These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 20445930)

  • 1. Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation.
    Lowther J; Yard BA; Johnson KA; Carter LG; Bhat VT; Raman MC; Clarke DJ; Ramakers B; McMahon SA; Naismith JH; Campopiano DJ
    Mol Biosyst; 2010 Sep; 6(9):1682-93. PubMed ID: 20445930
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of a conserved arginine residue during catalysis in serine palmitoyltransferase.
    Lowther J; Charmier G; Raman MC; Ikushiro H; Hayashi H; Campopiano DJ
    FEBS Lett; 2011 Jun; 585(12):1729-34. PubMed ID: 21514297
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reactions of serine palmitoyltransferase with serine and molecular mechanisms of the actions of serine derivatives as inhibitors.
    Ikushiro H; Hayashi H; Kagamiyama H
    Biochemistry; 2004 Feb; 43(4):1082-92. PubMed ID: 14744154
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular characterization of membrane-associated soluble serine palmitoyltransferases from Sphingobacterium multivorum and Bdellovibrio stolpii.
    Ikushiro H; Islam MM; Tojo H; Hayashi H
    J Bacteriol; 2007 Aug; 189(15):5749-61. PubMed ID: 17557831
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The external aldimine form of serine palmitoyltransferase: structural, kinetic, and spectroscopic analysis of the wild-type enzyme and HSAN1 mutant mimics.
    Raman MCC; Johnson KA; Yard BA; Lowther J; Carter LG; Naismith JH; Campopiano DJ
    J Biol Chem; 2009 Jun; 284(25):17328-17339. PubMed ID: 19376777
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural, mechanistic and regulatory studies of serine palmitoyltransferase.
    Lowther J; Naismith JH; Dunn TM; Campopiano DJ
    Biochem Soc Trans; 2012 Jun; 40(3):547-54. PubMed ID: 22616865
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanism of D-Cycloserine Inhibition of D-Amino Acid Transaminase from Haliscomenobacter hydrossis.
    Bakunova AK; Matyuta IO; Nikolaeva AY; Boyko KM; Popov VO; Bezsudnova EY
    Biochemistry (Mosc); 2023 May; 88(5):687-697. PubMed ID: 37331714
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The pyridoxal 5'-phosphate (PLP)-dependent enzyme serine palmitoyltransferase (SPT): effects of the small subunits and insights from bacterial mimics of human hLCB2a HSAN1 mutations.
    Beattie AE; Gupta SD; Frankova L; Kazlauskaite A; Harmon JM; Dunn TM; Campopiano DJ
    Biomed Res Int; 2013; 2013():194371. PubMed ID: 24175284
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
    Nakamura R; Ogawa S; Takahashi Y; Fujishiro T
    FEBS J; 2022 Oct; 289(19):5947-5970. PubMed ID: 35395703
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Racemization of the substrate and product by serine palmitoyltransferase from Sphingobacterium multivorum yields two enantiomers of the product from d-serine.
    Ikushiro H; Honda T; Murai Y; Murakami T; Takahashi A; Sawai T; Goto H; Ikushiro SI; Miyahara I; Hirabayashi Y; Kamiya N; Monde K; Yano T
    J Biol Chem; 2024 Mar; 300(3):105728. PubMed ID: 38325740
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The chemical basis of serine palmitoyltransferase inhibition by myriocin.
    Wadsworth JM; Clarke DJ; McMahon SA; Lowther JP; Beattie AE; Langridge-Smith PR; Broughton HB; Dunn TM; Naismith JH; Campopiano DJ
    J Am Chem Soc; 2013 Sep; 135(38):14276-85. PubMed ID: 23957439
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reconstitution of the pyridoxal 5'-phosphate (PLP) dependent enzyme serine palmitoyltransferase (SPT) with pyridoxal reveals a crucial role for the phosphate during catalysis.
    Beattie AE; Clarke DJ; Wadsworth JM; Lowther J; Sin HL; Campopiano DJ
    Chem Commun (Camb); 2013 Aug; 49(63):7058-60. PubMed ID: 23814788
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The structure of serine palmitoyltransferase; gateway to sphingolipid biosynthesis.
    Yard BA; Carter LG; Johnson KA; Overton IM; Dorward M; Liu H; McMahon SA; Oke M; Puech D; Barton GJ; Naismith JH; Campopiano DJ
    J Mol Biol; 2007 Jul; 370(5):870-86. PubMed ID: 17559874
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Acceleration of the substrate Calpha deprotonation by an analogue of the second substrate palmitoyl-CoA in Serine Palmitoyltransferase.
    Ikushiro H; Fujii S; Shiraiwa Y; Hayashi H
    J Biol Chem; 2008 Mar; 283(12):7542-53. PubMed ID: 18167344
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanism-Based Inhibition of the Mycobacterium tuberculosis Branched-Chain Aminotransferase by d- and l-Cycloserine.
    Amorim Franco TM; Favrot L; Vergnolle O; Blanchard JS
    ACS Chem Biol; 2017 May; 12(5):1235-1244. PubMed ID: 28272868
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multifunctional role of His159in the catalytic reaction of serine palmitoyltransferase.
    Shiraiwa Y; Ikushiro H; Hayashi H
    J Biol Chem; 2009 Jun; 284(23):15487-95. PubMed ID: 19346561
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural insights into the enzymatic mechanism of serine palmitoyltransferase from Sphingobacterium multivorum.
    Ikushiro H; Islam MM; Okamoto A; Hoseki J; Murakawa T; Fujii S; Miyahara I; Hayashi H
    J Biochem; 2009 Oct; 146(4):549-62. PubMed ID: 19564159
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bacterial serine palmitoyltransferase: a water-soluble homodimeric prototype of the eukaryotic enzyme.
    Ikushiro H; Hayashi H; Kagamiyama H
    Biochim Biophys Acta; 2003 Apr; 1647(1-2):116-20. PubMed ID: 12686119
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A side reaction of alanine racemase: transamination of cycloserine.
    Fenn TD; Stamper GF; Morollo AA; Ringe D
    Biochemistry; 2003 May; 42(19):5775-83. PubMed ID: 12741835
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A water-soluble homodimeric serine palmitoyltransferase from Sphingomonas paucimobilis EY2395T strain. Purification, characterization, cloning, and overproduction.
    Ikushiro H; Hayashi H; Kagamiyama H
    J Biol Chem; 2001 May; 276(21):18249-56. PubMed ID: 11279212
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.