186 related articles for article (PubMed ID: 20484037)
1. Activation of FOXO3a is sufficient to reverse mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor chemoresistance in human cancer.
Yang JY; Chang CJ; Xia W; Wang Y; Wong KK; Engelman JA; Du Y; Andreeff M; Hortobagyi GN; Hung MC
Cancer Res; 2010 Jun; 70(11):4709-18. PubMed ID: 20484037
[TBL] [Abstract][Full Text] [Related]
2. Apoptosis induction by MEK inhibition in human lung cancer cells is mediated by Bim.
Meng J; Fang B; Liao Y; Chresta CM; Smith PD; Roth JA
PLoS One; 2010 Sep; 5(9):e13026. PubMed ID: 20885957
[TBL] [Abstract][Full Text] [Related]
3. Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells is mediated by c-Jun NH2-terminal kinase and Akt.
Sunters A; Madureira PA; Pomeranz KM; Aubert M; Brosens JJ; Cook SJ; Burgering BM; Coombes RC; Lam EW
Cancer Res; 2006 Jan; 66(1):212-20. PubMed ID: 16397234
[TBL] [Abstract][Full Text] [Related]
4. [Combined inhibition of PI3K and MEK has synergistic inhibitory effect on the proliferation of cisplatin-resistant ovarian cancer cells].
Liu Y; Chen X; Luo Z
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2014 Jun; 30(6):592-6. PubMed ID: 24909280
[TBL] [Abstract][Full Text] [Related]
5. Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines.
Balmanno K; Chell SD; Gillings AS; Hayat S; Cook SJ
Int J Cancer; 2009 Nov; 125(10):2332-41. PubMed ID: 19637312
[TBL] [Abstract][Full Text] [Related]
6. β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer.
Tenbaum SP; Ordóñez-Morán P; Puig I; Chicote I; Arqués O; Landolfi S; Fernández Y; Herance JR; Gispert JD; Mendizabal L; Aguilar S; Ramón y Cajal S; Schwartz S; Vivancos A; Espín E; Rojas S; Baselga J; Tabernero J; Muñoz A; Palmer HG
Nat Med; 2012 Jun; 18(6):892-901. PubMed ID: 22610277
[TBL] [Abstract][Full Text] [Related]
7. Basal and treatment-induced activation of AKT mediates resistance to cell death by AZD6244 (ARRY-142886) in Braf-mutant human cutaneous melanoma cells.
Gopal YN; Deng W; Woodman SE; Komurov K; Ram P; Smith PD; Davies MA
Cancer Res; 2010 Nov; 70(21):8736-47. PubMed ID: 20959481
[TBL] [Abstract][Full Text] [Related]
8. Regulation of the intracellular localization of Foxo3a by stress-activated protein kinase signaling pathways in skeletal muscle cells.
Clavel S; Siffroi-Fernandez S; Coldefy AS; Boulukos K; Pisani DF; Dérijard B
Mol Cell Biol; 2010 Jan; 30(2):470-80. PubMed ID: 19917721
[TBL] [Abstract][Full Text] [Related]
9. Activated phosphatidylinositol 3-kinase/Akt inhibits the transition of endothelial progenitor cells to mesenchymal cells by regulating the forkhead box subgroup O-3a signaling.
Zhang Z; Zhang T; Zhou Y; Wei X; Zhu J; Zhang J; Wang C
Cell Physiol Biochem; 2015; 35(4):1643-53. PubMed ID: 25824462
[TBL] [Abstract][Full Text] [Related]
10. Elucidating the role of the FoxO3a transcription factor in the IGF-1-induced migration and invasion of uveal melanoma cancer cells.
Yan F; Liao R; Farhan M; Wang T; Chen J; Wang Z; Little PJ; Zheng W
Biomed Pharmacother; 2016 Dec; 84():1538-1550. PubMed ID: 27881235
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of metadherin sensitizes breast cancer cells to AZD6244.
Kong X; Moran MS; Zhao Y; Yang Q
Cancer Biol Ther; 2012 Jan; 13(1):43-9. PubMed ID: 22336587
[TBL] [Abstract][Full Text] [Related]
12. Nuclear forkhead box O3a accumulation contributing to the proliferative suppression in liver cancer cells by PI3K/Akt signaling pathway.
Hou Y; Sun G; Jiang X; Zhu Z; Yang J
J Cancer Res Ther; 2018 Dec; 14(Supplement):S1124-S1128. PubMed ID: 30539857
[TBL] [Abstract][Full Text] [Related]
13. FOXO1 and FOXO3a sensitize non-small-cell lung cancer cells to cisplatin-induced apoptosis independent of Bim.
Sun T; Zhang J; Deng B; Fan X; Long T; Jin H; Tao S; Kang P; Tan Q
Acta Biochim Biophys Sin (Shanghai); 2020 Dec; 52(12):1348-1359. PubMed ID: 33167006
[TBL] [Abstract][Full Text] [Related]
14. Discontinuing MEK inhibitors in tumor cells with an acquired resistance increases migration and invasion.
Nörz D; Grottke A; Bach J; Herzberger C; Hofmann BT; Nashan B; Jücker M; Ewald F
Cell Signal; 2015 Nov; 27(11):2191-200. PubMed ID: 26210887
[TBL] [Abstract][Full Text] [Related]
15. Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer.
Qazi AK; Hussain A; Khan S; Aga MA; Behl A; Ali S; Singh SK; Taneja SC; Shah BA; Saxena AK; Mondhe DM; Hamid A
Cancer Lett; 2015 Apr; 359(1):47-56. PubMed ID: 25554016
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of phosphatidylinositol-3-kinase and mitogen-activated protein kinase kinase 1/2 prevents melanoma development and promotes melanoma regression in the transgenic TPRas mouse model.
Bedogni B; Welford SM; Kwan AC; Ranger-Moore J; Saboda K; Powell MB
Mol Cancer Ther; 2006 Dec; 5(12):3071-7. PubMed ID: 17172409
[TBL] [Abstract][Full Text] [Related]
17. FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity.
Sunayama J; Sato A; Matsuda K; Tachibana K; Watanabe E; Seino S; Suzuki K; Narita Y; Shibui S; Sakurada K; Kayama T; Tomiyama A; Kitanaka C
Stem Cells; 2011 Sep; 29(9):1327-37. PubMed ID: 21793107
[TBL] [Abstract][Full Text] [Related]
18. FOXO3a reactivation mediates the synergistic cytotoxic effects of rapamycin and cisplatin in oral squamous cell carcinoma cells.
Fang L; Wang H; Zhou L; Yu D
Toxicol Appl Pharmacol; 2011 Feb; 251(1):8-15. PubMed ID: 21092744
[TBL] [Abstract][Full Text] [Related]
19. Forkhead Box Transcription Factor (FOXO3a) mediates the cytotoxic effect of vernodalin in vitro and inhibits the breast tumor growth in vivo.
Ananda Sadagopan SK; Mohebali N; Looi CY; Hasanpourghadi M; Pandurangan AK; Arya A; Karimian H; Mustafa MR
J Exp Clin Cancer Res; 2015 Dec; 34():147. PubMed ID: 26643256
[TBL] [Abstract][Full Text] [Related]
20. Age-related differences in insulin-like growth factor-1 receptor signaling regulates Akt/FOXO3a and ERK/Fos pathways in vascular smooth muscle cells.
Li M; Chiu JF; Gagne J; Fukagawa NK
J Cell Physiol; 2008 Nov; 217(2):377-87. PubMed ID: 18615585
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
