These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 20472429)

  • 1. Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV.
    Di Fiore A; Monti SM; Innocenti A; Winum JY; De Simone G; Supuran CT
    Bioorg Med Chem Lett; 2010 Jun; 20(12):3601-5. PubMed ID: 20472429
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib.
    Di Fiore A; Pedone C; D'Ambrosio K; Scozzafava A; De Simone G; Supuran CT
    Bioorg Med Chem Lett; 2006 Jan; 16(2):437-42. PubMed ID: 16290146
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors.
    Temperini C; Innocenti A; Scozzafava A; Parkkila S; Supuran CT
    J Med Chem; 2010 Jan; 53(2):850-4. PubMed ID: 20028100
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies.
    De Simone G; Di Fiore A; Menchise V; Pedone C; Antel J; Casini A; Scozzafava A; Wurl M; Supuran CT
    Bioorg Med Chem Lett; 2005 May; 15(9):2315-20. PubMed ID: 15837316
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hydroxamate represents a versatile zinc binding group for the development of new carbonic anhydrase inhibitors.
    Di Fiore A; Maresca A; Supuran CT; De Simone G
    Chem Commun (Camb); 2012 Sep; 48(70):8838-40. PubMed ID: 22836518
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Carbonic anhydrase inhibitors: X-ray and molecular modeling study for the interaction of a fluorescent antitumor sulfonamide with isozyme II and IX.
    Alterio V; Vitale RM; Monti SM; Pedone C; Scozzafava A; Cecchi A; De Simone G; Supuran CT
    J Am Chem Soc; 2006 Jun; 128(25):8329-35. PubMed ID: 16787097
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors.
    Avvaru BS; Wagner JM; Maresca A; Scozzafava A; Robbins AH; Supuran CT; McKenna R
    Bioorg Med Chem Lett; 2010 Aug; 20(15):4376-81. PubMed ID: 20605094
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of 5-amino-1,3,4-thiadiazole-2-sulfonamide and 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide to human isoform II.
    Menchise V; De Simone G; Di Fiore A; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2006 Dec; 16(24):6204-8. PubMed ID: 17000110
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV.
    Temperini C; Innocenti A; Scozzafava A; Supuran CT
    Bioorg Med Chem; 2008 Sep; 16(18):8373-8. PubMed ID: 18774300
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors.
    Maresca A; Temperini C; Vu H; Pham NB; Poulsen SA; Scozzafava A; Quinn RJ; Supuran CT
    J Am Chem Soc; 2009 Mar; 131(8):3057-62. PubMed ID: 19206230
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I and II, and extracellular isoforms IV, IX, and XII with sulfamides incorporating sugar moieties.
    Colinas PA; Bravo RD; Vullo D; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2007 Sep; 17(18):5086-90. PubMed ID: 17658252
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Carbonic anhydrase inhibitors: the X-ray crystal structure of the adduct of N-hydroxysulfamide with isozyme II explains why this new zinc binding function is effective in the design of potent inhibitors.
    Temperini C; Winum JY; Montero JL; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2007 May; 17(10):2795-801. PubMed ID: 17346964
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Carbonic anhydrase inhibitors. X-ray crystal studies of the carbonic anhydrase II-trithiocarbonate adduct--an inhibitor mimicking the sulfonamide and urea binding to the enzyme.
    Temperini C; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2010 Jan; 20(2):474-8. PubMed ID: 20005709
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nanoscale enzyme inhibitors: fullerenes inhibit carbonic anhydrase by occluding the active site entrance.
    Innocenti A; Durdagi S; Doostdar N; Strom TA; Barron AR; Supuran CT
    Bioorg Med Chem; 2010 Apr; 18(8):2822-8. PubMed ID: 20363143
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Carbonic anhydrase inhibitors: inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides--solution and crystallographic studies.
    Alterio V; De Simone G; Monti SM; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2007 Aug; 17(15):4201-7. PubMed ID: 17540563
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Carbonic anhydrase inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: kinetic and X-ray crystallographic studies.
    Temperini C; Innocenti A; Mastrolorenzo A; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2007 Sep; 17(17):4866-72. PubMed ID: 17588751
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies.
    Temperini C; Cecchi A; Boyle NA; Scozzafava A; Cabeza JE; Wentworth P; Blackburn GM; Supuran CT
    Bioorg Med Chem Lett; 2008 Feb; 18(3):999-1005. PubMed ID: 18162396
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups.
    D'Ambrosio K; Smaine FZ; Carta F; De Simone G; Winum JY; Supuran CT
    J Med Chem; 2012 Aug; 55(15):6776-83. PubMed ID: 22775345
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with L-histidine as a platform for the design of stronger activators.
    Temperini C; Scozzafava A; Puccetti L; Supuran CT
    Bioorg Med Chem Lett; 2005 Dec; 15(23):5136-41. PubMed ID: 16214338
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions.
    Innocenti A; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2009 Apr; 19(7):1855-7. PubMed ID: 19269822
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.