BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 20451502)

  • 1. The role of the N-terminus of mammalian copper transporter 1 in the cellular accumulation of cisplatin.
    Larson CA; Adams PL; Jandial DD; Blair BG; Safaei R; Howell SB
    Biochem Pharmacol; 2010 Aug; 80(4):448-54. PubMed ID: 20451502
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of the methionines and histidines in the transmembrane domain of mammalian copper transporter 1 in the cellular accumulation of cisplatin.
    Larson CA; Adams PL; Blair BG; Safaei R; Howell SB
    Mol Pharmacol; 2010 Sep; 78(3):333-9. PubMed ID: 20519567
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A re-evaluation of the role of hCTR1, the human high-affinity copper transporter, in platinum-drug entry into human cells.
    Ivy KD; Kaplan JH
    Mol Pharmacol; 2013 Jun; 83(6):1237-46. PubMed ID: 23543413
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanistic comparison of human high-affinity copper transporter 1-mediated transport between copper ion and cisplatin.
    Liang ZD; Stockton D; Savaraj N; Tien Kuo M
    Mol Pharmacol; 2009 Oct; 76(4):843-53. PubMed ID: 19570948
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of human copper transporter Ctr1 in the transport of platinum-based antitumor agents in cisplatin-sensitive and cisplatin-resistant cells.
    Song IS; Savaraj N; Siddik ZH; Liu P; Wei Y; Wu CJ; Kuo MT
    Mol Cancer Ther; 2004 Dec; 3(12):1543-9. PubMed ID: 15634647
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cisplatin stabilizes a multimeric complex of the human Ctr1 copper transporter: requirement for the extracellular methionine-rich clusters.
    Guo Y; Smith K; Petris MJ
    J Biol Chem; 2004 Nov; 279(45):46393-9. PubMed ID: 15326162
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular modulation of the copper and cisplatin transport function of CTR1 and its interaction with IRS-4.
    Tsai CY; Larson CA; Safaei R; Howell SB
    Biochem Pharmacol; 2014 Aug; 90(4):379-87. PubMed ID: 24967972
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Overcoming platinum drug resistance with copper-lowering agents.
    Chen HH; Kuo MT
    Anticancer Res; 2013 Oct; 33(10):4157-61. PubMed ID: 24122978
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Elevated glutathione levels confer cellular sensitization to cisplatin toxicity by up-regulation of copper transporter hCtr1.
    Chen HH; Song IS; Hossain A; Choi MK; Yamane Y; Liang ZD; Lu J; Wu LY; Siddik ZH; Klomp LW; Savaraj N; Kuo MT
    Mol Pharmacol; 2008 Sep; 74(3):697-704. PubMed ID: 18523133
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparison between copper and cisplatin transport mediated by human copper transporter 1 (hCTR1).
    Du X; Wang X; Li H; Sun H
    Metallomics; 2012 Jul; 4(7):679-85. PubMed ID: 22552365
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanistic basis for overcoming platinum resistance using copper chelating agents.
    Liang ZD; Long Y; Tsai WB; Fu S; Kurzrock R; Gagea-Iurascu M; Zhang F; Chen HH; Hennessy BT; Mills GB; Savaraj N; Kuo MT
    Mol Cancer Ther; 2012 Nov; 11(11):2483-94. PubMed ID: 22914438
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The copper influx transporter human copper transport protein 1 regulates the uptake of cisplatin in human ovarian carcinoma cells.
    Holzer AK; Samimi G; Katano K; Naerdemann W; Lin X; Safaei R; Howell SB
    Mol Pharmacol; 2004 Oct; 66(4):817-23. PubMed ID: 15229296
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Copper transporter 2 regulates the cellular accumulation and cytotoxicity of Cisplatin and Carboplatin.
    Blair BG; Larson CA; Safaei R; Howell SB
    Clin Cancer Res; 2009 Jul; 15(13):4312-21. PubMed ID: 19509135
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of the mammalian copper transporter 1 in the cellular accumulation of platinum-based drugs.
    Larson CA; Blair BG; Safaei R; Howell SB
    Mol Pharmacol; 2009 Feb; 75(2):324-30. PubMed ID: 18996970
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Distinct mechanisms for Ctr1-mediated copper and cisplatin transport.
    Sinani D; Adle DJ; Kim H; Lee J
    J Biol Chem; 2007 Sep; 282(37):26775-26785. PubMed ID: 17627943
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stable plasma membrane levels of hCTR1 mediate cellular copper uptake.
    Eisses JF; Chi Y; Kaplan JH
    J Biol Chem; 2005 Mar; 280(10):9635-9. PubMed ID: 15634665
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of methionine-rich clusters that regulate copper-stimulated endocytosis of the human Ctr1 copper transporter.
    Guo Y; Smith K; Lee J; Thiele DJ; Petris MJ
    J Biol Chem; 2004 Apr; 279(17):17428-33. PubMed ID: 14976198
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rate and regulation of copper transport by human copper transporter 1 (hCTR1).
    Maryon EB; Molloy SA; Ivy K; Yu H; Kaplan JH
    J Biol Chem; 2013 Jun; 288(25):18035-46. PubMed ID: 23658018
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of the high-affinity copper transporter (hCtr1) expression by cisplatin and heavy metals.
    Liang ZD; Long Y; Chen HH; Savaraj N; Kuo MT
    J Biol Inorg Chem; 2014 Jan; 19(1):17-27. PubMed ID: 24132751
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhanced delivery of cisplatin to intraperitoneal ovarian carcinomas mediated by the effects of bortezomib on the human copper transporter 1.
    Jandial DD; Farshchi-Heydari S; Larson CA; Elliott GI; Wrasidlo WJ; Howell SB
    Clin Cancer Res; 2009 Jan; 15(2):553-60. PubMed ID: 19147760
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.