153 related articles for article (PubMed ID: 20502009)
1. A novel mode of action of the putative sphingosine kinase inhibitor 2-(p-hydroxyanilino)-4-(p-chlorophenyl) thiazole (SKI II): induction of lysosomal sphingosine kinase 1 degradation.
Ren S; Xin C; Pfeilschifter J; Huwiler A
Cell Physiol Biochem; 2010; 26(1):97-104. PubMed ID: 20502009
[TBL] [Abstract][Full Text] [Related]
2. The sphingosine kinase inhibitor 2-(p-hyroxyanilino)-4-(p-chlorophenyl)thiazole reduces androgen receptor expression via an oxidative stress-dependent mechanism.
Tonelli F; Alossaimi M; Williamson L; Tate RJ; Watson DG; Chan E; Bittman R; Pyne NJ; Pyne S
Br J Pharmacol; 2013 Mar; 168(6):1497-505. PubMed ID: 23113536
[TBL] [Abstract][Full Text] [Related]
3. Activation of sphingosine kinase-1 mediates induction of endothelial cell proliferation and angiogenesis by epoxyeicosatrienoic acids.
Yan G; Chen S; You B; Sun J
Cardiovasc Res; 2008 May; 78(2):308-14. PubMed ID: 18192241
[TBL] [Abstract][Full Text] [Related]
4. Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells.
McNaughton M; Pitman M; Pitson SM; Pyne NJ; Pyne S
Oncotarget; 2016 Mar; 7(13):16663-75. PubMed ID: 26934645
[TBL] [Abstract][Full Text] [Related]
5. Histamine increases sphingosine kinase-1 expression and activity in the human arterial endothelial cell line EA.hy 926 by a PKC-alpha-dependent mechanism.
Huwiler A; Döll F; Ren S; Klawitter S; Greening A; Römer I; Bubnova S; Reinsberg L; Pfeilschifter J
Biochim Biophys Acta; 2006 Mar; 1761(3):367-76. PubMed ID: 16571380
[TBL] [Abstract][Full Text] [Related]
6. The sphingosine kinase 1 inhibitor 2-(p-hydroxyanilino)-4-(p-chlorophenyl)thiazole induces proteasomal degradation of sphingosine kinase 1 in mammalian cells.
Loveridge C; Tonelli F; Leclercq T; Lim KG; Long JS; Berdyshev E; Tate RJ; Natarajan V; Pitson SM; Pyne NJ; Pyne S
J Biol Chem; 2010 Dec; 285(50):38841-52. PubMed ID: 20926375
[TBL] [Abstract][Full Text] [Related]
7. Short Periods of Hypoxia Upregulate Sphingosine Kinase 1 and Increase Vasodilation of Arteries to Sphingosine 1-Phosphate (S1P) via S1P
Alganga H; Almabrouk TAM; Katwan OJ; Daly CJ; Pyne S; Pyne NJ; Kennedy S
J Pharmacol Exp Ther; 2019 Oct; 371(1):63-74. PubMed ID: 31371480
[TBL] [Abstract][Full Text] [Related]
8. Increased sphingosine 1-phosphate mediates inflammation and fibrosis in tubular injury in diabetic nephropathy.
Yaghobian D; Don AS; Yaghobian S; Chen X; Pollock CA; Saad S
Clin Exp Pharmacol Physiol; 2016 Jan; 43(1):56-66. PubMed ID: 26414003
[TBL] [Abstract][Full Text] [Related]
9. From Sphingosine Kinase to Dihydroceramide Desaturase: A Structure-Activity Relationship (SAR) Study of the Enzyme Inhibitory and Anticancer Activity of 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol (SKI-II).
Aurelio L; Scullino CV; Pitman MR; Sexton A; Oliver V; Davies L; Rebello RJ; Furic L; Creek DJ; Pitson SM; Flynn BL
J Med Chem; 2016 Feb; 59(3):965-84. PubMed ID: 26780304
[TBL] [Abstract][Full Text] [Related]
10. Inhibition kinetics and regulation of sphingosine kinase 1 expression in prostate cancer cells: functional differences between sphingosine kinase 1a and 1b.
Lim KG; Tonelli F; Berdyshev E; Gorshkova I; Leclercq T; Pitson SM; Bittman R; Pyne S; Pyne NJ
Int J Biochem Cell Biol; 2012 Sep; 44(9):1457-64. PubMed ID: 22634604
[TBL] [Abstract][Full Text] [Related]
11. The roles of sphingosine kinases 1 and 2 in regulating the Warburg effect in prostate cancer cells.
Watson DG; Tonelli F; Alossaimi M; Williamson L; Chan E; Gorshkova I; Berdyshev E; Bittman R; Pyne NJ; Pyne S
Cell Signal; 2013 Apr; 25(4):1011-7. PubMed ID: 23314175
[TBL] [Abstract][Full Text] [Related]
12. Sphingosine kinase regulates voltage operated calcium channels in GH4C1 rat pituitary cells.
Blom T; Bergelin N; Slotte JP; Törnquist K
Cell Signal; 2006 Sep; 18(9):1366-75. PubMed ID: 16321506
[TBL] [Abstract][Full Text] [Related]
13. Antitumor activity of sphingosine kinase inhibitors.
French KJ; Upson JJ; Keller SN; Zhuang Y; Yun JK; Smith CD
J Pharmacol Exp Ther; 2006 Aug; 318(2):596-603. PubMed ID: 16632640
[TBL] [Abstract][Full Text] [Related]
14. Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53.
Taha TA; Osta W; Kozhaya L; Bielawski J; Johnson KR; Gillanders WE; Dbaibo GS; Hannun YA; Obeid LM
J Biol Chem; 2004 May; 279(19):20546-54. PubMed ID: 14988393
[TBL] [Abstract][Full Text] [Related]
15. Activation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimers.
Mercado N; Kizawa Y; Ueda K; Xiong Y; Kimura G; Moses A; Curtis JM; Ito K; Barnes PJ
PLoS One; 2014; 9(2):e88168. PubMed ID: 24505412
[TBL] [Abstract][Full Text] [Related]
16. The epidermal growth factor stimulates sphingosine kinase-1 expression and activity in the human mammary carcinoma cell line MCF7.
Döll F; Pfeilschifter J; Huwiler A
Biochim Biophys Acta; 2005 Dec; 1738(1-3):72-81. PubMed ID: 16414307
[TBL] [Abstract][Full Text] [Related]
17. SphK1 inhibitor SKI II inhibits the proliferation of human hepatoma HepG2 cells via the Wnt5A/β-catenin signaling pathway.
Liu H; Zhang CX; Ma Y; He HW; Wang JP; Shao RG
Life Sci; 2016 Apr; 151():23-29. PubMed ID: 26944438
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of dihydroceramide desaturase activity by the sphingosine kinase inhibitor SKI II.
Cingolani F; Casasampere M; Sanllehí P; Casas J; Bujons J; Fabrias G
J Lipid Res; 2014 Aug; 55(8):1711-20. PubMed ID: 24875537
[TBL] [Abstract][Full Text] [Related]
19. Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression.
Ren S; Babelova A; Moreth K; Xin C; Eberhardt W; Doller A; Pavenstädt H; Schaefer L; Pfeilschifter J; Huwiler A
Kidney Int; 2009 Oct; 76(8):857-67. PubMed ID: 19657322
[TBL] [Abstract][Full Text] [Related]
20. Sphingolipids and the sphingosine kinase inhibitor, SKI II, induce BCL-2-independent apoptosis in human prostatic adenocarcinoma cells.
Leroux ME; Auzenne E; Evans R; Hail N; Spohn W; Ghosh SC; Farquhar D; McDonnell T; Klostergaard J
Prostate; 2007 Nov; 67(15):1699-717. PubMed ID: 17879964
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
