BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 20514469)

  • 1. MEK1 and MEK2 isoforms regulate distinct functions in pancreatic cancer cells.
    Zhou L; Tan X; Kamohara H; Wang W; Wang B; Liu J; Egami H; Baba H; Dai X
    Oncol Rep; 2010 Jul; 24(1):251-5. PubMed ID: 20514469
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors.
    Voisin L; Julien C; Duhamel S; Gopalbhai K; Claveau I; Saba-El-Leil MK; Rodrigue-Gervais IG; Gaboury L; Lamarre D; Basik M; Meloche S
    BMC Cancer; 2008 Nov; 8():337. PubMed ID: 19014680
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential regulation of mitogen-activated protein/ERK kinase (MEK)1 and MEK2 and activation by a Ras-independent mechanism.
    Xu S; Khoo S; Dang A; Witt S; Do V; Zhen E; Schaefer EM; Cobb MH
    Mol Endocrinol; 1997 Oct; 11(11):1618-25. PubMed ID: 9328344
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ERK1/2 can feedback-regulate cellular MEK1/2 levels.
    Hong SK; Wu PK; Karkhanis M; Park JI
    Cell Signal; 2015 Oct; 27(10):1939-48. PubMed ID: 26163823
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments.
    Skarpen E; Flinder LI; Rosseland CM; Orstavik S; Wierød L; Oksvold MP; Skålhegg BS; Huitfeldt HS
    FASEB J; 2008 Feb; 22(2):466-76. PubMed ID: 17928366
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Homoharringtonine could induce quick protein synthesis of PSMD11 through activating MEK1/ERK1/2 signaling pathway in pancreatic cancer cells.
    Wang L; Zhao L; Wei G; Saur D; Seidler B; Wang J; Wang C; Qi T
    J Cell Biochem; 2018 Aug; 119(8):6644-6656. PubMed ID: 29665121
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Distinct effects of knocking down MEK1 and MEK2 on replication of herpes simplex virus type 2.
    Zhang H; Feng H; Luo L; Zhou Q; Luo Z; Peng Y
    Virus Res; 2010 Jun; 150(1-2):22-7. PubMed ID: 20172001
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RNAi-mediated MEK1 knock-down prevents ERK1/2 activation and abolishes human hepatocarcinoma growth in vitro and in vivo.
    Gailhouste L; Ezan F; Bessard A; Frémin C; Rageul J; Langouët S; Baffet G
    Int J Cancer; 2010 Mar; 126(6):1367-77. PubMed ID: 19816936
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road.
    Caunt CJ; Sale MJ; Smith PD; Cook SJ
    Nat Rev Cancer; 2015 Oct; 15(10):577-92. PubMed ID: 26399658
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MEK1 and MEK2 differentially regulate human insulin- and insulin glargine-induced human bladder cancer T24 cell proliferation.
    Liu SY; Liang Y; Lin TX; Su F; Liang WW; Uwe H; Li Y
    Chin Med J (Engl); 2012 Dec; 125(23):4197-201. PubMed ID: 23217386
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MiR-126 acts as a tumor suppressor in pancreatic cancer cells via the regulation of ADAM9.
    Hamada S; Satoh K; Fujibuchi W; Hirota M; Kanno A; Unno J; Masamune A; Kikuta K; Kume K; Shimosegawa T
    Mol Cancer Res; 2012 Jan; 10(1):3-10. PubMed ID: 22064652
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Involvement of the mitogen-activated protein kinase kinase 2 in the induction of cell dissociation in pancreatic cancer.
    Tan X; Egami H; Kamohara H; Ishikawa S; Kurizaki T; Yoshida N; Tamori Y; Takai E; Hirota M; Ogawa M
    Int J Oncol; 2004 Jan; 24(1):65-73. PubMed ID: 14654942
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dissection of Kinase Isoforms through Orthogonal and Chemical Inducible Signaling Cascades.
    Zheng S; Fan X; Wang J; Zhao J; Chen PR
    Chembiochem; 2017 Aug; 18(16):1593-1598. PubMed ID: 28561913
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MEK2 is sufficient but not necessary for proliferation and anchorage-independent growth of SK-MEL-28 melanoma cells.
    Lee CS; Dykema KJ; Hawkins DM; Cherba DM; Webb CP; Furge KA; Duesbery NS
    PLoS One; 2011 Feb; 6(2):e17165. PubMed ID: 21365009
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RASSF7 promotes cell proliferation through activating MEK1/2-ERK1/2 signaling pathway in hepatocellular carcinoma.
    Zhang M; Li Q; Zhang L; Wang Y; Wang L; Li Q; He T; Wan B; Wang X
    Cell Mol Biol (Noisy-le-grand); 2018 Apr; 64(5):73-79. PubMed ID: 29729697
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Leydig cell MEK/ERK pathway is critical for maintaining a functional population of adult Leydig cells and for fertility.
    Yamashita S; Tai P; Charron J; Ko C; Ascoli M
    Mol Endocrinol; 2011 Jul; 25(7):1211-22. PubMed ID: 21527500
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of invasion-metastasis mechanism in pancreatic cancer: involvement of tight junction transmembrane protein occludin and MEK/ERK signal transduction pathway in cancer cell dissociation.
    Tan X; Tamori Y; Egami H; Ishikawa S; Kurizaki T; Takai E; Hirota M; Ogawa M
    Oncol Rep; 2004 May; 11(5):993-8. PubMed ID: 15069537
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of mRNA profiles after MEK1/2 inhibition in human pancreatic cancer cell lines reveals pathways involved in drug sensitivity.
    Gysin S; Paquette J; McMahon M
    Mol Cancer Res; 2012 Dec; 10(12):1607-19. PubMed ID: 22833572
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Relationship between activation of epidermal growth factor receptor and cell dissociation in pancreatic cancer.
    Tan X; Egami H; Ishikawa S; Nakagawa M; Ishiko T; Kamohara H; Hirota M; Ogawa M
    Int J Oncol; 2004 Nov; 25(5):1303-9. PubMed ID: 15492819
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Arrangement of expression and distribution of tight junction protein claudin-1 in cell dissociation of pancreatic cancer cells.
    Tan X; Egami H; Ishikawa S; Kurizaki T; Nakagawa M; Hirota M; Ogawa M
    Int J Oncol; 2004 Dec; 25(6):1567-74. PubMed ID: 15547692
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.