BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 20514024)

  • 1. EGR1 reactivation by histone deacetylase inhibitors promotes synovial sarcoma cell death through the PTEN tumor suppressor.
    Su L; Cheng H; Sampaio AV; Nielsen TO; Underhill TM
    Oncogene; 2010 Jul; 29(30):4352-61. PubMed ID: 20514024
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Histone deacetylase inhibitors reverse SS18-SSX-mediated polycomb silencing of the tumor suppressor early growth response 1 in synovial sarcoma.
    Lubieniecka JM; de Bruijn DR; Su L; van Dijk AH; Subramanian S; van de Rijn M; Poulin N; van Kessel AG; Nielsen TO
    Cancer Res; 2008 Jun; 68(11):4303-10. PubMed ID: 18519690
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Upregulation of ERK-EGR1-heparanase axis by HDAC inhibitors provides targets for rational therapeutic intervention in synovial sarcoma.
    Lanzi C; Favini E; Dal Bo L; Tortoreto M; Arrighetti N; Zaffaroni N; Cassinelli G
    J Exp Clin Cancer Res; 2021 Dec; 40(1):381. PubMed ID: 34857011
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma.
    Laporte AN; Barrott JJ; Yao RJ; Poulin NM; Brodin BA; Jones KB; Underhill TM; Nielsen TO
    PLoS One; 2017; 12(1):e0169407. PubMed ID: 28056055
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Death by HDAC Inhibition in Synovial Sarcoma Cells.
    Laporte AN; Poulin NM; Barrott JJ; Wang XQ; Lorzadeh A; Vander Werff R; Jones KB; Underhill TM; Nielsen TO
    Mol Cancer Ther; 2017 Dec; 16(12):2656-2667. PubMed ID: 28878027
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MicroRNA miR-183 functions as an oncogene by targeting the transcription factor EGR1 and promoting tumor cell migration.
    Sarver AL; Li L; Subramanian S
    Cancer Res; 2010 Dec; 70(23):9570-80. PubMed ID: 21118966
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of cytotoxic agents disrupting synovial sarcoma oncoprotein interactions by proximity ligation assay.
    Laporte AN; Ji JX; Ma L; Nielsen TO; Brodin BA
    Oncotarget; 2016 Jun; 7(23):34384-94. PubMed ID: 27120803
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SS18-SSX fusion protein-induced Wnt/β-catenin signaling is a therapeutic target in synovial sarcoma.
    Trautmann M; Sievers E; Aretz S; Kindler D; Michels S; Friedrichs N; Renner M; Kirfel J; Steiner S; Huss S; Koch A; Penzel R; Larsson O; Kawai A; Tanaka S; Sonobe H; Waha A; Schirmacher P; Mechtersheimer G; Wardelmann E; Büttner R; Hartmann W
    Oncogene; 2014 Oct; 33(42):5006-16. PubMed ID: 24166495
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Histone deacetylase inhibitor trichostatin a potentiates doxorubicin-induced apoptosis by up-regulating PTEN expression.
    Pan L; Lu J; Wang X; Han L; Zhang Y; Han S; Huang B
    Cancer; 2007 Apr; 109(8):1676-88. PubMed ID: 17330857
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential roles of SS18-SSX fusion gene and insulin-like growth factor-1 receptor in synovial sarcoma cell growth.
    Törnkvist M; Natalishvili N; Xie Y; Girnita A; D'Arcy P; Brodin B; Axelson M; Girnita L
    Biochem Biophys Res Commun; 2008 Apr; 368(3):793-800. PubMed ID: 18267106
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics.
    Su L; Sampaio AV; Jones KB; Pacheco M; Goytain A; Lin S; Poulin N; Yi L; Rossi FM; Kast J; Capecchi MR; Underhill TM; Nielsen TO
    Cancer Cell; 2012 Mar; 21(3):333-47. PubMed ID: 22439931
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Significant growth suppression of synovial sarcomas by the histone deacetylase inhibitor FK228 in vitro and in vivo.
    Ito T; Ouchida M; Morimoto Y; Yoshida A; Jitsumori Y; Ozaki T; Sonobe H; Inoue H; Shimizu K
    Cancer Lett; 2005 Jun; 224(2):311-9. PubMed ID: 15914281
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SRC signaling is crucial in the growth of synovial sarcoma cells.
    Michels S; Trautmann M; Sievers E; Kindler D; Huss S; Renner M; Friedrichs N; Kirfel J; Steiner S; Endl E; Wurst P; Heukamp L; Penzel R; Larsson O; Kawai A; Tanaka S; Sonobe H; Schirmacher P; Mechtersheimer G; Wardelmann E; Büttner R; Hartmann W
    Cancer Res; 2013 Apr; 73(8):2518-28. PubMed ID: 23580575
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Anlotinib inhibits synovial sarcoma by targeting GINS1: a novel downstream target oncogene in progression of synovial sarcoma.
    Tang L; Yu W; Wang Y; Li H; Shen Z
    Clin Transl Oncol; 2019 Dec; 21(12):1624-1633. PubMed ID: 30963468
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The synovial-sarcoma-associated SS18-SSX2 fusion protein induces epigenetic gene (de)regulation.
    de Bruijn DR; Allander SV; van Dijk AH; Willemse MP; Thijssen J; van Groningen JJ; Meltzer PS; van Kessel AG
    Cancer Res; 2006 Oct; 66(19):9474-82. PubMed ID: 17018603
    [TBL] [Abstract][Full Text] [Related]  

  • 16. AML1-ETO triggers epigenetic activation of early growth response gene l, inducing apoptosis in t(8;21) acute myeloid leukemia.
    Fu L; Huang W; Jing Y; Jiang M; Zhao Y; Shi J; Huang S; Xue X; Zhang Q; Tang J; Dou L; Wang L; Nervi C; Li Y; Yu L
    FEBS J; 2014 Feb; 281(4):1123-31. PubMed ID: 24314118
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Histone Deacetylase Inhibitors Activate Tristetraprolin Expression through Induction of Early Growth Response Protein 1 (EGR1) in Colorectal Cancer Cells.
    Sobolewski C; Sanduja S; Blanco FF; Hu L; Dixon DA
    Biomolecules; 2015 Aug; 5(3):2035-55. PubMed ID: 26343742
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Downregulation of SS18-SSX1 expression by small interfering RNA inhibits growth and induces apoptosis in human synovial sarcoma cell line HS-SY-II in vitro.
    Peng C; Guo W; Yang Y; Zhao H
    Eur J Cancer Prev; 2008 Oct; 17(5):392-8. PubMed ID: 18714179
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin prevents synovial sarcoma proliferation via apoptosis in in vitro models.
    Terry J; Lubieniecka JM; Kwan W; Liu S; Nielsen TO
    Clin Cancer Res; 2005 Aug; 11(15):5631-8. PubMed ID: 16061882
    [TBL] [Abstract][Full Text] [Related]  

  • 20. EGR1 regulates radiation-induced apoptosis in head and neck squamous cell carcinoma.
    Yoon TM; Kim SA; Lee DH; Lee JK; Park YL; Lee KH; Chung IJ; Joo YE; Lim SC
    Oncol Rep; 2015 Apr; 33(4):1717-22. PubMed ID: 25710185
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.