BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

106 related articles for article (PubMed ID: 20480085)

  • 1. Modelling the binding of HIV-reverse transcriptase and nevirapine: an assessment of quantum mechanical and force field approaches and predictions of the effect of mutations on binding.
    Raju RK; Burton NA; Hillier IH
    Phys Chem Chem Phys; 2010 Jul; 12(26):7117-25. PubMed ID: 20480085
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effect of a bound non-nucleoside RT inhibitor on the dynamics of wild-type and mutant HIV-1 reverse transcriptase.
    Zhou Z; Madrid M; Evanseck JD; Madura JD
    J Am Chem Soc; 2005 Dec; 127(49):17253-60. PubMed ID: 16332074
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quantum computational analysis for drug resistance of HIV-1 reverse transcriptase to nevirapine through point mutations.
    He X; Mei Y; Xiang Y; Zhang DW; Zhang JZ
    Proteins; 2005 Nov; 61(2):423-32. PubMed ID: 16114038
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138.
    Ren J; Nichols CE; Stamp A; Chamberlain PP; Ferris R; Weaver KL; Short SA; Stammers DK
    FEBS J; 2006 Aug; 273(16):3850-60. PubMed ID: 16911530
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bridge water mediates nevirapine binding to wild type and Y181C HIV-1 reverse transcriptase--evidence from molecular dynamics simulations and MM-PBSA calculations.
    Treesuwan W; Hannongbua S
    J Mol Graph Model; 2009; 27(8):921-9. PubMed ID: 19414275
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Docking-MM-GB/SA and ADME screening of HIV-1 NNRTI inhibitor: nevirapine and its analogues.
    Sengupta D; Verma D; Naik PK
    In Silico Biol; 2008; 8(3-4):275-89. PubMed ID: 19032162
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structures of HIV-1 reverse transcriptases mutated at codons 100, 106 and 108 and mechanisms of resistance to non-nucleoside inhibitors.
    Ren J; Nichols CE; Chamberlain PP; Weaver KL; Short SA; Stammers DK
    J Mol Biol; 2004 Feb; 336(3):569-78. PubMed ID: 15095972
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rational approaches for the design of effective human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitors.
    Ribone SR; Quevedo MA; Madrid M; Briñón MC
    J Chem Inf Model; 2011 Jan; 51(1):130-8. PubMed ID: 21133347
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Study on the interaction between HIV reverse transcriptase and its non-nucleoside inhibitor nevirapine by capillary electrophoresis.
    Chen W; Li W; Ling X; Wang X; Liu J
    J Chromatogr B Analyt Technol Biomed Life Sci; 2010 Jun; 878(20):1714-7. PubMed ID: 20457546
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Docking of non-nucleoside inhibitors: neotripterifordin and its derivatives to HIV-1 reverse transcriptase.
    Zhou Z; Madrid M; Madura JD
    Proteins; 2002 Dec; 49(4):529-42. PubMed ID: 12402361
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The molecular basis of resilience to the effect of the Lys103Asn mutation in non-nucleoside HIV-1 reverse transcriptase inhibitors studied by targeted molecular dynamics simulations.
    Rodríguez-Barrios F; Balzarini J; Gago F
    J Am Chem Soc; 2005 May; 127(20):7570-8. PubMed ID: 15898808
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design of nevirapine derivatives insensitive to the K103N and Y181C HIV-1 reverse transcriptase mutants.
    Saparpakorn P; Hannongbua S; Rognan D
    SAR QSAR Environ Res; 2006 Apr; 17(2):183-94. PubMed ID: 16644557
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors.
    Ren J; Nichols C; Bird L; Chamberlain P; Weaver K; Short S; Stuart DI; Stammers DK
    J Mol Biol; 2001 Sep; 312(4):795-805. PubMed ID: 11575933
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions.
    Maga G; Amacker M; Ruel N; Hübscher U; Spadari S
    J Mol Biol; 1997 Dec; 274(5):738-47. PubMed ID: 9405155
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Understanding the basis of resistance in the irksome Lys103Asn HIV-1 reverse transcriptase mutant through targeted molecular dynamics simulations.
    Rodríguez-Barrios F; Gago F
    J Am Chem Soc; 2004 Dec; 126(47):15386-7. PubMed ID: 15563158
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Relationship of potency and resilience to drug resistant mutations for GW420867X revealed by crystal structures of inhibitor complexes for wild-type, Leu100Ile, Lys101Glu, and Tyr188Cys mutant HIV-1 reverse transcriptases.
    Ren J; Nichols CE; Chamberlain PP; Weaver KL; Short SA; Chan JH; Kleim JP; Stammers DK
    J Med Chem; 2007 May; 50(10):2301-9. PubMed ID: 17441703
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Flexible docking of pyridinone derivatives into the non-nucleoside inhibitor binding site of HIV-1 reverse transcriptase.
    Medina-Franco JL; Rodríguez-Morales S; Juárez-Gordiano C; Hernández-Campos A; Jiménez-Barbero J; Castillo R
    Bioorg Med Chem; 2004 Dec; 12(23):6085-95. PubMed ID: 15519154
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Compensatory role of double mutation N348I/M184V on nevirapine binding landscape: insight from molecular dynamics simulation.
    Karubiu W; Bhakat S; Soliman ME
    Protein J; 2014 Oct; 33(5):432-46. PubMed ID: 25107349
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural basis for drug resistance mechanisms for non-nucleoside inhibitors of HIV reverse transcriptase.
    Ren J; Stammers DK
    Virus Res; 2008 Jun; 134(1-2):157-70. PubMed ID: 18313784
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Estimation of binding affinities for HEPT and nevirapine analogues with HIV-1 reverse transcriptase via Monte Carlo simulations.
    Rizzo RC; Tirado-Rives J; Jorgensen WL
    J Med Chem; 2001 Jan; 44(2):145-54. PubMed ID: 11170624
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.