BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 20490796)

  • 1. Doxorubicin-induced suppression of poly(ADP-ribose) polymerase-1 (PARP-1) activity and expression and its implication for PARP inhibitors in clinical trials.
    Zaremba T; Thomas H; Cole M; Plummer ER; Curtin NJ
    Cancer Chemother Pharmacol; 2010 Sep; 66(4):807-12. PubMed ID: 20490796
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modeling pharmacodynamic response to the poly(ADP-Ribose) polymerase inhibitor ABT-888 in human peripheral blood mononuclear cells.
    Ji J; Kinders RJ; Zhang Y; Rubinstein L; Kummar S; Parchment RE; Tomaszewski JE; Doroshow JH
    PLoS One; 2011; 6(10):e26152. PubMed ID: 22028822
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Major contribution of the multidrug transporter P-glycoprotein to reduced susceptibility of poly(ADP-ribose) polymerase-1 knock-out cells to doxorubicin action.
    Wesierska-Gadek J
    J Cell Biochem; 2005 Aug; 95(5):1012-28. PubMed ID: 15861398
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of Kif4A in doxorubicin-induced apoptosis in breast cancer cells.
    Wang H; Lu C; Li Q; Xie J; Chen T; Tan Y; Wu C; Jiang J
    Mol Cells; 2014 Nov; 37(11):812-8. PubMed ID: 25377255
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of poly(ADP-ribose) polymerase contributes to development of doxorubicin-induced heart failure.
    Pacher P; Liaudet L; Bai P; Virag L; Mabley JG; Haskó G; Szabó C
    J Pharmacol Exp Ther; 2002 Mar; 300(3):862-7. PubMed ID: 11861791
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Poly(ADP-ribosyl)ation polymerases: mechanism and new target of anticancer therapy.
    Heitz F; Harter P; Ewald-Riegler N; Papsdorf M; Kommoss S; du Bois A
    Expert Rev Anticancer Ther; 2010 Jul; 10(7):1125-36. PubMed ID: 20645701
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression.
    Mariano G; Ricciardi MR; Trisciuoglio D; Zampieri M; Ciccarone F; Guastafierro T; Calabrese R; Valentini E; Tafuri A; Del Bufalo D; Caiafa P; Reale A
    Oncotarget; 2015 Jun; 6(17):15008-21. PubMed ID: 25938539
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Doxorubicin-induced testicular damage is related to PARP-1 signaling molecules in mice.
    Gungor-Ordueri NE; Kuscu N; Tasatargil A; Burgucu D; Karacan M; Celik-Ozenci C
    Pharmacol Rep; 2019 Aug; 71(4):591-602. PubMed ID: 31174020
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of poly(ADP-ribose) polymerase-1 or poly(ADP‑ribose) glycohydrolase individually, but not in combination, leads to improved chemotherapeutic efficacy in HeLa cells.
    Feng X; Koh DW
    Int J Oncol; 2013 Feb; 42(2):749-56. PubMed ID: 23254695
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Doxorubicin induces early embryo apoptosis by inhibiting poly(ADP ribose) polymerase.
    Wang QL; Sun SC; Han J; Kwak YC; Kim NH; Cui XS
    In Vivo; 2012; 26(5):827-34. PubMed ID: 22949597
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Beneficial effects of a novel ultrapotent poly(ADP-ribose) polymerase inhibitor in murine models of heart failure.
    Pacher P; Liaudet L; Mabley JG; Cziráki A; Haskó G; Szabó C
    Int J Mol Med; 2006 Feb; 17(2):369-75. PubMed ID: 16391839
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting poly(ADP-ribose) polymerase activity for cancer therapy.
    Mégnin-Chanet F; Bollet MA; Hall J
    Cell Mol Life Sci; 2010 Nov; 67(21):3649-62. PubMed ID: 20725763
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of hyperthermia and doxorubicin on nucleoid sedimentation and poly (ADP-ribose) polymerase activity in L1210 cells.
    Daugherty JP; Simpson TA; Mullins DW
    Cancer Chemother Pharmacol; 1988; 21(3):229-32. PubMed ID: 3129205
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A key role for poly(ADP-ribose) polymerase-1 activity during human dendritic cell maturation.
    Aldinucci A; Gerlini G; Fossati S; Cipriani G; Ballerini C; Biagioli T; Pimpinelli N; Borgognoni L; Massacesi L; Moroni F; Chiarugi A
    J Immunol; 2007 Jul; 179(1):305-12. PubMed ID: 17579050
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Immunohistochemical detection of poly(ADP-ribose) polymerase inhibition by ABT-888 in patients with refractory solid tumors and lymphomas.
    Yang SX; Kummar S; Steinberg SM; Murgo AJ; Gutierrez M; Rubinstein L; Nguyen D; Kaur G; Chen AP; Giranda VL; Tomaszewski JE; Doroshow JH;
    Cancer Biol Ther; 2009 Nov; 8(21):2004-9. PubMed ID: 19823047
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Platinated benzonaphthyridone is a stronger inhibitor of poly(ADP-ribose) polymerase-1 and a more potent anticancer agent than is the parent inhibitor.
    Wang B; Qian H; Yiu SM; Sun J; Zhu G
    Eur J Med Chem; 2014 Jan; 71():366-73. PubMed ID: 24361480
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers.
    Zaremba T; Thomas HD; Cole M; Coulthard SA; Plummer ER; Curtin NJ
    Biochem J; 2011 Jun; 436(3):671-9. PubMed ID: 21434873
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Poly(ADP-ribose) polymerase inhibitors in Ewing sarcoma.
    Vormoor B; Curtin NJ
    Curr Opin Oncol; 2014 Jul; 26(4):428-33. PubMed ID: 24840521
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Poly(ADP-ribose) polymerase-2 depletion reduces doxorubicin-induced damage through SIRT1 induction.
    Szántó M; Rutkai I; Hegedus C; Czikora Á; Rózsahegyi M; Kiss B; Virág L; Gergely P; Tóth A; Bai P
    Cardiovasc Res; 2011 Dec; 92(3):430-8. PubMed ID: 21921080
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics.
    He JX; Yang CH; Miao ZH
    Acta Pharmacol Sin; 2010 Sep; 31(9):1172-80. PubMed ID: 20676117
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.