BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

511 related articles for article (PubMed ID: 20494936)

  • 1. Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of HOXA genes in pediatric acute lymphoblastic leukemia.
    Schotte D; Lange-Turenhout EA; Stumpel DJ; Stam RW; Buijs-Gladdines JG; Meijerink JP; Pieters R; Den Boer ML
    Haematologica; 2010 Oct; 95(10):1675-82. PubMed ID: 20494936
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hypermethylation of specific microRNA genes in MLL-rearranged infant acute lymphoblastic leukemia: major matters at a micro scale.
    Stumpel DJ; Schotte D; Lange-Turenhout EA; Schneider P; Seslija L; de Menezes RX; Marquez VE; Pieters R; den Boer ML; Stam RW
    Leukemia; 2011 Mar; 25(3):429-39. PubMed ID: 21116279
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options.
    Stumpel DJ; Schneider P; van Roon EH; Boer JM; de Lorenzo P; Valsecchi MG; de Menezes RX; Pieters R; Stam RW
    Blood; 2009 Dec; 114(27):5490-8. PubMed ID: 19855078
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia.
    Schotte D; De Menezes RX; Akbari Moqadam F; Khankahdani LM; Lange-Turenhout E; Chen C; Pieters R; Den Boer ML
    Haematologica; 2011 May; 96(5):703-11. PubMed ID: 21242186
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization.
    Popovic R; Riesbeck LE; Velu CS; Chaubey A; Zhang J; Achille NJ; Erfurth FE; Eaton K; Lu J; Grimes HL; Chen J; Rowley JD; Zeleznik-Le NJ
    Blood; 2009 Apr; 113(14):3314-22. PubMed ID: 19188669
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Association of high-level MCL-1 expression with in vitro and in vivo prednisone resistance in MLL-rearranged infant acute lymphoblastic leukemia.
    Stam RW; Den Boer ML; Schneider P; de Boer J; Hagelstein J; Valsecchi MG; de Lorenzo P; Sallan SE; Brady HJ; Armstrong SA; Pieters R
    Blood; 2010 Feb; 115(5):1018-25. PubMed ID: 19965632
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis.
    Agraz-Doblas A; Bueno C; Bashford-Rogers R; Roy A; Schneider P; Bardini M; Ballerini P; Cazzaniga G; Moreno T; Revilla C; Gut M; Valsecchi MG; Roberts I; Pieters R; De Lorenzo P; Varela I; Menendez P; Stam RW
    Haematologica; 2019 Jun; 104(6):1176-1188. PubMed ID: 30679323
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of new microRNA genes and aberrant microRNA profiles in childhood acute lymphoblastic leukemia.
    Schotte D; Chau JC; Sylvester G; Liu G; Chen C; van der Velden VH; Broekhuis MJ; Peters TC; Pieters R; den Boer ML
    Leukemia; 2009 Feb; 23(2):313-22. PubMed ID: 18923441
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia.
    Jiang X; Huang H; Li Z; He C; Li Y; Chen P; Gurbuxani S; Arnovitz S; Hong GM; Price C; Ren H; Kunjamma RB; Neilly MB; Salat J; Wunderlich M; Slany RK; Zhang Y; Larson RA; Le Beau MM; Mulloy JC; Rowley JD; Chen J
    Proc Natl Acad Sci U S A; 2012 Nov; 109(47):19397-402. PubMed ID: 23132946
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Suppression of the let-7b microRNA pathway by DNA hypermethylation in infant acute lymphoblastic leukemia with MLL gene rearrangements.
    Nishi M; Eguchi-Ishimae M; Wu Z; Gao W; Iwabuki H; Kawakami S; Tauchi H; Inukai T; Sugita K; Hamasaki Y; Ishii E; Eguchi M
    Leukemia; 2013 Feb; 27(2):389-97. PubMed ID: 22918121
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MicroRNA-142-3p inhibits cell proliferation in human acute lymphoblastic leukemia by targeting the MLL-AF4 oncogene.
    Dou L; Li J; Zheng D; Li Y; Gao X; Xu C; Gao L; Wang L; Yu L
    Mol Biol Rep; 2013 Dec; 40(12):6811-9. PubMed ID: 24057258
    [TBL] [Abstract][Full Text] [Related]  

  • 12. miR-130b and miR-128a are essential lineage-specific codrivers of t(4;11) MLL-AF4 acute leukemia.
    Malouf C; Antunes ETB; O'Dwyer M; Jakobczyk H; Sahm F; Landua SL; Anderson RA; Soufi A; Halsey C; Ottersbach K
    Blood; 2021 Nov; 138(21):2066-2092. PubMed ID: 34111240
    [TBL] [Abstract][Full Text] [Related]  

  • 13. miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia.
    Li Z; Huang H; Chen P; He M; Li Y; Arnovitz S; Jiang X; He C; Hyjek E; Zhang J; Zhang Z; Elkahloun A; Cao D; Shen C; Wunderlich M; Wang Y; Neilly MB; Jin J; Wei M; Lu J; Valk PJM; Delwel R; Lowenberg B; Le Beau MM; Vardiman J; Mulloy JC; Zeleznik-Le NJ; Liu PP; Zhang J; Chen J
    Nat Commun; 2012 Feb; 3():688. PubMed ID: 22353710
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Methylation-mediated repression of microRNA-143 enhances MLL-AF4 oncogene expression.
    Dou L; Zheng D; Li J; Li Y; Gao L; Wang L; Yu L
    Oncogene; 2012 Jan; 31(4):507-17. PubMed ID: 21706045
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Silencing of the tumor suppressor gene FHIT is highly characteristic for MLL gene rearranged infant acute lymphoblastic leukemia.
    Stam RW; den Boer ML; Passier MM; Janka-Schaub GE; Sallan SE; Armstrong SA; Pieters R
    Leukemia; 2006 Feb; 20(2):264-71. PubMed ID: 16357833
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation.
    Orlovsky K; Kalinkovich A; Rozovskaia T; Shezen E; Itkin T; Alder H; Ozer HG; Carramusa L; Avigdor A; Volinia S; Buchberg A; Mazo A; Kollet O; Largman C; Croce CM; Nakamura T; Lapidot T; Canaani E
    Proc Natl Acad Sci U S A; 2011 May; 108(19):7956-61. PubMed ID: 21518888
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression of microRNA-181a and microRNA-196b in Egyptian Pediatric acute Lymphoblastic Leukemia.
    Shafik RE; Abd El Wahab N; Mokhtar MM; El Taweel MA; Ebeid E
    Asian Pac J Cancer Prev; 2020 Nov; 21(11):3429-3434. PubMed ID: 33247705
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Frequencies and prognostic impact of RAS mutations in MLL-rearranged acute lymphoblastic leukemia in infants.
    Driessen EM; van Roon EH; Spijkers-Hagelstein JA; Schneider P; de Lorenzo P; Valsecchi MG; Pieters R; Stam RW
    Haematologica; 2013 Jun; 98(6):937-44. PubMed ID: 23403319
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MicroRNA-155 is upregulated in MLL-rearranged AML but its absence does not affect leukemia development.
    Schneider E; Staffas A; Röhner L; Krowiorz K; Heuser M; Döhner K; Bullinger L; Döhner H; Fogelstrand L; Rouhi A; Kuchenbauer F; Palmqvist L
    Exp Hematol; 2016 Dec; 44(12):1166-1171. PubMed ID: 27619068
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation.
    Ferrando AA; Armstrong SA; Neuberg DS; Sallan SE; Silverman LB; Korsmeyer SJ; Look AT
    Blood; 2003 Jul; 102(1):262-8. PubMed ID: 12637319
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.