BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 20463309)

  • 1. In vitro and in vivo inhibition of neuroblastoma tumor cell growth by AKT inhibitor perifosine.
    Li Z; Tan F; Liewehr DJ; Steinberg SM; Thiele CJ
    J Natl Cancer Inst; 2010 Jun; 102(11):758-70. PubMed ID: 20463309
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Perifosine-induced inhibition of Akt attenuates brain-derived neurotrophic factor/TrkB-induced chemoresistance in neuroblastoma in vivo.
    Li Z; Oh DY; Nakamura K; Thiele CJ
    Cancer; 2011 Dec; 117(23):5412-22. PubMed ID: 21590687
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Getting into the AKT.
    Brodeur GM
    J Natl Cancer Inst; 2010 Jun; 102(11):747-9. PubMed ID: 20463308
    [No Abstract]   [Full Text] [Related]  

  • 4. The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.
    Elrod HA; Lin YD; Yue P; Wang X; Lonial S; Khuri FR; Sun SY
    Mol Cancer Ther; 2007 Jul; 6(7):2029-38. PubMed ID: 17604333
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A phase I/Ib trial targeting the Pi3k/Akt pathway using perifosine: Long-term progression-free survival of patients with resistant neuroblastoma.
    Kushner BH; Cheung NV; Modak S; Becher OJ; Basu EM; Roberts SS; Kramer K; Dunkel IJ
    Int J Cancer; 2017 Jan; 140(2):480-484. PubMed ID: 27649927
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antitumor activity of the selective MDM2 antagonist nutlin-3 against chemoresistant neuroblastoma with wild-type p53.
    Van Maerken T; Ferdinande L; Taildeman J; Lambertz I; Yigit N; Vercruysse L; Rihani A; Michaelis M; Cinatl J; Cuvelier CA; Marine JC; De Paepe A; Bracke M; Speleman F; Vandesompele J
    J Natl Cancer Inst; 2009 Nov; 101(22):1562-74. PubMed ID: 19903807
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Preclinical evaluation of perifosine as a potential promising anti-rhabdomyosarcoma agent.
    Shen J; Hong Y; Zhao Q; Zhang JL
    Tumour Biol; 2016 Jan; 37(1):1025-33. PubMed ID: 26269112
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The alkylphospholipid perifosine induces apoptosis and p21-mediated cell cycle arrest in medulloblastoma.
    Kumar A; Fillmore HL; Kadian R; Broaddus WC; Tye GW; Van Meter TE
    Mol Cancer Res; 2009 Nov; 7(11):1813-21. PubMed ID: 19887560
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Perifosine inhibits growth of human experimental endometrial cancers by blockade of AKT phosphorylation.
    Engel JB; Honig A; Schönhals T; Weidler C; Häusler S; Krockenberger M; Grunewald TG; Dombrowski Y; Rieger L; Dietl J; Wischhusen J
    Eur J Obstet Gynecol Reprod Biol; 2008 Nov; 141(1):64-9. PubMed ID: 18687514
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Perifosine induces protective autophagy and upregulation of ATG5 in human chronic myelogenous leukemia cells in vitro.
    Tong Y; Liu YY; You LS; Qian WB
    Acta Pharmacol Sin; 2012 Apr; 33(4):542-50. PubMed ID: 22407228
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Perifosine and sorafenib combination induces mitochondrial cell death and antitumor effects in NOD/SCID mice with Hodgkin lymphoma cell line xenografts.
    Locatelli SL; Giacomini A; Guidetti A; Cleris L; Mortarini R; Anichini A; Gianni AM; Carlo-Stella C
    Leukemia; 2013 Aug; 27(8):1677-87. PubMed ID: 23360848
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells.
    Hideshima T; Catley L; Raje N; Chauhan D; Podar K; Mitsiades C; Tai YT; Vallet S; Kiziltepe T; Ocio E; Ikeda H; Okawa Y; Hideshima H; Munshi NC; Yasui H; Richardson PG; Anderson KC
    Br J Haematol; 2007 Sep; 138(6):783-91. PubMed ID: 17760810
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.
    Cirstea D; Hideshima T; Rodig S; Santo L; Pozzi S; Vallet S; Ikeda H; Perrone G; Gorgun G; Patel K; Desai N; Sportelli P; Kapoor S; Vali S; Mukherjee S; Munshi NC; Anderson KC; Raje N
    Mol Cancer Ther; 2010 Apr; 9(4):963-75. PubMed ID: 20371718
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of Akt by the alkylphospholipid perifosine does not enhance the radiosensitivity of human glioma cells.
    de la Peña L; Burgan WE; Carter DJ; Hollingshead MG; Satyamitra M; Camphausen K; Tofilon PJ
    Mol Cancer Ther; 2006 Jun; 5(6):1504-10. PubMed ID: 16818509
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phase I study of perifosine monotherapy in patients with recurrent or refractory neuroblastoma.
    Matsumoto K; Shichino H; Kawamoto H; Kosaka Y; Chin M; Kato K; Mugishima H
    Pediatr Blood Cancer; 2017 Nov; 64(11):. PubMed ID: 28521076
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synergistic proapoptotic activity of recombinant TRAIL plus the Akt inhibitor Perifosine in acute myelogenous leukemia cells.
    Tazzari PL; Tabellini G; Ricci F; Papa V; Bortul R; Chiarini F; Evangelisti C; Martinelli G; Bontadini A; Cocco L; McCubrey JA; Martelli AM
    Cancer Res; 2008 Nov; 68(22):9394-403. PubMed ID: 19010914
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PI3K Inhibitor Combined With Chemotherapy Can Enhance the Apoptosis of Neuroblastoma Cells In Vitro and In Vivo.
    Geng X; Xie L; Xing H
    Technol Cancer Res Treat; 2016 Oct; 15(5):716-22. PubMed ID: 26224681
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Perifosine, an AKT inhibitor, modulates ovarian cancer cell line sensitivity to cisplatin-induced growth arrest.
    Al Sawah E; Chen X; Marchion DC; Xiong Y; Ramirez IJ; Abbasi F; Bou Zgheib N; Chon HS; Wenham RM; Apte SM; Judson PL; Lancaster JM
    Gynecol Oncol; 2013 Oct; 131(1):207-12. PubMed ID: 23877012
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tolcapone induces oxidative stress leading to apoptosis and inhibition of tumor growth in Neuroblastoma.
    Maser T; Rich M; Hayes D; Zhao P; Nagulapally AB; Bond J; Saulnier Sholler G
    Cancer Med; 2017 Jun; 6(6):1341-1352. PubMed ID: 28429453
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Combination of an allosteric Akt Inhibitor MK-2206 with etoposide or rapamycin enhances the antitumor growth effect in neuroblastoma.
    Li Z; Yan S; Attayan N; Ramalingam S; Thiele CJ
    Clin Cancer Res; 2012 Jul; 18(13):3603-15. PubMed ID: 22550167
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.