386 related articles for article (PubMed ID: 20447471)
1. S-nitrosylation of Drp1 links excessive mitochondrial fission to neuronal injury in neurodegeneration.
Nakamura T; Cieplak P; Cho DH; Godzik A; Lipton SA
Mitochondrion; 2010 Aug; 10(5):573-8. PubMed ID: 20447471
[TBL] [Abstract][Full Text] [Related]
2. S-nitrosylation of dynamin-related protein 1 mediates mutant huntingtin-induced mitochondrial fragmentation and neuronal injury in Huntington's disease.
Haun F; Nakamura T; Shiu AD; Cho DH; Tsunemi T; Holland EA; La Spada AR; Lipton SA
Antioxid Redox Signal; 2013 Oct; 19(11):1173-84. PubMed ID: 23641925
[TBL] [Abstract][Full Text] [Related]
3. S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury.
Cho DH; Nakamura T; Fang J; Cieplak P; Godzik A; Gu Z; Lipton SA
Science; 2009 Apr; 324(5923):102-5. PubMed ID: 19342591
[TBL] [Abstract][Full Text] [Related]
4. Nitric oxide links mitochondrial fission to Alzheimer's disease.
Westermann B
Sci Signal; 2009 May; 2(69):pe29. PubMed ID: 19417214
[TBL] [Abstract][Full Text] [Related]
5. S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease.
Bossy B; Petrilli A; Klinglmayr E; Chen J; Lütz-Meindl U; Knott AB; Masliah E; Schwarzenbacher R; Bossy-Wetzel E
J Alzheimers Dis; 2010; 20 Suppl 2(Suppl 2):S513-26. PubMed ID: 20463395
[TBL] [Abstract][Full Text] [Related]
6. Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
Manczak M; Reddy PH
Hum Mol Genet; 2012 Jun; 21(11):2538-47. PubMed ID: 22367970
[TBL] [Abstract][Full Text] [Related]
7. Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.
Manczak M; Calkins MJ; Reddy PH
Hum Mol Genet; 2011 Jul; 20(13):2495-509. PubMed ID: 21459773
[TBL] [Abstract][Full Text] [Related]
8. Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases.
Reddy PH; Reddy TP; Manczak M; Calkins MJ; Shirendeb U; Mao P
Brain Res Rev; 2011 Jun; 67(1-2):103-18. PubMed ID: 21145355
[TBL] [Abstract][Full Text] [Related]
9. Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.
Wang X; Su B; Lee HG; Li X; Perry G; Smith MA; Zhu X
J Neurosci; 2009 Jul; 29(28):9090-103. PubMed ID: 19605646
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell.
Gan X; Huang S; Wu L; Wang Y; Hu G; Li G; Zhang H; Yu H; Swerdlow RH; Chen JX; Yan SS
Biochim Biophys Acta; 2014 Feb; 1842(2):220-31. PubMed ID: 24252614
[TBL] [Abstract][Full Text] [Related]
11. Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis.
Kim DI; Lee KH; Gabr AA; Choi GE; Kim JS; Ko SH; Han HJ
Biochim Biophys Acta; 2016 Nov; 1863(11):2820-2834. PubMed ID: 27599716
[TBL] [Abstract][Full Text] [Related]
12. Redox regulation of mitochondrial fission, protein misfolding, synaptic damage, and neuronal cell death: potential implications for Alzheimer's and Parkinson's diseases.
Nakamura T; Lipton SA
Apoptosis; 2010 Nov; 15(11):1354-63. PubMed ID: 20177970
[TBL] [Abstract][Full Text] [Related]
13. Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity.
Song W; Chen J; Petrilli A; Liot G; Klinglmayr E; Zhou Y; Poquiz P; Tjong J; Pouladi MA; Hayden MR; Masliah E; Ellisman M; Rouiller I; Schwarzenbacher R; Bossy B; Perkins G; Bossy-Wetzel E
Nat Med; 2011 Mar; 17(3):377-82. PubMed ID: 21336284
[TBL] [Abstract][Full Text] [Related]
14. Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation.
Akhtar MW; Sanz-Blasco S; Dolatabadi N; Parker J; Chon K; Lee MS; Soussou W; McKercher SR; Ambasudhan R; Nakamura T; Lipton SA
Nat Commun; 2016 Jan; 7():10242. PubMed ID: 26743041
[TBL] [Abstract][Full Text] [Related]
15. Aqua-soluble DDQ reduces the levels of Drp1 and Aβ and inhibits abnormal interactions between Aβ and Drp1 and protects Alzheimer's disease neurons from Aβ- and Drp1-induced mitochondrial and synaptic toxicities.
Kuruva CS; Manczak M; Yin X; Ogunmokun G; Reddy AP; Reddy PH
Hum Mol Genet; 2017 Sep; 26(17):3375-3395. PubMed ID: 28854701
[TBL] [Abstract][Full Text] [Related]
16. Multiple faces of dynamin-related protein 1 and its role in Alzheimer's disease pathogenesis.
Kandimalla R; Reddy PH
Biochim Biophys Acta; 2016 Apr; 1862(4):814-828. PubMed ID: 26708942
[TBL] [Abstract][Full Text] [Related]
17. Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease.
Shirendeb UP; Calkins MJ; Manczak M; Anekonda V; Dufour B; McBride JL; Mao P; Reddy PH
Hum Mol Genet; 2012 Jan; 21(2):406-20. PubMed ID: 21997870
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model.
Baek SH; Park SJ; Jeong JI; Kim SH; Han J; Kyung JW; Baik SH; Choi Y; Choi BY; Park JS; Bahn G; Shin JH; Jo DS; Lee JY; Jang CG; Arumugam TV; Kim J; Han JW; Koh JY; Cho DH; Jo DG
J Neurosci; 2017 May; 37(20):5099-5110. PubMed ID: 28432138
[TBL] [Abstract][Full Text] [Related]
19. Increased mitochondrial fission and neuronal dysfunction in Huntington's disease: implications for molecular inhibitors of excessive mitochondrial fission.
Reddy PH
Drug Discov Today; 2014 Jul; 19(7):951-5. PubMed ID: 24681059
[TBL] [Abstract][Full Text] [Related]
20. Mitochondrial dynamics in neurodegeneration.
Itoh K; Nakamura K; Iijima M; Sesaki H
Trends Cell Biol; 2013 Feb; 23(2):64-71. PubMed ID: 23159640
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]