BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 20486767)

  • 1. Stabilization of α-conotoxin AuIB: influences of disulfide connectivity and backbone cyclization.
    Lovelace ES; Gunasekera S; Alvarmo C; Clark RJ; Nevin ST; Grishin AA; Adams DJ; Craik DJ; Daly NL
    Antioxid Redox Signal; 2011 Jan; 14(1):87-95. PubMed ID: 20486767
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Improving the stability of α-conotoxin AuIB through N-to-C cyclization: the effect of linker length on stability and activity at nicotinic acetylcholine receptors.
    Armishaw CJ; Jensen AA; Balle LD; Scott KC; Sørensen L; Strømgaard K
    Antioxid Redox Signal; 2011 Jan; 14(1):65-76. PubMed ID: 20649464
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer.
    Wu X; Huang YH; Kaas Q; Harvey PJ; Wang CK; Tae HS; Adams DJ; Craik DJ
    J Biol Chem; 2017 Oct; 292(41):17101-17112. PubMed ID: 28851841
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alpha-conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of alpha3beta4 nicotinic acetylcholine receptors.
    Grishin AA; Wang CI; Muttenthaler M; Alewood PF; Lewis RJ; Adams DJ
    J Biol Chem; 2010 Jul; 285(29):22254-63. PubMed ID: 20466726
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB.
    Wu X; Tae HS; Huang YH; Adams DJ; Craik DJ; Kaas Q
    Biochem Pharmacol; 2018 Sep; 155():288-297. PubMed ID: 30009767
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activity.
    Dutton JL; Bansal PS; Hogg RC; Adams DJ; Alewood PF; Craik DJ
    J Biol Chem; 2002 Dec; 277(50):48849-57. PubMed ID: 12376538
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Establishing regiocontrol of disulfide bond isomers of alpha-conotoxin ImI via the synthesis of N-to-C cyclic analogs.
    Armishaw CJ; Dutton JL; Craik DJ; Alewood PF
    Biopolymers; 2010; 94(3):307-13. PubMed ID: 20013812
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Globular and ribbon isomers of Conus geographus α-conotoxins antagonize human nicotinic acetylcholine receptors.
    Tae HS; Gao B; Jin AH; Alewood PF; Adams DJ
    Biochem Pharmacol; 2021 Aug; 190():114638. PubMed ID: 34062129
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The chemical synthesis of α-conotoxins and structurally modified analogs with enhanced biological stability.
    Banerjee J; Gyanda R; Chang YP; Armishaw CJ
    Methods Mol Biol; 2013; 1081():13-34. PubMed ID: 24014431
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics.
    Jin AH; Brandstaetter H; Nevin ST; Tan CC; Clark RJ; Adams DJ; Alewood PF; Craik DJ; Daly NL
    BMC Struct Biol; 2007 Apr; 7():28. PubMed ID: 17445276
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA(B) receptor.
    Halai R; Callaghan B; Daly NL; Clark RJ; Adams DJ; Craik DJ
    J Med Chem; 2011 Oct; 54(19):6984-92. PubMed ID: 21888386
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure determination of the three disulfide bond isomers of alpha-conotoxin GI: a model for the role of disulfide bonds in structural stability.
    Gehrmann J; Alewood PF; Craik DJ
    J Mol Biol; 1998 May; 278(2):401-15. PubMed ID: 9571060
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function.
    Jin AH; Daly NL; Nevin ST; Wang CI; Dutertre S; Lewis RJ; Adams DJ; Craik DJ; Alewood PF
    J Med Chem; 2008 Sep; 51(18):5575-84. PubMed ID: 18754612
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and evaluation of disulfide-rich cyclic α-conotoxin [S9A]TxID analogues as novel α3β4 nAChR antagonists.
    Wang S; Ren J; Li R; Li X; Zhangsun D; Wu Y; Luo S
    Bioorg Chem; 2021 Jul; 112():104875. PubMed ID: 33823404
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of a new subclass of α-conotoxins in the venom of Conus australis.
    Lebbe EK; Peigneur S; Maiti M; Mille BG; Devi P; Ravichandran S; Lescrinier E; Waelkens E; D'Souza L; Herdewijn P; Tytgat J
    Toxicon; 2014 Dec; 91():145-54. PubMed ID: 25194747
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Influence of disulfide connectivity on structure and bioactivity of α-conotoxin TxIA.
    Wu Y; Wu X; Yu J; Zhu X; Zhangsun D; Luo S
    Molecules; 2014 Jan; 19(1):966-79. PubMed ID: 24434670
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclization of conotoxins to improve their biopharmaceutical properties.
    Clark RJ; Akcan M; Kaas Q; Daly NL; Craik DJ
    Toxicon; 2012 Mar; 59(4):446-55. PubMed ID: 21147143
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists.
    Muttenthaler M; Nevin ST; Grishin AA; Ngo ST; Choy PT; Daly NL; Hu SH; Armishaw CJ; Wang CI; Lewis RJ; Martin JL; Noakes PG; Craik DJ; Adams DJ; Alewood PF
    J Am Chem Soc; 2010 Mar; 132(10):3514-22. PubMed ID: 20163143
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rigidity of loop 1 contributes to equipotency of globular and ribbon isomers of α-conotoxin AusIA.
    Ho TNT; Abraham N; Lewis RJ
    Sci Rep; 2021 Nov; 11(1):21928. PubMed ID: 34753970
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of the Native Disulfide Isomers of the Novel χ-Conotoxin PnID: Implications for Further Increasing Conotoxin Diversity.
    Espiritu MJ; Taylor JK; Sugai CK; Thapa P; Loening NM; Gusman E; Baoanan ZG; Baumann MH; Bingham JP
    Mar Drugs; 2023 Jan; 21(2):. PubMed ID: 36827103
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.