BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 20515662)

  • 1. The p85beta regulatory subunit of PI3K serves as a substrate for PTEN protein phosphatase activity during insulin mediated signaling.
    He J; de la Monte S; Wands JR
    Biochem Biophys Res Commun; 2010 Jul; 397(3):513-9. PubMed ID: 20515662
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Direct positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase.
    Chagpar RB; Links PH; Pastor MC; Furber LA; Hawrysh AD; Chamberlain MD; Anderson DH
    Proc Natl Acad Sci U S A; 2010 Mar; 107(12):5471-6. PubMed ID: 20212113
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes.
    Ono H; Katagiri H; Funaki M; Anai M; Inukai K; Fukushima Y; Sakoda H; Ogihara T; Onishi Y; Fujishiro M; Kikuchi M; Oka Y; Asano T
    Mol Endocrinol; 2001 Aug; 15(8):1411-22. PubMed ID: 11463863
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of tumor suppressor PTEN in tumor necrosis factor alpha-induced inhibition of insulin signaling in murine skeletal muscle C2C12 cells.
    Lo YT; Tzeng TF; Liu IM
    Horm Metab Res; 2007 Mar; 39(3):173-8. PubMed ID: 17373630
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
    Ozes ON; Akca H; Mayo LD; Gustin JA; Maehama T; Dixon JE; Donner DB
    Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4640-5. PubMed ID: 11287630
    [TBL] [Abstract][Full Text] [Related]  

  • 6. p85 Associates with unphosphorylated PTEN and the PTEN-associated complex.
    Rabinovsky R; Pochanard P; McNear C; Brachmann SM; Duke-Cohan JS; Garraway LA; Sellers WR
    Mol Cell Biol; 2009 Oct; 29(19):5377-88. PubMed ID: 19635806
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PTEN influences insulin and lipid metabolism in bovine hepatocytes in vitro.
    Deng Q; Ma D; Sun G; Yuan X; Wang Z; Liu G
    J Dairy Res; 2019 Feb; 86(1):73-76. PubMed ID: 30819264
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades.
    Lu Y; Yu Q; Liu JH; Zhang J; Wang H; Koul D; McMurray JS; Fang X; Yung WK; Siminovitch KA; Mills GB
    J Biol Chem; 2003 Oct; 278(41):40057-66. PubMed ID: 12869565
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN+/- mice by the p85 regulatory subunits of phosphoinositide 3-kinase.
    Luo J; Sobkiw CL; Logsdon NM; Watt JM; Signoretti S; O'Connell F; Shin E; Shim Y; Pao L; Neel BG; Depinho RA; Loda M; Cantley LC
    Proc Natl Acad Sci U S A; 2005 Jul; 102(29):10238-43. PubMed ID: 16006513
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphoinositide 3-kinase pathway activation in phosphate and tensin homolog (PTEN)-deficient prostate cancer cells is independent of receptor tyrosine kinases and mediated by the p110beta and p110delta catalytic subunits.
    Jiang X; Chen S; Asara JM; Balk SP
    J Biol Chem; 2010 May; 285(20):14980-14989. PubMed ID: 20231295
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes.
    Tang X; Powelka AM; Soriano NA; Czech MP; Guilherme A
    J Biol Chem; 2005 Jun; 280(23):22523-9. PubMed ID: 15824124
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Requirement of phosphoinositide 3-kinase and Akt for interferon-beta-mediated induction of the beta-R1 (SCYB11) gene.
    Rani MR; Hibbert L; Sizemore N; Stark GR; Ransohoff RM
    J Biol Chem; 2002 Oct; 277(41):38456-61. PubMed ID: 12169689
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PTEN regulation, a novel function for the p85 subunit of phosphoinositide 3-kinase.
    Barber DF; Alvarado-Kristensson M; González-García A; Pulido R; Carrera AC
    Sci STKE; 2006 Nov; 2006(362):pe49. PubMed ID: 17119157
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PTEN inhibits the migration and invasion of HepG2 cells by coordinately decreasing MMP expression via the PI3K/Akt pathway.
    Tian T; Nan KJ; Guo H; Wang WJ; Ruan ZP; Wang SH; Liang X; Lu CX
    Oncol Rep; 2010 Jun; 23(6):1593-600. PubMed ID: 20428814
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner.
    Song P; Wu Y; Xu J; Xie Z; Dong Y; Zhang M; Zou MH
    Circulation; 2007 Oct; 116(14):1585-95. PubMed ID: 17875968
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation and modulation of PTEN activity.
    Naderali E; Khaki AA; Rad JS; Ali-Hemmati A; Rahmati M; Charoudeh HN
    Mol Biol Rep; 2018 Dec; 45(6):2869-2881. PubMed ID: 30145641
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acute ethanol exposure inhibits insulin signaling in the liver.
    He J; de la Monte S; Wands JR
    Hepatology; 2007 Dec; 46(6):1791-800. PubMed ID: 18027876
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PTEN promotes intervertebral disc degeneration by regulating nucleus pulposus cell behaviors.
    Xi Y; Ma J; Chen Y
    Cell Biol Int; 2020 Feb; 44(2):583-592. PubMed ID: 31663655
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PI3K/AKT Pathway and Its Mediators in Thyroid Carcinomas.
    Nozhat Z; Hedayati M
    Mol Diagn Ther; 2016 Feb; 20(1):13-26. PubMed ID: 26597586
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Decreased phosphatase PTEN amplifies PI3K signaling and enhances proinflammatory cytokine release in COPD.
    Yanagisawa S; Baker JR; Vuppusetty C; Fenwick P; Donnelly LE; Ito K; Barnes PJ
    Am J Physiol Lung Cell Mol Physiol; 2017 Aug; 313(2):L230-L239. PubMed ID: 28522564
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.