BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

262 related articles for article (PubMed ID: 20484410)

  • 1. cAMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4.
    Blancquaert S; Wang L; Paternot S; Coulonval K; Dumont JE; Harris TE; Roger PP
    Mol Endocrinol; 2010 Jul; 24(7):1453-68. PubMed ID: 20484410
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and stimulating type TSH receptor antibodies in the thyroid gland.
    Suh JM; Song JH; Kim DW; Kim H; Chung HK; Hwang JH; Kim JM; Hwang ES; Chung J; Han JH; Cho BY; Ro HK; Shong M
    J Biol Chem; 2003 Jun; 278(24):21960-71. PubMed ID: 12668683
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transforming growth factor beta(1) selectively inhibits the cyclic AMP-dependent proliferation of primary thyroid epithelial cells by preventing the association of cyclin D3-cdk4 with nuclear p27(kip1).
    Depoortere F; Pirson I; Bartek J; Dumont JE; Roger PP
    Mol Biol Cell; 2000 Mar; 11(3):1061-76. PubMed ID: 10712520
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A requirement for cyclin D3-cyclin-dependent kinase (cdk)-4 assembly in the cyclic adenosine monophosphate-dependent proliferation of thyrocytes.
    Depoortere F; Van Keymeulen A; Lukas J; Costagliola S; Bartkova J; Dumont JE; Bartek J; Roger PP; Dremier S
    J Cell Biol; 1998 Mar; 140(6):1427-39. PubMed ID: 9508775
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The cyclin D3-CDK4-p27kip1 holoenzyme in thyroid epithelial cells: activation by TSH, inhibition by TGFbeta, and phosphorylations of its subunits demonstrated by two-dimensional gel electrophoresis.
    Coulonval K; Bockstaele L; Paternot S; Dumont JE; Roger PP
    Exp Cell Res; 2003 Nov; 291(1):135-49. PubMed ID: 14597415
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential utilization of cyclin D1 and cyclin D3 in the distinct mitogenic stimulations by growth factors and TSH of human thyrocytes in primary culture.
    Paternot S; Dumont JE; Roger PP
    Mol Endocrinol; 2006 Dec; 20(12):3279-92. PubMed ID: 16916940
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cyclic AMP-dependent phosphorylation of cyclin D3-bound CDK4 determines the passage through the cell cycle restriction point in thyroid epithelial cells.
    Paternot S; Coulonval K; Dumont JE; Roger PP
    J Biol Chem; 2003 Jul; 278(29):26533-40. PubMed ID: 12730225
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cyclic AMP inhibits the proliferation of thyroid carcinoma cell lines through regulation of CDK4 phosphorylation.
    Rocha AS; Paternot S; Coulonval K; Dumont JE; Soares P; Roger PP
    Mol Biol Cell; 2008 Nov; 19(11):4814-25. PubMed ID: 18799615
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MTOR downregulates iodide uptake in thyrocytes.
    de Souza EC; Padrón AS; Braga WM; de Andrade BM; Vaisman M; Nasciutti LE; Ferreira AC; de Carvalho DP
    J Endocrinol; 2010 Jul; 206(1):113-20. PubMed ID: 20392814
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Luteinizing hormone stimulates mammalian target of rapamycin signaling in bovine luteal cells via pathways independent of AKT and mitogen-activated protein kinase: modulation of glycogen synthase kinase 3 and AMP-activated protein kinase.
    Hou X; Arvisais EW; Davis JS
    Endocrinology; 2010 Jun; 151(6):2846-57. PubMed ID: 20351317
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of AKT/mTORC1 signaling pathway.
    Palaniappan M; Menon KM
    Mol Endocrinol; 2010 Sep; 24(9):1782-93. PubMed ID: 20660299
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hydrogen peroxide impairs insulin-stimulated assembly of mTORC1.
    Zhang L; Kimball SR; Jefferson LS; Shenberger JS
    Free Radic Biol Med; 2009 Jun; 46(11):1500-9. PubMed ID: 19281842
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids.
    Mothe-Satney I; Gautier N; Hinault C; Lawrence JC; Van Obberghen E
    J Biol Chem; 2004 Oct; 279(41):42628-37. PubMed ID: 15292249
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Somatostatin interferes with thyrotropin-induced G1-S transition mediated by cAMP-dependent protein kinase and phosphatidylinositol 3-kinase. Involvement of RhoA and cyclin E x cyclin-dependent kinase 2 complexes.
    Medina DL; Toro MJ; Santisteban P
    J Biol Chem; 2000 May; 275(20):15549-56. PubMed ID: 10809788
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Distinct specificities of pRb phosphorylation by CDK4 activated by cyclin D1 or cyclin D3: differential involvement in the distinct mitogenic modes of thyroid epithelial cells.
    Paternot S; Arsenijevic T; Coulonval K; Bockstaele L; Dumont JE; Roger PP
    Cell Cycle; 2006 Jan; 5(1):61-70. PubMed ID: 16294008
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A.
    Tsygankova OM; Saavedra A; Rebhun JF; Quilliam LA; Meinkoth JL
    Mol Cell Biol; 2001 Mar; 21(6):1921-9. PubMed ID: 11238928
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glucagon represses signaling through the mammalian target of rapamycin in rat liver by activating AMP-activated protein kinase.
    Kimball SR; Siegfried BA; Jefferson LS
    J Biol Chem; 2004 Dec; 279(52):54103-9. PubMed ID: 15494402
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cyclic adenosine 3',5'-monophosphate (cAMP)-dependent protein kinases, but not exchange proteins directly activated by cAMP (Epac), mediate thyrotropin/cAMP-dependent regulation of thyroid cells.
    Dremier S; Milenkovic M; Blancquaert S; Dumont JE; Døskeland SO; Maenhaut C; Roger PP
    Endocrinology; 2007 Oct; 148(10):4612-22. PubMed ID: 17584967
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation.
    Suryawan A; Jeyapalan AS; Orellana RA; Wilson FA; Nguyen HV; Davis TA
    Am J Physiol Endocrinol Metab; 2008 Oct; 295(4):E868-75. PubMed ID: 18682538
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1.
    Oshiro N; Takahashi R; Yoshino K; Tanimura K; Nakashima A; Eguchi S; Miyamoto T; Hara K; Takehana K; Avruch J; Kikkawa U; Yonezawa K
    J Biol Chem; 2007 Jul; 282(28):20329-39. PubMed ID: 17517883
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.