These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
141 related articles for article (PubMed ID: 20503979)
61. From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold. Rampa A; Mancini F; De Simone A; Falchi F; Belluti F; Di Martino RM; Gobbi S; Andrisano V; Tarozzi A; Bartolini M; Cavalli A; Bisi A Bioorg Med Chem Lett; 2015 Jul; 25(14):2804-8. PubMed ID: 26003339 [TBL] [Abstract][Full Text] [Related]
62. New tetromycin derivatives with anti-trypanosomal and protease inhibitory activities. Pimentel-Elardo SM; Buback V; Gulder TAM; Bugni TS; Reppart J; Bringmann G; Ireland CM; Schirmeister T; Hentschel U Mar Drugs; 2011; 9(10):1682-1697. PubMed ID: 22072992 [TBL] [Abstract][Full Text] [Related]
64. Halichondramine, a new tetracyclic bipiperidine alkaloid from the marine sponge Halichondria sp. Chill L; Yosief T; Kashman Y J Nat Prod; 2002 Nov; 65(11):1738-41. PubMed ID: 12444719 [TBL] [Abstract][Full Text] [Related]
65. Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitors. Brodney MA; Beck EM; Butler CR; Barreiro G; Johnson EF; Riddell D; Parris K; Nolan CE; Fan Y; Atchison K; Gonzales C; Robshaw AE; Doran SD; Bundesmann MW; Buzon L; Dutra J; Henegar K; LaChapelle E; Hou X; Rogers BN; Pandit J; Lira R; Martinez-Alsina L; Mikochik P; Murray JC; Ogilvie K; Price L; Sakya SM; Yu A; Zhang Y; O'Neill BT J Med Chem; 2015 Apr; 58(7):3223-52. PubMed ID: 25781223 [TBL] [Abstract][Full Text] [Related]
66. Small-molecule BACE1 inhibitors: a patent literature review (2006 - 2011). Probst G; Xu YZ Expert Opin Ther Pat; 2012 May; 22(5):511-40. PubMed ID: 22512789 [TBL] [Abstract][Full Text] [Related]
67. Balancing potency and basicity by incorporating fluoropyridine moieties: Discovery of a 1-amino-3,4-dihydro-2,6-naphthyridine BACE1 inhibitor that affords robust and sustained central Aβ reduction. Nakahara K; Mitsuoka Y; Kasuya S; Yamamoto T; Yamamoto S; Ito H; Kido Y; Kusakabe KI Eur J Med Chem; 2021 Apr; 216():113270. PubMed ID: 33765486 [TBL] [Abstract][Full Text] [Related]
68. From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects. Pont C; Ginex T; Griñán-Ferré C; Scheiner M; Mattellone A; Martínez N; Arce EM; Soriano-Fernández Y; Naldi M; De Simone A; Barenys M; Gómez-Catalán J; Pérez B; Sabate R; Andrisano V; Loza MI; Brea J; Bartolini M; Bolognesi ML; Decker M; Pallàs M; Luque FJ; Muñoz-Torrero D Eur J Med Chem; 2021 Dec; 225():113779. PubMed ID: 34418785 [TBL] [Abstract][Full Text] [Related]
69. Design, synthesis and docking studies of Hydroxyethylamine and Hydroxyethylsulfide BACE-1 inhibitors. Rizzi L; Vaiana N; Sagui F; Genesio E; Pilli E; Porcari V; Romeo S Protein Pept Lett; 2009; 16(1):86-90. PubMed ID: 19149679 [TBL] [Abstract][Full Text] [Related]
70. Conformationally controlled mechanistic aspects of BACE 1 inhibitors. Sonker M; Yadav A Cent Nerv Syst Agents Med Chem; 2012 Mar; 12(1):28-37. PubMed ID: 22280413 [TBL] [Abstract][Full Text] [Related]
71. In vitro antiamyloidogenic properties of 1,4-naphthoquinones. Bermejo-Bescós P; Martín-Aragón S; Jiménez-Aliaga KL; Ortega A; Molina MT; Buxaderas E; Orellana G; Csákÿ AG Biochem Biophys Res Commun; 2010 Sep; 400(1):169-74. PubMed ID: 20709023 [TBL] [Abstract][Full Text] [Related]
72. Structure-based design of cycloamide-urethane-derived novel inhibitors of human brain memapsin 2 (beta-secretase). Ghosh AK; Devasamudram T; Hong L; DeZutter C; Xu X; Weerasena V; Koelsch G; Bilcer G; Tang J Bioorg Med Chem Lett; 2005 Jan; 15(1):15-20. PubMed ID: 15582402 [TBL] [Abstract][Full Text] [Related]
73. Screening and Elucidation of Selected Natural Compounds for Anti- Alzheimer's Potential Targeting BACE-1 Enzyme: A Case Computational Study. Ahmad SS; Akhtar S; Danish Rizvi SM; Kamal MA; Sayeed U; Khan MKA; Siddiqui MH; Arif JM Curr Comput Aided Drug Des; 2017 Nov; 13(4):311-318. PubMed ID: 28413992 [TBL] [Abstract][Full Text] [Related]
77. Optimisation of BACE1 inhibition of tripartite structures by modification of membrane anchors, spacers and pharmacophores - development of potential agents for the treatment of Alzheimer's disease. Linning P; Haussmann U; Beyer I; Weidlich S; Schieb H; Wiltfang J; Klafki HW; Knölker HJ Org Biomol Chem; 2012 Oct; 10(41):8216-35. PubMed ID: 22930158 [TBL] [Abstract][Full Text] [Related]
78. New isoquinolinequinone alkaloids from the South China Sea nudibranch Jorunna funebris and its possible sponge-prey Xestospongia sp. He WF; Li Y; Feng MT; Gavagnin M; Mollo E; Mao SC; Guo YW Fitoterapia; 2014 Jul; 96():109-14. PubMed ID: 24769286 [TBL] [Abstract][Full Text] [Related]