220 related articles for article (PubMed ID: 20498635)
1. Proton-assisted amino-acid transporters are conserved regulators of proliferation and amino-acid-dependent mTORC1 activation.
Heublein S; Kazi S; Ogmundsdóttir MH; Attwood EV; Kala S; Boyd CA; Wilson C; Goberdhan DC
Oncogene; 2010 Jul; 29(28):4068-79. PubMed ID: 20498635
[TBL] [Abstract][Full Text] [Related]
2. Proton-assisted amino acid transporter PAT1 complexes with Rag GTPases and activates TORC1 on late endosomal and lysosomal membranes.
Ögmundsdóttir MH; Heublein S; Kazi S; Reynolds B; Visvalingam SM; Shaw MK; Goberdhan DC
PLoS One; 2012; 7(5):e36616. PubMed ID: 22574197
[TBL] [Abstract][Full Text] [Related]
3. PAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancer.
Fan SJ; Snell C; Turley H; Li JL; McCormick R; Perera SM; Heublein S; Kazi S; Azad A; Wilson C; Harris AL; Goberdhan DC
Oncogene; 2016 Jun; 35(23):3004-15. PubMed ID: 26434594
[TBL] [Abstract][Full Text] [Related]
4. Intracellular amino acid sensing and mTORC1-regulated growth: new ways to block an old target?
Goberdhan DC
Curr Opin Investig Drugs; 2010 Dec; 11(12):1360-7. PubMed ID: 21154118
[TBL] [Abstract][Full Text] [Related]
5. Abundance of amino acid transporters involved in mTORC1 activation in skeletal muscle of neonatal pigs is developmentally regulated.
Suryawan A; Nguyen HV; Almonaci RD; Davis TA
Amino Acids; 2013 Sep; 45(3):523-30. PubMed ID: 22643846
[TBL] [Abstract][Full Text] [Related]
6. PAT-related amino acid transporters regulate growth via a novel mechanism that does not require bulk transport of amino acids.
Goberdhan DC; Meredith D; Boyd CA; Wilson C
Development; 2005 May; 132(10):2365-75. PubMed ID: 15843412
[TBL] [Abstract][Full Text] [Related]
7. Dennd3 functions as a guanine nucleotide exchange factor for small GTPase Rab12 in mouse embryonic fibroblasts.
Matsui T; Noguchi K; Fukuda M
J Biol Chem; 2014 May; 289(20):13986-95. PubMed ID: 24719330
[TBL] [Abstract][Full Text] [Related]
8. Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4.
Matsui T; Fukuda M
EMBO Rep; 2013 May; 14(5):450-7. PubMed ID: 23478338
[TBL] [Abstract][Full Text] [Related]
9. Amino acid regulation of TOR complex 1.
Avruch J; Long X; Ortiz-Vega S; Rapley J; Papageorgiou A; Dai N
Am J Physiol Endocrinol Metab; 2009 Apr; 296(4):E592-602. PubMed ID: 18765678
[TBL] [Abstract][Full Text] [Related]
10. Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the Spot.
Goberdhan DC; Wilson C; Harris AL
Cell Metab; 2016 Apr; 23(4):580-9. PubMed ID: 27076075
[TBL] [Abstract][Full Text] [Related]
11. The emerging role of mTORC1 signaling in placental nutrient-sensing.
Jansson T; Aye IL; Goberdhan DC
Placenta; 2012 Nov; 33 Suppl 2(Suppl 2):e23-9. PubMed ID: 22687819
[TBL] [Abstract][Full Text] [Related]
12. Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma.
Park YY; Sohn BH; Johnson RL; Kang MH; Kim SB; Shim JJ; Mangala LS; Kim JH; Yoo JE; Rodriguez-Aguayo C; Pradeep S; Hwang JE; Jang HJ; Lee HS; Rupaimoole R; Lopez-Berestein G; Jeong W; Park IS; Park YN; Sood AK; Mills GB; Lee JS
Hepatology; 2016 Jan; 63(1):159-72. PubMed ID: 26389641
[TBL] [Abstract][Full Text] [Related]
13. Amino Acid Transporters Are a Vital Focal Point in the Control of mTORC1 Signaling and Cancer.
Cormerais Y; Vučetić M; Parks SK; Pouyssegur J
Int J Mol Sci; 2020 Dec; 22(1):. PubMed ID: 33375025
[TBL] [Abstract][Full Text] [Related]
14. The amino acid transporter PAT1 regulates mTORC1 in a nutrient-sensitive manner that requires its transport activity.
Zhao L; Zhang X; Ji X; Jin Y; Liu W
Cell Signal; 2019 Jan; 53():59-67. PubMed ID: 30253187
[TBL] [Abstract][Full Text] [Related]
15. PATs and SNATs: Amino Acid Sensors in Disguise.
Fan SJ; Goberdhan DCI
Front Pharmacol; 2018; 9():640. PubMed ID: 29971004
[TBL] [Abstract][Full Text] [Related]
16. Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling.
Wang X; Fonseca BD; Tang H; Liu R; Elia A; Clemens MJ; Bommer UA; Proud CG
J Biol Chem; 2008 Nov; 283(45):30482-92. PubMed ID: 18676370
[TBL] [Abstract][Full Text] [Related]
17. SLC38A9: A lysosomal amino acid transporter at the core of the amino acid-sensing machinery that controls MTORC1.
Rebsamen M; Superti-Furga G
Autophagy; 2016 Jun; 12(6):1061-2. PubMed ID: 26431368
[TBL] [Abstract][Full Text] [Related]
18. mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient.
Wyant GA; Abu-Remaileh M; Wolfson RL; Chen WW; Freinkman E; Danai LV; Vander Heiden MG; Sabatini DM
Cell; 2017 Oct; 171(3):642-654.e12. PubMed ID: 29053970
[TBL] [Abstract][Full Text] [Related]
19. mTORC1 signaling can regulate growth factor activation of p44/42 mitogen-activated protein kinases through protein phosphatase 2A.
Harwood FC; Shu L; Houghton PJ
J Biol Chem; 2008 Feb; 283(5):2575-85. PubMed ID: 18056704
[TBL] [Abstract][Full Text] [Related]
20. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.
Feldman ME; Apsel B; Uotila A; Loewith R; Knight ZA; Ruggero D; Shokat KM
PLoS Biol; 2009 Feb; 7(2):e38. PubMed ID: 19209957
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
