Text] [Related]  

  • 8. eIF2B is a decameric guanine nucleotide exchange factor with a γ2ε2 tetrameric core.
    Gordiyenko Y; Schmidt C; Jennings MD; Matak-Vinkovic D; Pavitt GD; Robinson CV
    Nat Commun; 2014 May; 5():3902. PubMed ID: 24852487
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dynamic cycling of eIF2 through a large eIF2B-containing cytoplasmic body: implications for translation control.
    Campbell SG; Hoyle NP; Ashe MP
    J Cell Biol; 2005 Sep; 170(6):925-34. PubMed ID: 16157703
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biochemical analysis of the eIF2beta gamma complex reveals a structural function for eIF2alpha in catalyzed nucleotide exchange.
    Nika J; Rippel S; Hannig EM
    J Biol Chem; 2001 Jan; 276(2):1051-6. PubMed ID: 11042214
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation.
    Singh CR; Lee B; Udagawa T; Mohammad-Qureshi SS; Yamamoto Y; Pavitt GD; Asano K
    EMBO J; 2006 Oct; 25(19):4537-46. PubMed ID: 16990799
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2.
    Yang W; Hinnebusch AG
    Mol Cell Biol; 1996 Nov; 16(11):6603-16. PubMed ID: 8887689
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Localization of the translational guanine nucleotide exchange factor eIF2B: a common theme for GEFs?
    Campbell SG; Ashe MP
    Cell Cycle; 2006 Apr; 5(7):678-80. PubMed ID: 16582624
    [TBL] [Abstract][Full Text] [Related]  

  • 14. eIF2β is critical for eIF5-mediated GDP-dissociation inhibitor activity and translational control.
    Jennings MD; Kershaw CJ; White C; Hoyle D; Richardson JP; Costello JL; Donaldson IJ; Zhou Y; Pavitt GD
    Nucleic Acids Res; 2016 Nov; 44(20):9698-9709. PubMed ID: 27458202
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural basis for the inhibition of translation through eIF2α phosphorylation.
    Gordiyenko Y; Llácer JL; Ramakrishnan V
    Nat Commun; 2019 Jun; 10(1):2640. PubMed ID: 31201334
    [TBL] [Abstract][Full Text] [Related]  

  • 16. eIF2B Mechanisms of Action and Regulation: A Thermodynamic View.
    Bogorad AM; Lin KY; Marintchev A
    Biochemistry; 2018 Mar; 57(9):1426-1435. PubMed ID: 29425030
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The alpha subunit of eukaryotic initiation factor 2B (eIF2B) is required for eIF2-mediated translational suppression of vesicular stomatitis virus.
    Elsby R; Heiber JF; Reid P; Kimball SR; Pavitt GD; Barber GN
    J Virol; 2011 Oct; 85(19):9716-25. PubMed ID: 21795329
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Clues to the mechanism of action of eIF2B, the guanine-nucleotide-exchange factor for translation initiation.
    Mohammad-Qureshi SS; Jennings MD; Pavitt GD
    Biochem Soc Trans; 2008 Aug; 36(Pt 4):658-64. PubMed ID: 18631136
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel mechanisms of eIF2B action and regulation by eIF2α phosphorylation.
    Bogorad AM; Lin KY; Marintchev A
    Nucleic Acids Res; 2017 Nov; 45(20):11962-11979. PubMed ID: 29036434
    [TBL] [Abstract][Full Text] [Related]  

  • 20. eIF2B: recent structural and functional insights into a key regulator of translation.
    Wortham NC; Proud CG
    Biochem Soc Trans; 2015 Dec; 43(6):1234-40. PubMed ID: 26614666
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.