These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 20486767)

  • 1. Stabilization of α-conotoxin AuIB: influences of disulfide connectivity and backbone cyclization.
    Lovelace ES; Gunasekera S; Alvarmo C; Clark RJ; Nevin ST; Grishin AA; Adams DJ; Craik DJ; Daly NL
    Antioxid Redox Signal; 2011 Jan; 14(1):87-95. PubMed ID: 20486767
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Improving the stability of α-conotoxin AuIB through N-to-C cyclization: the effect of linker length on stability and activity at nicotinic acetylcholine receptors.
    Armishaw CJ; Jensen AA; Balle LD; Scott KC; Sørensen L; Strømgaard K
    Antioxid Redox Signal; 2011 Jan; 14(1):65-76. PubMed ID: 20649464
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer.
    Wu X; Huang YH; Kaas Q; Harvey PJ; Wang CK; Tae HS; Adams DJ; Craik DJ
    J Biol Chem; 2017 Oct; 292(41):17101-17112. PubMed ID: 28851841
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alpha-conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of alpha3beta4 nicotinic acetylcholine receptors.
    Grishin AA; Wang CI; Muttenthaler M; Alewood PF; Lewis RJ; Adams DJ
    J Biol Chem; 2010 Jul; 285(29):22254-63. PubMed ID: 20466726
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB.
    Wu X; Tae HS; Huang YH; Adams DJ; Craik DJ; Kaas Q
    Biochem Pharmacol; 2018 Sep; 155():288-297. PubMed ID: 30009767
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A new level of conotoxin diversity, a non-native disulfide bond connectivity in alpha-conotoxin AuIB reduces structural definition but increases biological activity.
    Dutton JL; Bansal PS; Hogg RC; Adams DJ; Alewood PF; Craik DJ
    J Biol Chem; 2002 Dec; 277(50):48849-57. PubMed ID: 12376538
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Establishing regiocontrol of disulfide bond isomers of alpha-conotoxin ImI via the synthesis of N-to-C cyclic analogs.
    Armishaw CJ; Dutton JL; Craik DJ; Alewood PF
    Biopolymers; 2010; 94(3):307-13. PubMed ID: 20013812
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Globular and ribbon isomers of Conus geographus α-conotoxins antagonize human nicotinic acetylcholine receptors.
    Tae HS; Gao B; Jin AH; Alewood PF; Adams DJ
    Biochem Pharmacol; 2021 Aug; 190():114638. PubMed ID: 34062129
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The chemical synthesis of α-conotoxins and structurally modified analogs with enhanced biological stability.
    Banerjee J; Gyanda R; Chang YP; Armishaw CJ
    Methods Mol Biol; 2013; 1081():13-34. PubMed ID: 24014431
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics.
    Jin AH; Brandstaetter H; Nevin ST; Tan CC; Clark RJ; Adams DJ; Alewood PF; Craik DJ; Daly NL
    BMC Struct Biol; 2007 Apr; 7():28. PubMed ID: 17445276
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA(B) receptor.
    Halai R; Callaghan B; Daly NL; Clark RJ; Adams DJ; Craik DJ
    J Med Chem; 2011 Oct; 54(19):6984-92. PubMed ID: 21888386
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure determination of the three disulfide bond isomers of alpha-conotoxin GI: a model for the role of disulfide bonds in structural stability.
    Gehrmann J; Alewood PF; Craik DJ
    J Mol Biol; 1998 May; 278(2):401-15. PubMed ID: 9571060
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function.
    Jin AH; Daly NL; Nevin ST; Wang CI; Dutertre S; Lewis RJ; Adams DJ; Craik DJ; Alewood PF
    J Med Chem; 2008 Sep; 51(18):5575-84. PubMed ID: 18754612
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and evaluation of disulfide-rich cyclic α-conotoxin [S9A]TxID analogues as novel α3β4 nAChR antagonists.
    Wang S; Ren J; Li R; Li X; Zhangsun D; Wu Y; Luo S
    Bioorg Chem; 2021 Jul; 112():104875. PubMed ID: 33823404
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of a new subclass of α-conotoxins in the venom of Conus australis.
    Lebbe EK; Peigneur S; Maiti M; Mille BG; Devi P; Ravichandran S; Lescrinier E; Waelkens E; D'Souza L; Herdewijn P; Tytgat J
    Toxicon; 2014 Dec; 91():145-54. PubMed ID: 25194747
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Influence of disulfide connectivity on structure and bioactivity of α-conotoxin TxIA.
    Wu Y; Wu X; Yu J; Zhu X; Zhangsun D; Luo S
    Molecules; 2014 Jan; 19(1):966-79. PubMed ID: 24434670
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclization of conotoxins to improve their biopharmaceutical properties.
    Clark RJ; Akcan M; Kaas Q; Daly NL; Craik DJ
    Toxicon; 2012 Mar; 59(4):446-55. PubMed ID: 21147143
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists.
    Muttenthaler M; Nevin ST; Grishin AA; Ngo ST; Choy PT; Daly NL; Hu SH; Armishaw CJ; Wang CI; Lewis RJ; Martin JL; Noakes PG; Craik DJ; Adams DJ; Alewood PF
    J Am Chem Soc; 2010 Mar; 132(10):3514-22. PubMed ID: 20163143
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rigidity of loop 1 contributes to equipotency of globular and ribbon isomers of α-conotoxin AusIA.
    Ho TNT; Abraham N; Lewis RJ
    Sci Rep; 2021 Nov; 11(1):21928. PubMed ID: 34753970
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of the Native Disulfide Isomers of the Novel χ-Conotoxin PnID: Implications for Further Increasing Conotoxin Diversity.
    Espiritu MJ; Taylor JK; Sugai CK; Thapa P; Loening NM; Gusman E; Baoanan ZG; Baumann MH; Bingham JP
    Mar Drugs; 2023 Jan; 21(2):. PubMed ID: 36827103
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.