These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

292 related articles for article (PubMed ID: 20484041)

  • 1. The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation.
    Zhao D; Zheng HQ; Zhou Z; Chen C
    Cancer Res; 2010 Jun; 70(11):4728-38. PubMed ID: 20484041
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs.
    Liu N; Li H; Li S; Shen M; Xiao N; Chen Y; Wang Y; Wang W; Wang R; Wang Q; Sun J; Wang P
    J Biol Chem; 2010 Jun; 285(24):18858-67. PubMed ID: 20388706
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TAZ antagonizes the WWP1-mediated KLF5 degradation and promotes breast cell proliferation and tumorigenesis.
    Zhao D; Zhi X; Zhou Z; Chen C
    Carcinogenesis; 2012 Jan; 33(1):59-67. PubMed ID: 22045023
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb.
    Kitagawa K; Hiramatsu Y; Uchida C; Isobe T; Hattori T; Oda T; Shibata K; Nakamura S; Kikuchi A; Kitagawa M
    Oncogene; 2009 Jun; 28(25):2393-405. PubMed ID: 19421138
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.
    Welcker M; Orian A; Jin J; Grim JE; Harper JW; Eisenman RN; Clurman BE
    Proc Natl Acad Sci U S A; 2004 Jun; 101(24):9085-90. PubMed ID: 15150404
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteasomal degradation of the KLF5 transcription factor through a ubiquitin-independent pathway.
    Chen C; Zhou Z; Guo P; Dong JT
    FEBS Lett; 2007 Mar; 581(6):1124-30. PubMed ID: 17320083
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis.
    Biswas M; Phan D; Watanabe M; Chan JY
    J Biol Chem; 2011 Nov; 286(45):39282-9. PubMed ID: 21953459
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PI3K-dependent phosphorylation of Fbw7 modulates substrate degradation and activity.
    Schülein C; Eilers M; Popov N
    FEBS Lett; 2011 Jul; 585(14):2151-7. PubMed ID: 21620836
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
    Inuzuka H; Shaik S; Onoyama I; Gao D; Tseng A; Maser RS; Zhai B; Wan L; Gutierrez A; Lau AW; Xiao Y; Christie AL; Aster J; Settleman J; Gygi SP; Kung AL; Look T; Nakayama KI; DePinho RA; Wei W
    Nature; 2011 Mar; 471(7336):104-9. PubMed ID: 21368833
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase.
    Isobe T; Hattori T; Kitagawa K; Uchida C; Kotake Y; Kosugi I; Oda T; Kitagawa M
    J Biol Chem; 2009 Oct; 284(41):27766-27779. PubMed ID: 19679664
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3beta/FBW7 loss of function.
    Rottmann S; Wang Y; Nasoff M; Deveraux QL; Quon KC
    Proc Natl Acad Sci U S A; 2005 Oct; 102(42):15195-200. PubMed ID: 16210249
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases.
    Hao B; Oehlmann S; Sowa ME; Harper JW; Pavletich NP
    Mol Cell; 2007 Apr; 26(1):131-43. PubMed ID: 17434132
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fbw7 isoform interaction contributes to cyclin E proteolysis.
    Zhang W; Koepp DM
    Mol Cancer Res; 2006 Dec; 4(12):935-43. PubMed ID: 17189384
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Triggering Fbw7-mediated proteasomal degradation of c-Myc by oridonin induces cell growth inhibition and apoptosis.
    Huang HL; Weng HY; Wang LQ; Yu CH; Huang QJ; Zhao PP; Wen JZ; Zhou H; Qu LH
    Mol Cancer Ther; 2012 May; 11(5):1155-65. PubMed ID: 22389469
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of the ubiquitin ligase Fbw7 in cancer progression.
    Cheng Y; Li G
    Cancer Metastasis Rev; 2012 Jun; 31(1-2):75-87. PubMed ID: 22124735
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Krüppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor binding protein 1.
    Zheng HQ; Zhou Z; Huang J; Chaudhury L; Dong JT; Chen C
    Oncogene; 2009 Oct; 28(42):3702-13. PubMed ID: 19668233
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thiazolidinediones modulate the expression of beta-catenin and other cell-cycle regulatory proteins by targeting the F-box proteins of Skp1-Cul1-F-box protein E3 ubiquitin ligase independently of peroxisome proliferator-activated receptor gamma.
    Wei S; Lin LF; Yang CC; Wang YC; Chang GD; Chen H; Chen CS
    Mol Pharmacol; 2007 Sep; 72(3):725-33. PubMed ID: 17569795
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human Kruppel-like factor 5 is a target of the E3 ubiquitin ligase WWP1 for proteolysis in epithelial cells.
    Chen C; Sun X; Guo P; Dong XY; Sethi P; Cheng X; Zhou J; Ling J; Simons JW; Lingrel JB; Dong JT
    J Biol Chem; 2005 Dec; 280(50):41553-61. PubMed ID: 16223724
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Negative regulation of HIF-1α by an FBW7-mediated degradation pathway during hypoxia.
    Cassavaugh JM; Hale SA; Wellman TL; Howe AK; Wong C; Lounsbury KM
    J Cell Biochem; 2011 Dec; 112(12):3882-90. PubMed ID: 21964756
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase.
    Wei W; Jin J; Schlisio S; Harper JW; Kaelin WG
    Cancer Cell; 2005 Jul; 8(1):25-33. PubMed ID: 16023596
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.