These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 20515810)

  • 1. Mechanisms of protein aggregation in the retinal pigment epithelial cells.
    Kaarniranta K; Hyttinen J; Ryhanen T; Viiri J; Paimela T; Toropainen E; Sorri I; Salminen A
    Front Biosci (Elite Ed); 2010 Jun; 2(4):1374-84. PubMed ID: 20515810
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 5'-Adenosine monophosphate-activated protein kinase--mammalian target of rapamycin axis as therapeutic target for age-related macular degeneration.
    Hyttinen JM; Petrovski G; Salminen A; Kaarniranta K
    Rejuvenation Res; 2011 Dec; 14(6):651-60. PubMed ID: 22007913
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Heat shock proteins as gatekeepers of proteolytic pathways-Implications for age-related macular degeneration (AMD).
    Kaarniranta K; Salminen A; Eskelinen EL; Kopitz J
    Ageing Res Rev; 2009 Apr; 8(2):128-39. PubMed ID: 19274853
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration.
    Kaarniranta K; Uusitalo H; Blasiak J; Felszeghy S; Kannan R; Kauppinen A; Salminen A; Sinha D; Ferrington D
    Prog Retin Eye Res; 2020 Nov; 79():100858. PubMed ID: 32298788
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and age-related macular degeneration.
    Wang AL; Lukas TJ; Yuan M; Du N; Tso MO; Neufeld AH
    PLoS One; 2009; 4(1):e4160. PubMed ID: 19129916
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells.
    Ryhänen T; Hyttinen JM; Kopitz J; Rilla K; Kuusisto E; Mannermaa E; Viiri J; Holmberg CI; Immonen I; Meri S; Parkkinen J; Eskelinen EL; Uusitalo H; Salminen A; Kaarniranta K
    J Cell Mol Med; 2009 Sep; 13(9B):3616-31. PubMed ID: 19017362
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Autophagy in drusen biogenesis secondary to age-related macular degeneration.
    Hyttinen JMT; Koskela A; Blasiak J; Kaarniranta K
    Acta Ophthalmol; 2024 Nov; 102(7):759-772. PubMed ID: 39087629
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.
    Felszeghy S; Viiri J; Paterno JJ; Hyttinen JMT; Koskela A; Chen M; Leinonen H; Tanila H; Kivinen N; Koistinen A; Toropainen E; Amadio M; Smedowski A; Reinisalo M; Winiarczyk M; Mackiewicz J; Mutikainen M; Ruotsalainen AK; Kettunen M; Jokivarsi K; Sinha D; Kinnunen K; Petrovski G; Blasiak J; Bjørkøy G; Koskelainen A; Skottman H; Urtti A; Salminen A; Kannan R; Ferrington DA; Xu H; Levonen AL; Tavi P; Kauppinen A; Kaarniranta K
    Redox Biol; 2019 Jan; 20():1-12. PubMed ID: 30253279
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Defects in retinal pigment epithelial cell proteolysis and the pathology associated with age-related macular degeneration.
    Ferrington DA; Sinha D; Kaarniranta K
    Prog Retin Eye Res; 2016 Mar; 51():69-89. PubMed ID: 26344735
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular mechanisms of retinal pigment epithelium damage and development of age-related macular degeneration.
    Kinnunen K; Petrovski G; Moe MC; Berta A; Kaarniranta K
    Acta Ophthalmol; 2012 Jun; 90(4):299-309. PubMed ID: 22112056
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD.
    Mitter SK; Song C; Qi X; Mao H; Rao H; Akin D; Lewin A; Grant M; Dunn W; Ding J; Bowes Rickman C; Boulton M
    Autophagy; 2014; 10(11):1989-2005. PubMed ID: 25484094
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mitophagy in the Retinal Pigment Epithelium of Dry Age-Related Macular Degeneration Investigated in the
    Sridevi Gurubaran I; Viiri J; Koskela A; Hyttinen JMT; Paterno JJ; Kis G; Antal M; Urtti A; Kauppinen A; Felszeghy S; Kaarniranta K
    Int J Mol Sci; 2020 Mar; 21(6):. PubMed ID: 32183173
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of the ATP-driven proton pump in RPE lysosomes by the major lipofuscin fluorophore A2-E may contribute to the pathogenesis of age-related macular degeneration.
    Bergmann M; Schütt F; Holz FG; Kopitz J
    FASEB J; 2004 Mar; 18(3):562-4. PubMed ID: 14715704
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells.
    Johansson I; Monsen VT; Pettersen K; Mildenberger J; Misund K; Kaarniranta K; Schønberg S; Bjørkøy G
    Autophagy; 2015; 11(9):1636-51. PubMed ID: 26237736
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cigarette smoke-related hydroquinone dysregulates MCP-1, VEGF and PEDF expression in retinal pigment epithelium in vitro and in vivo.
    Pons M; Marin-Castaño ME
    PLoS One; 2011 Feb; 6(2):e16722. PubMed ID: 21386905
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glucosamine-Induced Autophagy through AMPK⁻mTOR Pathway Attenuates Lipofuscin-Like Autofluorescence in Human Retinal Pigment Epithelial Cells In Vitro.
    Chen CL; Chen YH; Liang CM; Tai MC; Lu DW; Chen JT
    Int J Mol Sci; 2018 May; 19(5):. PubMed ID: 29747425
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cells.
    Viiri J; Amadio M; Marchesi N; Hyttinen JM; Kivinen N; Sironen R; Rilla K; Akhtar S; Provenzani A; D'Agostino VG; Govoni S; Pascale A; Agostini H; Petrovski G; Salminen A; Kaarniranta K
    PLoS One; 2013; 8(7):e69563. PubMed ID: 23922739
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cellular Uptake and Delivery of Myeloperoxidase to Lysosomes Promote Lipofuscin Degradation and Lysosomal Stress in Retinal Cells.
    Yogalingam G; Lee AR; Mackenzie DS; Maures TJ; Rafalko A; Prill H; Berguig GY; Hague C; Christianson T; Bell SM; LeBowitz JH
    J Biol Chem; 2017 Mar; 292(10):4255-4265. PubMed ID: 28115520
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells.
    Krohne TU; Stratmann NK; Kopitz J; Holz FG
    Exp Eye Res; 2010 Mar; 90(3):465-71. PubMed ID: 20059996
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium.
    Thampi P; Rao HV; Mitter SK; Cai J; Mao H; Li H; Seo S; Qi X; Lewin AS; Romano C; Boulton ME
    PLoS One; 2012; 7(4):e34468. PubMed ID: 22509307
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.