BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 20505744)

  • 1. The glutamate release inhibitor Riluzole decreases migration, invasion, and proliferation of melanoma cells.
    Le MN; Chan JL; Rosenberg SA; Nabatian AS; Merrigan KT; Cohen-Solal KA; Goydos JS
    J Invest Dermatol; 2010 Sep; 130(9):2240-9. PubMed ID: 20505744
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma.
    Namkoong J; Shin SS; Lee HJ; Marín YE; Wall BA; Goydos JS; Chen S
    Cancer Res; 2007 Mar; 67(5):2298-305. PubMed ID: 17332361
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Concurrent Targeting of Glutaminolysis and Metabotropic Glutamate Receptor 1 (GRM1) Reduces Glutamate Bioavailability in GRM1
    Shah R; Singh SJ; Eddy K; Filipp FV; Chen S
    Cancer Res; 2019 Apr; 79(8):1799-1809. PubMed ID: 30987979
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glutamatergic pathway targeting in melanoma: single-agent and combinatorial therapies.
    Lee HJ; Wall BA; Wangari-Talbot J; Shin SS; Rosenberg S; Chan JL; Namkoong J; Goydos JS; Chen S
    Clin Cancer Res; 2011 Nov; 17(22):7080-92. PubMed ID: 21844014
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disruption of GRM1-mediated signalling using riluzole results in DNA damage in melanoma cells.
    Wall BA; Wangari-Talbot J; Shin SS; Schiff D; Sierra J; Yu LJ; Khan A; Haffty B; Goydos JS; Chen S
    Pigment Cell Melanoma Res; 2014 Mar; 27(2):263-74. PubMed ID: 24330389
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Riluzole mediates anti-tumor properties in breast cancer cells independent of metabotropic glutamate receptor-1.
    Speyer CL; Nassar MA; Hachem AH; Bukhsh MA; Jafry WS; Khansa RM; Gorski DH
    Breast Cancer Res Treat; 2016 Jun; 157(2):217-228. PubMed ID: 27146584
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells.
    Martino JJ; Wall BA; Mastrantoni E; Wilimczyk BJ; La Cava SN; Degenhardt K; White E; Chen S
    Oncogene; 2013 Sep; 32(37):4366-76. PubMed ID: 23085756
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Blocking glutamate-mediated signalling inhibits human melanoma growth and migration.
    Song Z; He CD; Liu J; Sun C; Lu P; Li L; Gao L; Zhang Y; Xu Y; Shan L; Liu Y; Zou W; Zhang Y; Gao H; Gao W
    Exp Dermatol; 2012 Dec; 21(12):926-31. PubMed ID: 23171453
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A phase 0 trial of riluzole in patients with resectable stage III and IV melanoma.
    Yip D; Le MN; Chan JL; Lee JH; Mehnert JA; Yudd A; Kempf J; Shih WJ; Chen S; Goydos JS
    Clin Cancer Res; 2009 Jun; 15(11):3896-902. PubMed ID: 19458050
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of the glutamate receptor GRM1 enhances angiogenic signaling to drive melanoma progression.
    Wen Y; Li J; Koo J; Shin SS; Lin Y; Jeong BS; Mehnert JM; Chen S; Cohen-Sola KA; Goydos JS
    Cancer Res; 2014 May; 74(9):2499-509. PubMed ID: 24491800
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabotropic glutamate receptor-1: a potential therapeutic target for the treatment of breast cancer.
    Speyer CL; Smith JS; Banda M; DeVries JA; Mekani T; Gorski DH
    Breast Cancer Res Treat; 2012 Apr; 132(2):565-73. PubMed ID: 21681448
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Non-canonical Smads phosphorylation induced by the glutamate release inhibitor, riluzole, through GSK3 activation in melanoma.
    Abushahba W; Olabisi OO; Jeong BS; Boregowda RK; Wen Y; Liu F; Goydos JS; Lasfar A; Cohen-Solal KA
    PLoS One; 2012; 7(10):e47312. PubMed ID: 23077590
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Riluzole enhances ionizing radiation-induced cytotoxicity in human melanoma cells that ectopically express metabotropic glutamate receptor 1 in vitro and in vivo.
    Khan AJ; Wall B; Ahlawat S; Green C; Schiff D; Mehnert JM; Goydos JS; Chen S; Haffty BG
    Clin Cancer Res; 2011 Apr; 17(7):1807-14. PubMed ID: 21325066
    [TBL] [Abstract][Full Text] [Related]  

  • 14. AKT2 is a downstream target of metabotropic glutamate receptor 1 (Grm1).
    Shin SS; Wall BA; Goydos JS; Chen S
    Pigment Cell Melanoma Res; 2010 Feb; 23(1):103-11. PubMed ID: 19843246
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stimulation of oncogenic metabotropic glutamate receptor 1 in melanoma cells activates ERK1/2 via PKCepsilon.
    Marín YE; Namkoong J; Cohen-Solal K; Shin SS; Martino JJ; Oka M; Chen S
    Cell Signal; 2006 Aug; 18(8):1279-86. PubMed ID: 16305822
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional effects of GRM1 suppression in human melanoma cells.
    Wangari-Talbot J; Wall BA; Goydos JS; Chen S
    Mol Cancer Res; 2012 Nov; 10(11):1440-50. PubMed ID: 22798429
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A phase II trial of riluzole, an antagonist of metabotropic glutamate receptor 1 (GRM1) signaling, in patients with advanced melanoma.
    Mehnert JM; Silk AW; Lee JH; Dudek L; Jeong BS; Li J; Schenkel JM; Sadimin E; Kane M; Lin H; Shih WJ; Zloza A; Chen S; Goydos JS
    Pigment Cell Melanoma Res; 2018 Jul; 31(4):534-540. PubMed ID: 29453787
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Serum glutamate levels correlate with Gleason score and glutamate blockade decreases proliferation, migration, and invasion and induces apoptosis in prostate cancer cells.
    Koochekpour S; Majumdar S; Azabdaftari G; Attwood K; Scioneaux R; Subramani D; Manhardt C; Lorusso GD; Willard SS; Thompson H; Shourideh M; Rezaei K; Sartor O; Mohler JL; Vessella RL
    Clin Cancer Res; 2012 Nov; 18(21):5888-901. PubMed ID: 23072969
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Riluzole is a radio-sensitizing agent in an in vivo model of brain metastasis derived from GRM1 expressing human melanoma cells.
    Wall BA; Yu LJ; Khan A; Haffty B; Goydos JS; Chen S
    Pigment Cell Melanoma Res; 2015 Jan; 28(1):105-9. PubMed ID: 25363352
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The non-competitive metabotropic glutamate receptor-1 antagonist CPCCOEt inhibits the in vitro growth of human melanoma.
    Haas HS; Pfragner R; Siegl V; Ingolic E; Heintz E; Schraml E; Schauenstein K
    Oncol Rep; 2007 Jun; 17(6):1399-404. PubMed ID: 17487397
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.