349 related articles for article (PubMed ID: 20502642)
21. Excessive hydrogen peroxide enhances the attachment of amyloid β1-42 in the lens epithelium of UPL rats, a hereditary model for cataracts.
Nagai N; Ito Y
Toxicology; 2014 Jan; 315():55-64. PubMed ID: 23941810
[TBL] [Abstract][Full Text] [Related]
22. The AMY antigen co-occurs with abeta and follows its deposition in the amyloid plaques of Alzheimer's disease and down syndrome.
Lemere CA; Grenfell TJ; Selkoe DJ
Am J Pathol; 1999 Jul; 155(1):29-37. PubMed ID: 10393833
[TBL] [Abstract][Full Text] [Related]
23. Alzheimer's-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition.
Jiang Y; Mullaney KA; Peterhoff CM; Che S; Schmidt SD; Boyer-Boiteau A; Ginsberg SD; Cataldo AM; Mathews PM; Nixon RA
Proc Natl Acad Sci U S A; 2010 Jan; 107(4):1630-5. PubMed ID: 20080541
[TBL] [Abstract][Full Text] [Related]
24. Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome.
Cenini G; Dowling AL; Beckett TL; Barone E; Mancuso C; Murphy MP; Levine H; Lott IT; Schmitt FA; Butterfield DA; Head E
Biochim Biophys Acta; 2012 Feb; 1822(2):130-8. PubMed ID: 22009041
[TBL] [Abstract][Full Text] [Related]
25. Down syndrome individuals with Alzheimer's disease have a distinct neuroinflammatory phenotype compared to sporadic Alzheimer's disease.
Wilcock DM; Hurban J; Helman AM; Sudduth TL; McCarty KL; Beckett TL; Ferrell JC; Murphy MP; Abner EL; Schmitt FA; Head E
Neurobiol Aging; 2015 Sep; 36(9):2468-74. PubMed ID: 26103884
[TBL] [Abstract][Full Text] [Related]
26. BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice.
Kim W; Ma L; Lomoio S; Willen R; Lombardo S; Dong J; Haydon PG; Tesco G
Mol Neurodegener; 2018 Feb; 13(1):6. PubMed ID: 29391027
[TBL] [Abstract][Full Text] [Related]
27. Sequence of deposition of heterogeneous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation.
Lemere CA; Blusztajn JK; Yamaguchi H; Wisniewski T; Saido TC; Selkoe DJ
Neurobiol Dis; 1996 Feb; 3(1):16-32. PubMed ID: 9173910
[TBL] [Abstract][Full Text] [Related]
28. ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.
Sakae N; Liu CC; Shinohara M; Frisch-Daiello J; Ma L; Yamazaki Y; Tachibana M; Younkin L; Kurti A; Carrasquillo MM; Zou F; Sevlever D; Bisceglio G; Gan M; Fol R; Knight P; Wang M; Han X; Fryer JD; Fitzgerald ML; Ohyagi Y; Younkin SG; Bu G; Kanekiyo T
J Neurosci; 2016 Mar; 36(13):3848-59. PubMed ID: 27030769
[TBL] [Abstract][Full Text] [Related]
29. Human Brain-Derived Aβ Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP.
Wang Z; Jackson RJ; Hong W; Taylor WM; Corbett GT; Moreno A; Liu W; Li S; Frosch MP; Slutsky I; Young-Pearse TL; Spires-Jones TL; Walsh DM
J Neurosci; 2017 Dec; 37(49):11947-11966. PubMed ID: 29101243
[TBL] [Abstract][Full Text] [Related]
30. A fibril-specific, conformation-dependent antibody recognizes a subset of Abeta plaques in Alzheimer disease, Down syndrome and Tg2576 transgenic mouse brain.
Sarsoza F; Saing T; Kayed R; Dahlin R; Dick M; Broadwater-Hollifield C; Mobley S; Lott I; Doran E; Gillen D; Anderson-Bergman C; Cribbs DH; Glabe C; Head E
Acta Neuropathol; 2009 Oct; 118(4):505-17. PubMed ID: 19360426
[TBL] [Abstract][Full Text] [Related]
31. Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain.
Di Domenico F; Coccia R; Cocciolo A; Murphy MP; Cenini G; Head E; Butterfield DA; Giorgi A; Schinina ME; Mancuso C; Cini C; Perluigi M
Biochim Biophys Acta; 2013 Aug; 1832(8):1249-59. PubMed ID: 23603808
[TBL] [Abstract][Full Text] [Related]
32. Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain.
Perluigi M; Pupo G; Tramutola A; Cini C; Coccia R; Barone E; Head E; Butterfield DA; Di Domenico F
Biochim Biophys Acta; 2014 Jul; 1842(7):1144-53. PubMed ID: 24735980
[TBL] [Abstract][Full Text] [Related]
33. Elevated soluble amyloid beta protofibrils in Down syndrome and Alzheimer's disease.
Johannesson M; Sahlin C; Söderberg L; Basun H; Fälting J; Möller C; Zachrisson O; Sunnemark D; Svensson A; Odergren T; Lannfelt L
Mol Cell Neurosci; 2021 Jul; 114():103641. PubMed ID: 34091073
[TBL] [Abstract][Full Text] [Related]
34. Brain amyloid-β oligomers in ageing and Alzheimer's disease.
Lesné SE; Sherman MA; Grant M; Kuskowski M; Schneider JA; Bennett DA; Ashe KH
Brain; 2013 May; 136(Pt 5):1383-98. PubMed ID: 23576130
[TBL] [Abstract][Full Text] [Related]
35. Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome.
Teller JK; Russo C; DeBusk LM; Angelini G; Zaccheo D; Dagna-Bricarelli F; Scartezzini P; Bertolini S; Mann DM; Tabaton M; Gambetti P
Nat Med; 1996 Jan; 2(1):93-5. PubMed ID: 8564851
[TBL] [Abstract][Full Text] [Related]
36. Aging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology.
Head E; Lott IT; Wilcock DM; Lemere CA
Curr Alzheimer Res; 2016; 13(1):18-29. PubMed ID: 26651341
[TBL] [Abstract][Full Text] [Related]
37. The amyloid plaque proteome in early onset Alzheimer's disease and Down syndrome.
Drummond E; Kavanagh T; Pires G; Marta-Ariza M; Kanshin E; Nayak S; Faustin A; Berdah V; Ueberheide B; Wisniewski T
Acta Neuropathol Commun; 2022 Apr; 10(1):53. PubMed ID: 35418158
[TBL] [Abstract][Full Text] [Related]
38. App gene dosage modulates endosomal abnormalities of Alzheimer's disease in a segmental trisomy 16 mouse model of down syndrome.
Cataldo AM; Petanceska S; Peterhoff CM; Terio NB; Epstein CJ; Villar A; Carlson EJ; Staufenbiel M; Nixon RA
J Neurosci; 2003 Jul; 23(17):6788-92. PubMed ID: 12890772
[TBL] [Abstract][Full Text] [Related]
39. USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and Aβ generation.
Zheng Q; Song B; Li G; Cai F; Wu M; Zhao Y; Jiang L; Guo T; Shen M; Hou H; Zhou Y; Zhao Y; Di A; Zhang L; Zeng F; Zhang XF; Luo H; Zhang X; Zhang H; Zeng Z; Huang TY; Dong C; Qing H; Zhang Y; Zhang Q; Wang X; Wu Y; Xu H; Song W; Wang X
J Clin Invest; 2022 Mar; 132(5):. PubMed ID: 35229730
[TBL] [Abstract][Full Text] [Related]
40. Characterization of Abeta11-40/42 peptide deposition in Alzheimer's disease and young Down's syndrome brains: implication of N-terminally truncated Abeta species in the pathogenesis of Alzheimer's disease.
Liu K; Solano I; Mann D; Lemere C; Mercken M; Trojanowski JQ; Lee VM
Acta Neuropathol; 2006 Aug; 112(2):163-74. PubMed ID: 16865398
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
