BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 2050688)

  • 1. Structure-function relationships of human aromatase cytochrome P-450 using molecular modeling and site-directed mutagenesis.
    Graham-Lorence S; Khalil MW; Lorence MC; Mendelson CR; Simpson ER
    J Biol Chem; 1991 Jun; 266(18):11939-46. PubMed ID: 2050688
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evaluation of the mechanism of aromatase cytochrome P450. A site-directed mutagenesis study.
    Kao YC; Korzekwa KR; Laughton CA; Chen S
    Eur J Biochem; 2001 Jan; 268(2):243-51. PubMed ID: 11168357
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A site-directed mutagenesis study of human placental aromatase.
    Zhou DJ; Korzekwa KR; Poulos T; Chen SA
    J Biol Chem; 1992 Jan; 267(2):762-8. PubMed ID: 1730667
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-function studies of human aromatase.
    Chen S; Zhou D; Swiderek KM; Kadohama N; Osawa Y; Hall PF
    J Steroid Biochem Mol Biol; 1993 Mar; 44(4-6):347-56. PubMed ID: 8476748
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Use of molecular probes to study regulation of aromatase cytochrome P-450.
    Mendelson CR; Means GD; Mahendroo MS; Corbin CJ; Steinkampf MP; Graham-Lorence S; Simpson ER
    Biol Reprod; 1990 Jan; 42(1):1-10. PubMed ID: 1690030
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional ovarian and placental isoforms of porcine aromatase.
    Corbin CJ; Khalil MW; Conley AJ
    Mol Cell Endocrinol; 1995 Aug; 113(1):29-37. PubMed ID: 8674811
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of thromboxane A2 synthase active site residues by molecular modeling-guided site-directed mutagenesis.
    Wang LH; Matijevic-Aleksic N; Hsu PY; Ruan KH; Wu KK; Kulmacz RJ
    J Biol Chem; 1996 Aug; 271(33):19970-5. PubMed ID: 8702713
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutagenesis study at a postulated hydrophobic region near the active site of aromatase cytochrome P450.
    Zhou D; Cam LL; Laughton CA; Korzekwa KR; Chen S
    J Biol Chem; 1994 Jul; 269(30):19501-8. PubMed ID: 8034720
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional domains of human aromatase cytochrome P450 characterized by linear alignment and site-directed mutagenesis.
    Amarneh B; Corbin CJ; Peterson JA; Simpson ER; Graham-Lorence S
    Mol Endocrinol; 1993 Dec; 7(12):1617-24. PubMed ID: 8145767
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A detailed molecular model for human aromatase.
    Laughton CA; Zvelebil MJ; Neidle S
    J Steroid Biochem Mol Biol; 1993 Mar; 44(4-6):399-407. PubMed ID: 8476753
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Catalytic efficiency of expressed aromatase following site-directed mutagenesis.
    Kadohama N; Zhou D; Chen S; Osawa Y
    Biochim Biophys Acta; 1993 May; 1163(2):195-200. PubMed ID: 8490051
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Analysis of the catalytic activity of human factor XIIIa by site-directed mutagenesis.
    Hettasch JM; Greenberg CS
    J Biol Chem; 1994 Nov; 269(45):28309-13. PubMed ID: 7961769
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Study of substrate specificity of human aromatase by site directed mutagenesis.
    Auvray P; Nativelle C; Bureau R; Dallemagne P; Séralini GE; Sourdaine P
    Eur J Biochem; 2002 Mar; 269(5):1393-405. PubMed ID: 11874453
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The structure of cDNA clones encoding the aromatase P-450 isolated from a rat Leydig cell tumor line demonstrates differential processing of aromatase mRNA in rat ovary and a neoplastic cell line.
    Lephart ED; Peterson KG; Noble JF; George FW; McPhaul MJ
    Mol Cell Endocrinol; 1990 Mar; 70(1):31-40. PubMed ID: 2340950
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human placental estrogen synthetase (aromatase). Effect of environment on the kinetics of protein-protein and substrate-protein interactions and the production of 19-oxygenated androgen intermediates in the purified reconstituted cytochrome P450 enzyme system.
    Sethumadhavan K; Bellino FL
    J Steroid Biochem Mol Biol; 1991 Sep; 39(3):381-94. PubMed ID: 1911429
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-function studies of human aromatase by site-directed mutagenesis: kinetic properties of mutants Pro-308----Phe, Tyr-361----Phe, Tyr-361----Leu, and Phe-406----Arg.
    Zhou DJ; Pompon D; Chen SA
    Proc Natl Acad Sci U S A; 1991 Jan; 88(2):410-4. PubMed ID: 1988941
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ovarian aromatase cytochrome P-450 mRNA levels correlate with enzyme activity and serum estradiol levels in anestrous, pregnant and lactating rats.
    Lephart ED; Simpson ER; McPhaul MJ
    Mol Cell Endocrinol; 1992 Jun; 85(3):205-14. PubMed ID: 1634017
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inherent versatility of P-450 oxygenase. Conferring dehydroepiandrosterone hydroxylase activity to P-450 2a-4 by a single amino acid mutation at position 117.
    Iwasaki M; Darden TA; Parker CE; Tomer KB; Pedersen LG; Negishi M
    J Biol Chem; 1994 Mar; 269(12):9079-83. PubMed ID: 8132645
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The cytochrome P-450cam binding surface as defined by site-directed mutagenesis and electrostatic modeling.
    Stayton PS; Sligar SG
    Biochemistry; 1990 Aug; 29(32):7381-6. PubMed ID: 2223769
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of residues 363 and 206 in conversion of cytochrome P450 2B1 from a steroid 16-hydroxylase to a 15 alpha-hydroxylase.
    Luo Z; He YA; Halpert JR
    Arch Biochem Biophys; 1994 Feb; 309(1):52-7. PubMed ID: 8117113
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.