These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 20514469)

  • 1. MEK1 and MEK2 isoforms regulate distinct functions in pancreatic cancer cells.
    Zhou L; Tan X; Kamohara H; Wang W; Wang B; Liu J; Egami H; Baba H; Dai X
    Oncol Rep; 2010 Jul; 24(1):251-5. PubMed ID: 20514469
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors.
    Voisin L; Julien C; Duhamel S; Gopalbhai K; Claveau I; Saba-El-Leil MK; Rodrigue-Gervais IG; Gaboury L; Lamarre D; Basik M; Meloche S
    BMC Cancer; 2008 Nov; 8():337. PubMed ID: 19014680
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential regulation of mitogen-activated protein/ERK kinase (MEK)1 and MEK2 and activation by a Ras-independent mechanism.
    Xu S; Khoo S; Dang A; Witt S; Do V; Zhen E; Schaefer EM; Cobb MH
    Mol Endocrinol; 1997 Oct; 11(11):1618-25. PubMed ID: 9328344
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ERK1/2 can feedback-regulate cellular MEK1/2 levels.
    Hong SK; Wu PK; Karkhanis M; Park JI
    Cell Signal; 2015 Oct; 27(10):1939-48. PubMed ID: 26163823
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments.
    Skarpen E; Flinder LI; Rosseland CM; Orstavik S; Wierød L; Oksvold MP; Skålhegg BS; Huitfeldt HS
    FASEB J; 2008 Feb; 22(2):466-76. PubMed ID: 17928366
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Homoharringtonine could induce quick protein synthesis of PSMD11 through activating MEK1/ERK1/2 signaling pathway in pancreatic cancer cells.
    Wang L; Zhao L; Wei G; Saur D; Seidler B; Wang J; Wang C; Qi T
    J Cell Biochem; 2018 Aug; 119(8):6644-6656. PubMed ID: 29665121
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Distinct effects of knocking down MEK1 and MEK2 on replication of herpes simplex virus type 2.
    Zhang H; Feng H; Luo L; Zhou Q; Luo Z; Peng Y
    Virus Res; 2010 Jun; 150(1-2):22-7. PubMed ID: 20172001
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RNAi-mediated MEK1 knock-down prevents ERK1/2 activation and abolishes human hepatocarcinoma growth in vitro and in vivo.
    Gailhouste L; Ezan F; Bessard A; Frémin C; Rageul J; Langouët S; Baffet G
    Int J Cancer; 2010 Mar; 126(6):1367-77. PubMed ID: 19816936
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road.
    Caunt CJ; Sale MJ; Smith PD; Cook SJ
    Nat Rev Cancer; 2015 Oct; 15(10):577-92. PubMed ID: 26399658
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MEK1 and MEK2 differentially regulate human insulin- and insulin glargine-induced human bladder cancer T24 cell proliferation.
    Liu SY; Liang Y; Lin TX; Su F; Liang WW; Uwe H; Li Y
    Chin Med J (Engl); 2012 Dec; 125(23):4197-201. PubMed ID: 23217386
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MiR-126 acts as a tumor suppressor in pancreatic cancer cells via the regulation of ADAM9.
    Hamada S; Satoh K; Fujibuchi W; Hirota M; Kanno A; Unno J; Masamune A; Kikuta K; Kume K; Shimosegawa T
    Mol Cancer Res; 2012 Jan; 10(1):3-10. PubMed ID: 22064652
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Involvement of the mitogen-activated protein kinase kinase 2 in the induction of cell dissociation in pancreatic cancer.
    Tan X; Egami H; Kamohara H; Ishikawa S; Kurizaki T; Yoshida N; Tamori Y; Takai E; Hirota M; Ogawa M
    Int J Oncol; 2004 Jan; 24(1):65-73. PubMed ID: 14654942
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dissection of Kinase Isoforms through Orthogonal and Chemical Inducible Signaling Cascades.
    Zheng S; Fan X; Wang J; Zhao J; Chen PR
    Chembiochem; 2017 Aug; 18(16):1593-1598. PubMed ID: 28561913
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MEK2 is sufficient but not necessary for proliferation and anchorage-independent growth of SK-MEL-28 melanoma cells.
    Lee CS; Dykema KJ; Hawkins DM; Cherba DM; Webb CP; Furge KA; Duesbery NS
    PLoS One; 2011 Feb; 6(2):e17165. PubMed ID: 21365009
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RASSF7 promotes cell proliferation through activating MEK1/2-ERK1/2 signaling pathway in hepatocellular carcinoma.
    Zhang M; Li Q; Zhang L; Wang Y; Wang L; Li Q; He T; Wan B; Wang X
    Cell Mol Biol (Noisy-le-grand); 2018 Apr; 64(5):73-79. PubMed ID: 29729697
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Leydig cell MEK/ERK pathway is critical for maintaining a functional population of adult Leydig cells and for fertility.
    Yamashita S; Tai P; Charron J; Ko C; Ascoli M
    Mol Endocrinol; 2011 Jul; 25(7):1211-22. PubMed ID: 21527500
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of invasion-metastasis mechanism in pancreatic cancer: involvement of tight junction transmembrane protein occludin and MEK/ERK signal transduction pathway in cancer cell dissociation.
    Tan X; Tamori Y; Egami H; Ishikawa S; Kurizaki T; Takai E; Hirota M; Ogawa M
    Oncol Rep; 2004 May; 11(5):993-8. PubMed ID: 15069537
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of mRNA profiles after MEK1/2 inhibition in human pancreatic cancer cell lines reveals pathways involved in drug sensitivity.
    Gysin S; Paquette J; McMahon M
    Mol Cancer Res; 2012 Dec; 10(12):1607-19. PubMed ID: 22833572
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Relationship between activation of epidermal growth factor receptor and cell dissociation in pancreatic cancer.
    Tan X; Egami H; Ishikawa S; Nakagawa M; Ishiko T; Kamohara H; Hirota M; Ogawa M
    Int J Oncol; 2004 Nov; 25(5):1303-9. PubMed ID: 15492819
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Arrangement of expression and distribution of tight junction protein claudin-1 in cell dissociation of pancreatic cancer cells.
    Tan X; Egami H; Ishikawa S; Kurizaki T; Nakagawa M; Hirota M; Ogawa M
    Int J Oncol; 2004 Dec; 25(6):1567-74. PubMed ID: 15547692
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.