These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 20476738)

  • 1. Synthesis and evaluation of new endomorphin-2 analogues containing (Z)-alpha,beta-didehydrophenylalanine (Delta(Z)Phe) residues.
    Torino D; Mollica A; Pinnen F; Feliciani F; Lucente G; Fabrizi G; Portalone G; Davis P; Lai J; Ma SW; Porreca F; Hruby VJ
    J Med Chem; 2010 Jun; 53(11):4550-4. PubMed ID: 20476738
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of stereoisomeric analogues of endomorphin-2, H-Tyr-Pro-Phe-Phe-NH(2), and examination of their opioid receptor binding activities and solution conformation.
    Okada Y; Fukumizu A; Takahashi M; Shimizu Y; Tsuda Y; Yokoi T; Bryant SD; Lazarus LH
    Biochem Biophys Res Commun; 2000 Sep; 276(1):7-11. PubMed ID: 11006073
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pseudoproline-containing analogues of morphiceptin and endomorphin-2: evidence for a cis Tyr-Pro amide bond in the bioactive conformation.
    Keller M; Boissard C; Patiny L; Chung NN; Lemieux C; Mutter M; Schiller PW
    J Med Chem; 2001 Nov; 44(23):3896-903. PubMed ID: 11689075
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluations of novel endomorphin analogues containing α-hydroxy-β-phenylalanine (AHPBA) displaying mixed μ/δ opioid receptor agonist and δ opioid receptor antagonist activities.
    Hu M; Giulianotti MA; McLaughlin JP; Shao J; Debevec G; Maida LE; Geer P; Cazares M; Misler J; Li L; Dooley C; Ganno ML; Eans SO; Mizrachi E; Santos RG; Yongye AB; Houghten RA; Yu Y
    Eur J Med Chem; 2015 Mar; 92():270-81. PubMed ID: 25559207
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and activity of endomorphin-2 and morphiceptin analogues with proline surrogates in position 2.
    Giordano C; Sansone A; Masi A; Lucente G; Punzi P; Mollica A; Pinnen F; Feliciani F; Cacciatore I; Davis P; Lai J; Ma SW; Porreca F; Hruby V
    Eur J Med Chem; 2010 Oct; 45(10):4594-600. PubMed ID: 20692738
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Development of potent bifunctional endomorphin-2 analogues with mixed mu-/delta-opioid agonist and delta-opioid antagonist properties.
    Fujita Y; Tsuda Y; Li T; Motoyama T; Takahashi M; Shimizu Y; Yokoi T; Sasaki Y; Ambo A; Kita A; Jinsmaa Y; Bryant SD; Lazarus LH; Okada Y
    J Med Chem; 2004 Jul; 47(14):3591-9. PubMed ID: 15214786
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The TIPP opioid peptide family: development of delta antagonists, delta agonists, and mixed mu agonist/delta antagonists.
    Schiller PW; Weltrowska G; Berezowska I; Nguyen TM; Wilkes BC; Lemieux C; Chung NN
    Biopolymers; 1999; 51(6):411-25. PubMed ID: 10797230
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of (Z)-2,3-didehydrophenylalanine and phenylalanine C-terminal residues in determining the chemotactic activity of formylpeptides.
    Torrini I; Zecchini GP; Paradisi MP; Spisani S
    Arch Pharm (Weinheim); 1996 Mar; 329(3):143-8. PubMed ID: 9005813
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design of specific structures using alpha,beta-dehydro-phenylalanine residues: synthesis, crystal structure, and molecular conformation of Boc-L-Val-delta Phe-delta Phe-L-Val-delta Phe-delta Phe-L-Val-OCH3, a 3(10)-helical heptapeptide.
    Mitra SN; Dey S; Karthikeyan S; Singh TP
    Biopolymers; 1997 Jan; 41(1):97-105. PubMed ID: 8986122
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Endomorphin 2 analogues containing Dmp residue as an aromatic amino acid surrogate with high mu-opioid receptor affinity and selectivity.
    Sasaki Y; Sasaki A; Niizuma H; Goto H; Ambo A
    Bioorg Med Chem; 2003 Mar; 11(5):675-8. PubMed ID: 12537996
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural studies of [2',6'-dimethyl-L-tyrosine1]endomorphin-2 analogues: enhanced activity and cis orientation of the Dmt-Pro amide bond.
    Okada Y; Fujita Y; Motoyama T; Tsuda Y; Yokoi T; Li T; Sasaki Y; Ambo A; Jinsmaa Y; Bryant SD; Lazarus LH
    Bioorg Med Chem; 2003 May; 11(9):1983-94. PubMed ID: 12670649
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential stereochemical requirements of mu vs. delta opioid receptors for ligand binding and signal transduction: development of a class of potent and highly delta-selective peptide antagonists.
    Schiller PW; Nguyen TM; Weltrowska G; Wilkes BC; Marsden BJ; Lemieux C; Chung NN
    Proc Natl Acad Sci U S A; 1992 Dec; 89(24):11871-5. PubMed ID: 1334552
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Endomorphin-2 analogs containing modified tyrosines: Biological and theoretical investigation of the influence on conformation and pharmacological profile.
    Wtorek K; Artali R; Piekielna-Ciesielska J; Koszuk J; Kluczyk A; Gentilucci L; Janecka A
    Eur J Med Chem; 2019 Oct; 179():527-536. PubMed ID: 31276897
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, pharmacological evaluation and conformational investigation of endomorphin-2 hybrid analogues.
    Lesma G; Salvadori S; Airaghi F; Bojnik E; Borsodi A; Recca T; Sacchetti A; Balboni G; Silvani A
    Mol Divers; 2013 Feb; 17(1):19-31. PubMed ID: 23124951
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dermorphin tetrapeptide analogues with 2',6'-dimethylphenylalanine (Dmp) substituted for aromatic amino acids have high mu opioid receptor binding and biological activities.
    Ambo A; Niizuma H; Sasaki A; Kohara H; Sasaki Y
    Bioorg Med Chem Lett; 2003 Apr; 13(7):1269-72. PubMed ID: 12657261
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Conformational restriction of the phenylalanine residue in a cyclic opioid peptide analogue: effects on receptor selectivity and stereospecificity.
    Schiller PW; Weltrowska G; Nguyen TM; Lemieux C; Chung NN; Marsden BJ; Wilkes BC
    J Med Chem; 1991 Oct; 34(10):3125-32. PubMed ID: 1656045
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The opioid mu agonist/delta antagonist DIPP-NH(2)[Psi] produces a potent analgesic effect, no physical dependence, and less tolerance than morphine in rats.
    Schiller PW; Fundytus ME; Merovitz L; Weltrowska G; Nguyen TM; Lemieux C; Chung NN; Coderre TJ
    J Med Chem; 1999 Sep; 42(18):3520-6. PubMed ID: 10479285
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Beta-methyl substitution of cyclohexylalanine in Dmt-Tic-Cha-Phe peptides results in highly potent delta opioid antagonists.
    Tóth G; Ioja E; Tömböly C; Ballet S; Tourwé D; Péter A; Martinek T; Chung NN; Schiller PW; Benyhe S; Borsodi A
    J Med Chem; 2007 Jan; 50(2):328-33. PubMed ID: 17228874
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bifunctional [2',6'-dimethyl-L-tyrosine1]endomorphin-2 analogues substituted at position 3 with alkylated phenylalanine derivatives yield potent mixed mu-agonist/delta-antagonist and dual mu-agonist/delta-agonist opioid ligands.
    Li T; Shiotani K; Miyazaki A; Tsuda Y; Ambo A; Sasaki Y; Jinsmaa Y; Marczak E; Bryant SD; Lazarus LH; Okada Y
    J Med Chem; 2007 Jun; 50(12):2753-66. PubMed ID: 17497839
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential receptor binding characteristics of consecutive phenylalanines in micro-opioid specific peptide ligand endomorphin-2.
    Honda T; Shirasu N; Isozaki K; Kawano M; Shigehiro D; Chuman Y; Fujita T; Nose T; Shimohigashi Y
    Bioorg Med Chem; 2007 Jun; 15(11):3883-8. PubMed ID: 17395470
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.