These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 20497909)

  • 1. Increased expression of the lysosomal cholesterol transporter NPC1 in Alzheimer's disease.
    Kågedal K; Kim WS; Appelqvist H; Chan S; Cheng D; Agholme L; Barnham K; McCann H; Halliday G; Garner B
    Biochim Biophys Acta; 2010 Aug; 1801(8):831-8. PubMed ID: 20497909
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alterations in gene expression in mutant amyloid precursor protein transgenic mice lacking Niemann-Pick type C1 protein.
    Maulik M; Thinakaran G; Kar S
    PLoS One; 2013; 8(1):e54605. PubMed ID: 23382922
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Loss of Cathepsin B and L Leads to Lysosomal Dysfunction, NPC-Like Cholesterol Sequestration and Accumulation of the Key Alzheimer's Proteins.
    Cermak S; Kosicek M; Mladenovic-Djordjevic A; Smiljanic K; Kanazir S; Hecimovic S
    PLoS One; 2016; 11(11):e0167428. PubMed ID: 27902765
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Altered levels and distribution of amyloid precursor protein and its processing enzymes in Niemann-Pick type C1-deficient mouse brains.
    Kodam A; Maulik M; Peake K; Amritraj A; Vetrivel KS; Thinakaran G; Vance JE; Kar S
    Glia; 2010 Aug; 58(11):1267-81. PubMed ID: 20607864
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutant human APP exacerbates pathology in a mouse model of NPC and its reversal by a β-cyclodextrin.
    Maulik M; Ghoshal B; Kim J; Wang Y; Yang J; Westaway D; Kar S
    Hum Mol Genet; 2012 Nov; 21(22):4857-75. PubMed ID: 22869680
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Increased ATP-binding cassette transporter A1 expression in Alzheimer's disease hippocampal neurons.
    Kim WS; Bhatia S; Elliott DA; Agholme L; Kågedal K; McCann H; Halliday GM; Barnham KJ; Garner B
    J Alzheimers Dis; 2010; 21(1):193-205. PubMed ID: 20413849
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mitochondrial cholesterol loading exacerbates amyloid beta peptide-induced inflammation and neurotoxicity.
    Fernández A; Llacuna L; Fernández-Checa JC; Colell A
    J Neurosci; 2009 May; 29(20):6394-405. PubMed ID: 19458211
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Presenilin Deficiency Results in Cellular Cholesterol Accumulation by Impairment of Protein Glycosylation and NPC1 Function.
    Fabiano M; Oikawa N; Kerksiek A; Furukawa JI; Yagi H; Kato K; Schweizer U; Annaert W; Kang J; Shen J; Lütjohann D; Walter J
    Int J Mol Sci; 2024 May; 25(10):. PubMed ID: 38791456
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cholesterol-depletion corrects APP and BACE1 misstrafficking in NPC1-deficient cells.
    Malnar M; Kosicek M; Lisica A; Posavec M; Krolo A; Njavro J; Omerbasic D; Tahirovic S; Hecimovic S
    Biochim Biophys Acta; 2012 Aug; 1822(8):1270-83. PubMed ID: 22551668
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP + PS1 transgenic mouse brains.
    Amritraj A; Hawkes C; Phinney AL; Mount HT; Scott CD; Westaway D; Kar S
    Neurobiol Aging; 2009 Jan; 30(1):54-70. PubMed ID: 17561313
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacological activation of LXRs decreases amyloid-β levels in Niemann-Pick type C model cells.
    Stefulj J; Peric M; Malnar M; Kosicek M; Schweinzer C; Zivkovic J; Scholler M; Panzenboeck U; Hecimovic S
    Curr Pharm Biotechnol; 2013; 14(6):582-93. PubMed ID: 24016269
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cholesterol accumulation in Niemann Pick type C (NPC) model cells causes a shift in APP localization to lipid rafts.
    Kosicek M; Malnar M; Goate A; Hecimovic S
    Biochem Biophys Res Commun; 2010 Mar; 393(3):404-9. PubMed ID: 20138836
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cholesterol-dependent energy transfer between fluorescent proteins-insights into protein proximity of APP and BACE1 in different membranes in Niemann-Pick type C disease cells.
    von Einem B; Weber P; Wagner M; Malnar M; Kosicek M; Hecimovic S; Arnim CA; Schneckenburger H
    Int J Mol Sci; 2012 Nov; 13(12):15801-12. PubMed ID: 23443094
    [TBL] [Abstract][Full Text] [Related]  

  • 14. BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains.
    Causevic M; Dominko K; Malnar M; Vidatic L; Cermak S; Pigoni M; Kuhn PH; Colombo A; Havas D; Flunkert S; McDonald J; Gunnersen JM; Hutter-Paier B; Tahirovic S; Windisch M; Krainc D; Lichtenthaler SF; Hecimovic S
    PLoS One; 2018; 13(7):e0200344. PubMed ID: 29979789
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Presenilin-1 but not amyloid precursor protein mutations present in mouse models of Alzheimer's disease attenuate the response of cultured cells to γ-secretase modulators regardless of their potency and structure.
    Hahn S; Brüning T; Ness J; Czirr E; Baches S; Gijsen H; Korth C; Pietrzik CU; Bulic B; Weggen S
    J Neurochem; 2011 Feb; 116(3):385-95. PubMed ID: 21091478
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lysosomal vitamin E accumulation in Niemann-Pick type C disease.
    Yévenes LF; Klein A; Castro JF; Marín T; Leal N; Leighton F; Alvarez AR; Zanlungo S
    Biochim Biophys Acta; 2012 Feb; 1822(2):150-60. PubMed ID: 22120593
    [TBL] [Abstract][Full Text] [Related]  

  • 17. STARD1 and NPC1 expression as pathological markers associated with astrogliosis in post-mortem brains from patients with Alzheimer's disease and Down syndrome.
    Arenas F; Castro F; Nuñez S; Gay G; Garcia-Ruiz C; Fernandez-Checa JC
    Aging (Albany NY); 2020 Jan; 12(1):571-592. PubMed ID: 31902793
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alternations of central insulin-like growth factor-1 sensitivity in APP/PS1 transgenic mice and neuronal models.
    Zhang B; Tang XC; Zhang HY
    J Neurosci Res; 2013 May; 91(5):717-25. PubMed ID: 23401344
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Effects of Extracellular Serum Concentration on APP Processing in Npc1-Deficient APP-Overexpressing N2a Cells.
    Maulik M; Vergote D; Phukan G; Chung J; Thinakaran G; Kar S
    Mol Neurobiol; 2018 Jul; 55(7):5757-5766. PubMed ID: 29052144
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alterations in brain cholesterol metabolism in the APPSLxPS1mut mouse, a model for Alzheimer's disease.
    Vanmierlo T; Bloks VW; van Vark-van der Zee LC; Rutten K; Kerksiek A; Friedrichs S; Sijbrands E; Steinbusch HW; Kuipers F; Lütjohann D; Mulder M
    J Alzheimers Dis; 2010; 19(1):117-27. PubMed ID: 20061631
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.