These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

286 related articles for article (PubMed ID: 20462952)

  • 1. Ubr1 and Ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins.
    Nillegoda NB; Theodoraki MA; Mandal AK; Mayo KJ; Ren HY; Sultana R; Wu K; Johnson J; Cyr DM; Caplan AJ
    Mol Biol Cell; 2010 Jul; 21(13):2102-16. PubMed ID: 20462952
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Type II Hsp40 Sis1 cooperates with Hsp70 and the E3 ligase Ubr1 to promote degradation of terminally misfolded cytosolic protein.
    Summers DW; Wolfe KJ; Ren HY; Cyr DM
    PLoS One; 2013; 8(1):e52099. PubMed ID: 23341891
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Direct involvement of Hsp70 ATP hydrolysis in Ubr1-dependent quality control.
    Singh A; Vashistha N; Heck J; Tang X; Wipf P; Brodsky JL; Hampton RY
    Mol Biol Cell; 2020 Nov; 31(24):2669-2686. PubMed ID: 32966159
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A network of ubiquitin ligases is important for the dynamics of misfolded protein aggregates in yeast.
    Theodoraki MA; Nillegoda NB; Saini J; Caplan AJ
    J Biol Chem; 2012 Jul; 287(28):23911-22. PubMed ID: 22593585
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Previously unknown role for the ubiquitin ligase Ubr1 in endoplasmic reticulum-associated protein degradation.
    Stolz A; Besser S; Hottmann H; Wolf DH
    Proc Natl Acad Sci U S A; 2013 Sep; 110(38):15271-6. PubMed ID: 23988329
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hsp70 nucleotide exchange factor Fes1 is essential for ubiquitin-dependent degradation of misfolded cytosolic proteins.
    Gowda NK; Kandasamy G; Froehlich MS; Dohmen RJ; Andréasson C
    Proc Natl Acad Sci U S A; 2013 Apr; 110(15):5975-80. PubMed ID: 23530227
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1.
    Eisele F; Wolf DH
    FEBS Lett; 2008 Dec; 582(30):4143-6. PubMed ID: 19041308
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Degradation Signals for Ubiquitin-Proteasome Dependent Cytosolic Protein Quality Control (CytoQC) in Yeast.
    Maurer MJ; Spear ED; Yu AT; Lee EJ; Shahzad S; Michaelis S
    G3 (Bethesda); 2016 Jul; 6(7):1853-66. PubMed ID: 27172186
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rpn4 is a physiological substrate of the Ubr2 ubiquitin ligase.
    Wang L; Mao X; Ju D; Xie Y
    J Biol Chem; 2004 Dec; 279(53):55218-23. PubMed ID: 15504724
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular mass as a determinant for nuclear San1-dependent targeting of misfolded cytosolic proteins to proteasomal degradation.
    Amm I; Wolf DH
    FEBS Lett; 2016 Jun; 590(12):1765-75. PubMed ID: 27173001
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural insights into Ubr1-mediated N-degron polyubiquitination.
    Pan M; Zheng Q; Wang T; Liang L; Mao J; Zuo C; Ding R; Ai H; Xie Y; Si D; Yu Y; Liu L; Zhao M
    Nature; 2021 Dec; 600(7888):334-338. PubMed ID: 34789879
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Absence of the Yeast Hsp31 Chaperones of the DJ-1 Superfamily Perturbs Cytoplasmic Protein Quality Control in Late Growth Phase.
    Amm I; Norell D; Wolf DH
    PLoS One; 2015; 10(10):e0140363. PubMed ID: 26466368
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The ubiquitin ligase E6-AP is induced and recruited to aggresomes in response to proteasome inhibition and may be involved in the ubiquitination of Hsp70-bound misfolded proteins.
    Mishra A; Godavarthi SK; Maheshwari M; Goswami A; Jana NR
    J Biol Chem; 2009 Apr; 284(16):10537-45. PubMed ID: 19233847
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The extent of Ssa1/Ssa2 Hsp70 chaperone involvement in nuclear protein quality control degradation varies with the substrate.
    Jones RD; Enam C; Ibarra R; Borror HR; Mostoller KE; Fredrickson EK; Lin J; Chuang E; March Z; Shorter J; Ravid T; Kleiger G; Gardner RG
    Mol Biol Cell; 2020 Feb; 31(3):221-233. PubMed ID: 31825716
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Five enzymes of the Arg/N-degron pathway form a targeting complex: The concept of superchanneling.
    Oh JH; Hyun JY; Chen SJ; Varshavsky A
    Proc Natl Acad Sci U S A; 2020 May; 117(20):10778-10788. PubMed ID: 32366662
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hsp70 targets a cytoplasmic quality control substrate to the San1p ubiquitin ligase.
    Guerriero CJ; Weiberth KF; Brodsky JL
    J Biol Chem; 2013 Jun; 288(25):18506-20. PubMed ID: 23653356
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HSP70-binding motifs function as protein quality control degrons.
    Abildgaard AB; Voutsinos V; Petersen SD; Larsen FB; Kampmeyer C; Johansson KE; Stein A; Ravid T; Andréasson C; Jensen MK; Lindorff-Larsen K; Hartmann-Petersen R
    Cell Mol Life Sci; 2023 Jan; 80(1):32. PubMed ID: 36609589
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deubiquitinase activity is required for the proteasomal degradation of misfolded cytosolic proteins upon heat-stress.
    Fang NN; Zhu M; Rose A; Wu KP; Mayor T
    Nat Commun; 2016 Oct; 7():12907. PubMed ID: 27698423
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prefoldin Promotes Proteasomal Degradation of Cytosolic Proteins with Missense Mutations by Maintaining Substrate Solubility.
    Comyn SA; Young BP; Loewen CJ; Mayor T
    PLoS Genet; 2016 Jul; 12(7):e1006184. PubMed ID: 27448207
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytosolic splice isoform of Hsp70 nucleotide exchange factor Fes1 is required for the degradation of misfolded proteins in yeast.
    Gowda NK; Kaimal JM; Masser AE; Kang W; Friedländer MR; Andréasson C
    Mol Biol Cell; 2016 Apr; 27(8):1210-9. PubMed ID: 26912797
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.