158 related articles for article (PubMed ID: 20463925)
1. A novel synthetic analog of 5, 8-disubstituted quinazolines blocks mitosis and induces apoptosis of tumor cells by inhibiting microtubule polymerization.
Tian W; Qin L; Song Q; He L; Ai M; Jin Y; Zhou Z; You S; Long Y; Yu Q
PLoS One; 2010 May; 5(5):e10499. PubMed ID: 20463925
[TBL] [Abstract][Full Text] [Related]
2. NMK-BH2, a novel microtubule-depolymerising bis (indolyl)-hydrazide-hydrazone, induces apoptotic and autophagic cell death in cervical cancer cells by binding to tubulin at colchicine - site.
Das Mukherjee D; Kumar NM; Tantak MP; Datta S; Ghosh Dastidar D; Kumar D; Chakrabarti G
Biochim Biophys Acta Mol Cell Res; 2020 Oct; 1867(10):118762. PubMed ID: 32502617
[TBL] [Abstract][Full Text] [Related]
3. MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules.
Zhang Z; Meng T; He J; Li M; Tong LJ; Xiong B; Lin L; Shen J; Miao ZH; Ding J
Invest New Drugs; 2010 Dec; 28(6):715-28. PubMed ID: 19705064
[TBL] [Abstract][Full Text] [Related]
4. Selective Inhibition of Spindle Microtubules by a Tubulin-Binding Quinazoline Derivative.
Sawada JI; Ishii H; Matsuno K; Sato M; Suzuki Y; Asai A
Mol Pharmacol; 2019 Nov; 96(5):609-618. PubMed ID: 31471455
[TBL] [Abstract][Full Text] [Related]
5. Thymoquinone inhibits microtubule polymerization by tubulin binding and causes mitotic arrest following apoptosis in A549 cells.
Acharya BR; Chatterjee A; Ganguli A; Bhattacharya S; Chakrabarti G
Biochimie; 2014 Feb; 97():78-91. PubMed ID: 24113316
[TBL] [Abstract][Full Text] [Related]
6. Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis.
Jordan MA; Thrower D; Wilson L
J Cell Sci; 1992 Jul; 102 ( Pt 3)():401-16. PubMed ID: 1506423
[TBL] [Abstract][Full Text] [Related]
7. Indirubin, a bis-indole alkaloid binds to tubulin and exhibits antimitotic activity against HeLa cells in synergism with vinblastine.
Mohan L; Raghav D; Ashraf SM; Sebastian J; Rathinasamy K
Biomed Pharmacother; 2018 Sep; 105():506-517. PubMed ID: 29883946
[TBL] [Abstract][Full Text] [Related]
8. 6α-Acetoxyanopterine: A Novel Structure Class of Mitotic Inhibitor Disrupting Microtubule Dynamics in Prostate Cancer Cells.
Levrier C; Sadowski MC; Rockstroh A; Gabrielli B; Kavallaris M; Lehman M; Davis RA; Nelson CC
Mol Cancer Ther; 2017 Jan; 16(1):3-15. PubMed ID: 27760837
[TBL] [Abstract][Full Text] [Related]
9. CKT0353, a novel microtubule targeting agent, overcomes paclitaxel induced resistance in cancer cells.
Dinić J; Ríos-Luci C; Karpaviciene I; Cikotiene I; Fernandes MX; Pešić M; Padrón JM
Invest New Drugs; 2020 Jun; 38(3):584-598. PubMed ID: 31177401
[TBL] [Abstract][Full Text] [Related]
10. The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth.
Jordan MA; Kamath K; Manna T; Okouneva T; Miller HP; Davis C; Littlefield BA; Wilson L
Mol Cancer Ther; 2005 Jul; 4(7):1086-95. PubMed ID: 16020666
[TBL] [Abstract][Full Text] [Related]
11. AG11, a novel dichloroflavanone derivative with anti-mitotic activity towards human bladder cancer cells.
Juhem A; Boumendjel A; Touquet B; Guillot A; Popov A; Ronot X; Martel-Frachet V
Anticancer Res; 2013 Oct; 33(10):4445-52. PubMed ID: 24123014
[TBL] [Abstract][Full Text] [Related]
12. A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors.
Tahir SK; Han EK; Credo B; Jae HS; Pietenpol JA; Scatena CD; Wu-Wong JR; Frost D; Sham H; Rosenberg SH; Ng SC
Cancer Res; 2001 Jul; 61(14):5480-5. PubMed ID: 11454695
[TBL] [Abstract][Full Text] [Related]
13. Tubulin-based antimitotic mechanism of E7974, a novel analogue of the marine sponge natural product hemiasterlin.
Kuznetsov G; TenDyke K; Towle MJ; Cheng H; Liu J; Marsh JP; Schiller SE; Spyvee MR; Yang H; Seletsky BM; Shaffer CJ; Marceau V; Yao Y; Suh EM; Campagna S; Fang FG; Kowalczyk JJ; Littlefield BA
Mol Cancer Ther; 2009 Oct; 8(10):2852-60. PubMed ID: 19825803
[TBL] [Abstract][Full Text] [Related]
14. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules.
Kamath K; Okouneva T; Larson G; Panda D; Wilson L; Jordan MA
Mol Cancer Ther; 2006 Sep; 5(9):2225-33. PubMed ID: 16985056
[TBL] [Abstract][Full Text] [Related]
15. The small molecule CS1 inhibits mitosis and sister chromatid resolution in HeLa cells.
Wu X; Li Z; Shen Y
Biochim Biophys Acta Gen Subj; 2018 May; 1862(5):1134-1147. PubMed ID: 29410075
[TBL] [Abstract][Full Text] [Related]
16. 3-(Iodoacetamido)-benzoylurea: a novel cancericidal tubulin ligand that inhibits microtubule polymerization, phosphorylates bcl-2, and induces apoptosis in tumor cells.
Jiang JD; Davis AS; Middleton K; Ling YH; Perez-Soler R; Holland JF; Bekesi JG
Cancer Res; 1998 Dec; 58(23):5389-95. PubMed ID: 9850070
[TBL] [Abstract][Full Text] [Related]
17. The design, synthesis and evaluation of selenium-containing 4-anilinoquinazoline hybrids as anticancer agents and a study of their mechanism.
An B; Zhang S; Hu J; Pan T; Huang L; Tang JC; Li X; Chan ASC
Org Biomol Chem; 2018 Jul; 16(25):4701-4714. PubMed ID: 29900452
[TBL] [Abstract][Full Text] [Related]
18. Structure-based virtual screening of novel tubulin inhibitors and their characterization as anti-mitotic agents.
Kim ND; Park ES; Kim YH; Moon SK; Lee SS; Ahn SK; Yu DY; No KT; Kim KH
Bioorg Med Chem; 2010 Oct; 18(19):7092-100. PubMed ID: 20810285
[TBL] [Abstract][Full Text] [Related]
19. Suppression of microtubule dynamic instability and turnover in MCF7 breast cancer cells by sulforaphane.
Azarenko O; Okouneva T; Singletary KW; Jordan MA; Wilson L
Carcinogenesis; 2008 Dec; 29(12):2360-8. PubMed ID: 18952594
[TBL] [Abstract][Full Text] [Related]
20. Characterization of a recently synthesized microtubule-targeting compound that disrupts mitotic spindle poles in human cells.
Jaunky DB; Larocque K; Husser MC; Liu JT; Forgione P; Piekny A
Sci Rep; 2021 Dec; 11(1):23665. PubMed ID: 34880347
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
