BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

259 related articles for article (PubMed ID: 20479006)

  • 41. Calculation of pathways for the conformational transition between the GTP- and GDP-bound states of the Ha-ras-p21 protein: calculations with explicit solvent simulations and comparison with calculations in vacuum.
    Diaz JF; Wroblowski B; Schlitter J; Engelborghs Y
    Proteins; 1997 Jul; 28(3):434-51. PubMed ID: 9223188
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Mapping the nucleotide-dependent conformational change of human N-ras p21 in solution by heteronuclear-edited proton-observed NMR methods.
    Hu JS; Redfield AG
    Biochemistry; 1993 Jul; 32(26):6763-72. PubMed ID: 8329399
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Shift in the equilibrium between on and off states of the allosteric switch in Ras-GppNHp affected by small molecules and bulk solvent composition.
    Holzapfel G; Buhrman G; Mattos C
    Biochemistry; 2012 Aug; 51(31):6114-26. PubMed ID: 22845804
    [TBL] [Abstract][Full Text] [Related]  

  • 44. X-ray crystal structures of transforming p21 ras mutants suggest a transition-state stabilization mechanism for GTP hydrolysis.
    Privé GG; Milburn MV; Tong L; de Vos AM; Yamaizumi Z; Nishimura S; Kim SH
    Proc Natl Acad Sci U S A; 1992 Apr; 89(8):3649-53. PubMed ID: 1565661
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Biological and structural characterization of a Ras transforming mutation at the phenylalanine-156 residue, which is conserved in all members of the Ras superfamily.
    Quilliam LA; Zhong S; Rabun KM; Carpenter JW; South TL; Der CJ; Campbell-Burk S
    Proc Natl Acad Sci U S A; 1995 Feb; 92(5):1272-6. PubMed ID: 7877967
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Mechanism of free radical nitric oxide-mediated Ras guanine nucleotide dissociation.
    Heo J; Prutzman KC; Mocanu V; Campbell SL
    J Mol Biol; 2005 Mar; 346(5):1423-40. PubMed ID: 15713491
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Mechanisms of guanosine triphosphate hydrolysis by Ras and Ras-GAP proteins as rationalized by ab initio QM/MM simulations.
    Grigorenko BL; Nemukhin AV; Shadrina MS; Topol IA; Burt SK
    Proteins; 2007 Feb; 66(2):456-66. PubMed ID: 17094109
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Allostery and dynamics in small G proteins.
    Mott HR; Owen D
    Biochem Soc Trans; 2018 Oct; 46(5):1333-1343. PubMed ID: 30301845
    [TBL] [Abstract][Full Text] [Related]  

  • 49. NMR
    Yuan C; Hansen AL; Bruschweiler-Li L; Brüschweiler R
    Biomol NMR Assign; 2024 Jun; 18(1):7-13. PubMed ID: 37948018
    [TBL] [Abstract][Full Text] [Related]  

  • 50. NMR
    Sharma AK; Dyba M; Tonelli M; Smith B; Gillette WK; Esposito D; Nissley DV; McCormick F; Maciag AE
    Biomol NMR Assign; 2022 Apr; 16(1):1-8. PubMed ID: 34686998
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Conformation change of effector-region residues in antiparallel beta-sheet of human c-Ha-ras protein on GDP----GTP gamma S exchange: a two-dimensional NMR study.
    Yamasaki K; Kawai G; Ito Y; Muto Y; Fujita J; Miyazawa T; Nishimura S; Yokoyama S
    Biochem Biophys Res Commun; 1989 Aug; 162(3):1054-62. PubMed ID: 2669742
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras.
    Franken SM; Scheidig AJ; Krengel U; Rensland H; Lautwein A; Geyer M; Scheffzek K; Goody RS; Kalbitzer HR; Pai EF
    Biochemistry; 1993 Aug; 32(33):8411-20. PubMed ID: 8357792
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Monitoring Ras Interactions with the Nucleotide Exchange Factor Son of Sevenless (Sos) Using Site-specific NMR Reporter Signals and Intrinsic Fluorescence.
    Vo U; Vajpai N; Flavell L; Bobby R; Breeze AL; Embrey KJ; Golovanov AP
    J Biol Chem; 2016 Jan; 291(4):1703-1718. PubMed ID: 26565026
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Relation between the conformational heterogeneity and reaction cycle of Ras: molecular simulation of Ras.
    Kobayashi C; Saito S
    Biophys J; 2010 Dec; 99(11):3726-34. PubMed ID: 21112297
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Two Distinct Structures of Membrane-Associated Homodimers of GTP- and GDP-Bound KRAS4B Revealed by Paramagnetic Relaxation Enhancement.
    Lee KY; Fang Z; Enomoto M; Gasmi-Seabrook G; Zheng L; Koide S; Ikura M; Marshall CB
    Angew Chem Int Ed Engl; 2020 Jun; 59(27):11037-11045. PubMed ID: 32227412
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis.
    Schlichting I; Almo SC; Rapp G; Wilson K; Petratos K; Lentfer A; Wittinghofer A; Kabsch W; Pai EF; Petsko GA
    Nature; 1990 May; 345(6273):309-15. PubMed ID: 2111463
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Crystal structure of the Gtr1p(GTP)-Gtr2p(GDP) protein complex reveals large structural rearrangements triggered by GTP-to-GDP conversion.
    Jeong JH; Lee KH; Kim YM; Kim DH; Oh BH; Kim YG
    J Biol Chem; 2012 Aug; 287(35):29648-53. PubMed ID: 22807443
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Revisiting the structural flexibility of the complex p21(ras)-GTP: the catalytic conformation of the molecular switch II.
    Soares TA; Miller JH; Straatsma TP
    Proteins; 2001 Dec; 45(4):297-312. PubMed ID: 11746677
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Characterization of a Ras mutant with identical GDP- and GTP-bound structures .
    Ford B; Boykevisch S; Zhao C; Kunzelmann S; Bar-Sagi D; Herrmann C; Nassar N
    Biochemistry; 2009 Dec; 48(48):11449-57. PubMed ID: 19883123
    [TBL] [Abstract][Full Text] [Related]  

  • 60. The crystal structure of the small GTPase Rab11b reveals critical differences relative to the Rab11a isoform.
    Scapin SM; Carneiro FR; Alves AC; Medrano FJ; Guimarães BG; Zanchin NI
    J Struct Biol; 2006 Jun; 154(3):260-8. PubMed ID: 16545962
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.