BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

506 related articles for article (PubMed ID: 20459702)

  • 21. A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells.
    Lin L; Hutzen B; Li PK; Ball S; Zuo M; DeAngelis S; Foust E; Sobo M; Friedman L; Bhasin D; Cen L; Li C; Lin J
    Neoplasia; 2010 Jan; 12(1):39-50. PubMed ID: 20072652
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid induces apoptosis of human myeloid leukemia cells by a caspase-8-dependent mechanism.
    Ito Y; Pandey P; Place A; Sporn MB; Gribble GW; Honda T; Kharbanda S; Kufe D
    Cell Growth Differ; 2000 May; 11(5):261-7. PubMed ID: 10845427
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Triterpenoid CDDO-methyl ester inhibits the Janus-activated kinase-1 (JAK1)-->signal transducer and activator of transcription-3 (STAT3) pathway by direct inhibition of JAK1 and STAT3.
    Ahmad R; Raina D; Meyer C; Kufe D
    Cancer Res; 2008 Apr; 68(8):2920-6. PubMed ID: 18413761
    [TBL] [Abstract][Full Text] [Related]  

  • 24. CDDO-Me inhibits proliferation, induces apoptosis, down-regulates Akt, mTOR, NF-kappaB and NF-kappaB-regulated antiapoptotic and proangiogenic proteins in TRAMP prostate cancer cells.
    Deeb D; Gao X; Dulchavsky SA; Gautam SC
    J Exp Ther Oncol; 2008; 7(1):31-9. PubMed ID: 18472640
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Ginkgetin exerts growth inhibitory and apoptotic effects on osteosarcoma cells through inhibition of STAT3 and activation of caspase-3/9.
    Xiong M; Wang L; Yu HL; Han H; Mao D; Chen J; Zeng Y; He N; Liu ZG; Wang ZY; Xu SJ; Guo LY; Wang YA
    Oncol Rep; 2016 Feb; 35(2):1034-40. PubMed ID: 26573608
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling.
    Gao X; Liu Y; Deeb D; Arbab AS; Guo AM; Dulchavsky SA; Gautam SC
    Anticancer Res; 2011 Nov; 31(11):3673-81. PubMed ID: 22110186
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Telomerase reverse transcriptase (TERT) is a therapeutic target of oleanane triterpenoid CDDO-Me in prostate cancer.
    Liu Y; Gao X; Deeb D; Arbab AS; Gautam SC
    Molecules; 2012 Dec; 17(12):14795-809. PubMed ID: 23519253
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Capsaicin is a novel blocker of constitutive and interleukin-6-inducible STAT3 activation.
    Bhutani M; Pathak AK; Nair AS; Kunnumakkara AB; Guha S; Sethi G; Aggarwal BB
    Clin Cancer Res; 2007 May; 13(10):3024-32. PubMed ID: 17505005
    [TBL] [Abstract][Full Text] [Related]  

  • 29. MicroRNA-221 Upregulates the Expression of P-gp and Bcl-2 by Activating the Stat3 Pathway to Promote Doxorubicin Resistance in Osteosarcoma Cells.
    Liu Y; Liu X; Yang S
    Biol Pharm Bull; 2021 Jun; 44(6):861-868. PubMed ID: 33828027
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism.
    Ito Y; Pandey P; Sporn MB; Datta R; Kharbanda S; Kufe D
    Mol Pharmacol; 2001 May; 59(5):1094-9. PubMed ID: 11306692
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cryptotanshinone potentiates the antitumor effects of doxorubicin on gastric cancer cells via inhibition of STAT3 activity.
    Wang J; Zhang G; Dai C; Gao X; Wu J; Shen L; Chen Z; Liu P
    J Int Med Res; 2017 Feb; 45(1):220-230. PubMed ID: 28222632
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells by independently targeting pro-survival Akt and mTOR.
    Deeb D; Gao X; Jiang H; Dulchavsky SA; Gautam SC
    Prostate; 2009 Jun; 69(8):851-60. PubMed ID: 19189297
    [TBL] [Abstract][Full Text] [Related]  

  • 33. c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells.
    Zou W; Liu X; Yue P; Zhou Z; Sporn MB; Lotan R; Khuri FR; Sun SY
    Cancer Res; 2004 Oct; 64(20):7570-8. PubMed ID: 15492284
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia.
    Konopleva M; Tsao T; Estrov Z; Lee RM; Wang RY; Jackson CE; McQueen T; Monaco G; Munsell M; Belmont J; Kantarjian H; Sporn MB; Andreeff M
    Cancer Res; 2004 Nov; 64(21):7927-35. PubMed ID: 15520199
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Quercetin induces caspase-dependent extrinsic apoptosis through inhibition of signal transducer and activator of transcription 3 signaling in HER2-overexpressing BT-474 breast cancer cells.
    Seo HS; Ku JM; Choi HS; Choi YK; Woo JK; Kim M; Kim I; Na CH; Hur H; Jang BH; Shin YC; Ko SG
    Oncol Rep; 2016 Jul; 36(1):31-42. PubMed ID: 27175602
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Isoliquiritigenin inhibits the proliferation of human renal carcinoma Caki cells through the ROS-mediated regulation of the Jak2/STAT3 pathway.
    Kim DH; Park JE; Chae IG; Park G; Lee S; Chun KS
    Oncol Rep; 2017 Jul; 38(1):575-583. PubMed ID: 28560439
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells.
    Park KW; Kundu J; Chae IG; Kim DH; Yu MH; Kundu JK; Chun KS
    Int J Oncol; 2014 Apr; 44(4):1309-15. PubMed ID: 24481553
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Avicin D selectively induces apoptosis and downregulates p-STAT-3, bcl-2, and survivin in cutaneous T-cell lymphoma cells.
    Zhang C; Li B; Gaikwad AS; Haridas V; Xu Z; Gutterman JU; Duvic M
    J Invest Dermatol; 2008 Nov; 128(11):2728-2735. PubMed ID: 18496567
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation.
    Liu DB; Hu GY; Long GX; Qiu H; Mei Q; Hu GQ
    Acta Pharmacol Sin; 2012 May; 33(5):682-90. PubMed ID: 22504904
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Combining the FLT3 inhibitor PKC412 and the triterpenoid CDDO-Me synergistically induces apoptosis in acute myeloid leukemia with the internal tandem duplication mutation.
    Ahmad R; Liu S; Weisberg E; Nelson E; Galinsky I; Meyer C; Kufe D; Kharbanda S; Stone R
    Mol Cancer Res; 2010 Jul; 8(7):986-93. PubMed ID: 20571062
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 26.